The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Depot leuprolide versus danazol in treatment of women with symptomatic endometriosis
Abstract
Objective We aimed to assess the efficacy of depot leuprolide versus danazol in the treatment of endometriosis. Study design A double-blind randomized trial of 270 patients from 22 centers compared the pretreatment and posttreatment laparoscopic extent of endometriosis. Pretreatment and posttreatment endometriosis symptoms and signs were assessed with standardized methods. Results When compared with danazol, leuprolide depot caused a more rapid and profound suppression of estradiol. Leuprolide depot and danazol were similarly efficacious in decreasing the extent of endometriosis, as well as the pain and tenderness associated with endometriosis. Conclusion Depot leuprolide is an effective alternative to danazol in decreasing the extent of endometriosis and endometriosis-related pain.
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“Third, change in endometriosis score has been used to assess treatment effect with the assumption, but no evidence, that lesion score correlates with pain score”
From Chronic pelvic pain and endometriosis: translational evidence of the relationship and implications (2011) · cites this paper as Wheeler et al., 1992
Citations
Cites
Revised American Fertility Society Classification of Endometriosis: 1985
(1985) · Fertility and Sterility · doi:10.1016/s0015-0282(16)48430-x · Cited by 1,803
Administration of Nasal Nafarelin as Compared with Oral Danazol for Endometriosis
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Goldfarb, A. F. (1970) · Fertility and Sterility · doi:10.1016/s0015-0282(16)37275-2 · Cited by 279
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Wheeler, J. M. (1989) · PubMed · Cited by 270
Self-citationDosage aspects of danazol therapy in endometriosis: Short-term and long-term effectiveness
Biberoglu, K. O., & Behrman, S. J. (1981) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(81)90478-6 · Cited by 267
Recurrent endometriosis: Incidence, management, and prognosis
Wheeler, J. M., & Malinak, L. R. (1983) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(83)90744-5 · Cited by 130
Self-citationCurrent Concepts of Endometriosis
Fox, H., & BUCKLEY, C. H. (1984) · Clinics in Obstetrics and Gynaecology · doi:10.1016/s0306-3356(21)00610-5 · Cited by 110
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Molgaard, C. A., Al, G., & Gresham, L. (1985) · PubMed Central · Cited by 67
Zorn, J.-R., Mathieson, J., Rísquez, F., Comaru‐Schally, A. M., & Schally, A. V. (1990) · Fertility and Sterility · doi:10.1016/s0015-0282(16)53330-5 · Cited by 36
Leuprolide acetate for the treatment of endometriosis.
Miller, J. (1990) · PubMed · Cited by 19
Self-citation
Research works printed but not linked: 1
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Cited by
Sorted by citations
Chronic pelvic pain and endometriosis: translational evidence of the relationship and implications
Stratton, P., & Berkley, K. J. (2011) · Human Reproduction Update · doi:10.1093/humupd/dmq050 · Cited by 442
One- and three-month release injectable microspheres of the LH-RH superagonist leuprorelin acetate
Okada, H. (1997) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(97)00050-1 · Cited by 380
Systematic review of endometriosis pain assessment: how to choose a scale?
Bourdel, N., Alves, J., Pickering, G. P., Ramilo, I. D. T. M., Roman, H., & Canis, M. J. (2014) · Human Reproduction Update · doi:10.1093/humupd/dmu046 · Cited by 378
Olive, D. L., & Pritts, E. A. (2001) · New England Journal of Medicine · doi:10.1056/nejm200107263450407 · Cited by 340
Reevaluating response and failure of medical treatment of endometriosis: a systematic review
Becker, C. M., Gattrell, W. T., Gude, K., & Singh, S. S. (2017) · Fertility and Sterility · doi:10.1016/j.fertnstert.2017.05.004 · Cited by 302
Metadata
- Authors
- Wheeler, J. M., Knittle, J. D., & Miller, J. D.
- Affiliations
- Houston Methodist (US)
- Deerfield (United States) (US)
- Corresponding author
- Miller, James D.
- Venue
- American Journal of Obstetrics and Gynecology
- Publisher
- Elsevier BV
- Published
- 1992-11
- Volume
- 167
- Issue
- 5
- Pages
- 1367-1371
- ISSN
- 0002-9378 (ISSN-L)
- OpenAlex
- W16600810
- Cited by
- 106
- References
- 11
- Citations by year
- 2026: 1 · 2024: 2 · 2023: 1 · 2022: 1 · 2020: 2 · 2019: 1 · 2018: 2 · 2017: 2 · 2016: 2 · 2015: 2 · 2014: 4 · 2013: 3 · 2012: 1
- FWCI
- 3.47
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Obstetrics and Gynecology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Health Sciences › Medicine › Obstetrics and Gynecology › Ectopic Pregnancy Diagnosis and Management
- Health Sciences › Medicine › Obstetrics and Gynecology › Gynecological conditions and treatments
- Keywords
- endometriosis, danazol, estradiol suppression, endometriosis-associated pain, GnRH agonist therapy, treatment efficacy comparison
- MeSH terms
- Adolescent, Adult, Danazol, Delayed-Action Preparations, Double-Blind Method, Endometriosis, Estradiol, Female, Genital Neoplasms, Female, Humans, Laparoscopy, Leuprolide
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