Peanut consumption increases levels of plasma very long chain fatty acids in humans
Abstract
Peanut consumption has been suspected of raising plasma very long chain fatty acid (VLCFA) levels in humans. The effect of peanut consumption on VLCFAs was studied in six human subjects. After 3 to 4h of peanut butter ingestion, plasma C26:0 and C26:0/C22:0 were found to be significantly elevated to levels seen in patients with peroxisomal disorders. These levels returned to normal within 12h. Peanut consumption needs to be accounted for when interpreting VLCFAs.
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Plasma VLCFA levels strongly depend on dietary intake of VLCFAs, for example by consumption of peanuts.
“One possible diagnostic pitfall is the fact that plasma VLCFA levels strongly depend on dietary intake of VLCFAs, for example, by the consumption of peanuts.40”
From The genetic landscape of X-linked adrenoleukodystrophy: inheritance, mutations, modifier genes, and diagnosis (2015) · cites this paper as [40]
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Berger, J., Wiesinger, C., & Eichler, F. (2015) · The Application of Clinical Genetics · doi:10.2147/tacg.s49590 · Cited by 140 · see citing works
Lemaitre, R. N., Fretts, A. M., Sitlani, C. M., Biggs, M. L., Mukamal, K., King, I. B., Song, X., Djoussé, L., Siscovick, D. S., McKnight, B., et al. (2015) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.114.101857 · Cited by 117 · see citing works
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- Authors
- Lam, C., Wong, D., Cederbaum, S., Lim, B., & Qu, Y.
- Affiliations
- University of California, Los Angeles (US)
- Kaiser Permanente (US)
- Corresponding author
- Lam, Christina
- Venue
- Molecular Genetics and Metabolism
- Publisher
- Elsevier BV
- Published
- 2012-11
- Volume
- 107
- Issue
- 3
- Pages
- 620-622
- ISSN
- 1096-7192 (ISSN-L)
- OpenAlex
- W2000766319
- Cited by
- 45
- References
- 2
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 6 · 2023: 1 · 2022: 7 · 2021: 5 · 2020: 3 · 2019: 2 · 2018: 3 · 2017: 3 · 2016: 5 · 2015: 3 · 2014: 1
- FWCI
- 0.82
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Molecular Genetics and Metabolism (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Metabolism and Genetic Disorders
- Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
- Health Sciences › Nursing › Nutrition and Dietetics › Nuts composition and effects
- Keywords
- peanut consumption, peanut butter, very long chain fatty acids, plasma fatty acids, peroxisomal disorders, dietary fatty acid intake
- MeSH terms
- Adult, Aged, Fatty Acids, Female, Food, Humans, Middle Aged, Molecular Weight, Arachis, Prospective Studies, Peroxisomal Disorders, Postprandial Period
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