Usefulness of plasma glucose and insulin concentrations in identifying patients with insulin resistance
Abstract
In this study, a specific measurement of insulin-mediated glucose disposal was used in 490 healthy volunteers to classify subjects as being insulin resistant. We then made standard measurements of plasma glucose and insulin concentrations to see how useful they would be as surrogate markers of insulin resistance.
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APOE genotyping was performed with allele-specific PCR with universal molecular beacons, and DNA sequencing of positive control DNA samples was completed to assure correct assignment of alleles.
“Genotyping of APOE polymorphisms rs7412 and rs429358 was performed at PreventionGenetics (www.preventiongenetics.com) with an array tape [58] using allele-specific PCR with universal molecular beacons [59, 60]. DNA sequencing of positive control DNA samples were completed to assure correct assignment of alleles.”
From Metformin in Amnestic Mild Cognitive Impairment: Results of a Pilot Randomized Placebo Controlled Clinical Trial (2016) · cites this paper as [58]
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INDICADORES DE SÍNDROME METABÓLICA EM MENINAS
Filho, M., & Araraquara, C. D. (2005)
- Authors
- Tuan, C.-Y., Abbasi, F., Lamendola, C., McLaughlin, T., & Reaven, G.
- Affiliations
- Stanford Medicine (US)
- Corresponding author
- Reaven, Gerald
- Venue
- The American Journal of Cardiology
- Publisher
- Elsevier BV
- Published
- 2003-09
- Volume
- 92
- Issue
- 5
- Pages
- 606-610
- ISSN
- 0002-9149 (ISSN-L)
- OpenAlex
- W1973528637
- Cited by
- 34
- References
- 21
- Citations by year
- 2022: 1 · 2020: 2 · 2016: 2 · 2015: 1 · 2014: 1 · 2012: 1
- FWCI
- 2.65
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The American Journal of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diet, Metabolism, and Disease
- Health Sciences › Medicine › Epidemiology › Adipokines, Inflammation, and Metabolic Diseases
- Keywords
- insulin resistance, plasma glucose, insulin levels, insulin-stimulated glucose disposal, surrogate markers, healthy volunteers, insulin sensitivity
- MeSH terms
- Aged, Blood Glucose, Cardiovascular Diseases, Fasting, Female, Glucose, Glucose Tolerance Test, Humans, Infusions, Intravenous, Insulin, Insulin Resistance, Male, Middle Aged, Predictive Value of Tests, Reference Values, Risk Factors, Somatostatin, Biomarkers, Metabolic Syndrome
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