The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.
Effect of hemofiltrated whole blood pump priming on hemodynamics and respiratory function after the arterial switch operation in neonates
Abstract
Background Primed blood might have some deleterious effects on neonates during cardiopulmonary bypass (CPB) due to unbalanced electrolytes and inflammatory mediators. We hemofiltrated pump-primed blood before CPB to reduce inflammatory mediators and to adjust pH and the concentrations of electrolytes. The current study investigated the effects of hemofiltrated whole blood priming on hemodynamics and respiratory function after CPB in neonates. Methods Patients who underwent the arterial switch operation in the neonatal period for transposition of the great arteries with intact ventricular septum were chosen for this study. Seventeen patients underwent CPB with hemofiltrated blood priming (group HF) and 23 patients underwent CPB with nonhemofiltrated blood priming (group N). The concentrations of electrolytes and bradykinin and high molecular weight kininogen of the primed blood before and after hemofiltration were measured. At 4 hours after completion of CPB, the left ventricular percent fractional shortening, and the relation between the mean velocity of shortening and the end-systolic wall stress (stress velocity index), were measured by echocardiogram in 7 patients in group HF and 6 patients in group N. Alveolar--arterial oxygen tension difference (AaDO2) and respiratory index (AaDO2 divided by arterial oxygen tension) were measured at several points for 48 hours after CPB in all patients. Results Hemofiltration of the primed blood maintained electrolytes within a physiolog…
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“The exposure of the patient’s blood elements to the foreign surface of the bypass circuit induces a systemic inflammatory response, leading to capillary leak, edema formation, and myocardial diastolic and systolic dysfunction [3-6].”
From Management of the Low Cardiac Output Syndrome Following Surgery for Congenital Heart Disease (2016) · cites this paper as [4]
In the citing paper
“The systemic and regional inflammatory response that occurs with cardiopulmonary bypass and reperfusion injury increases total body oxygen demand while impairing oxygenation, cardiac output and systemic oxygen delivery [3-6].”
From Management of the Low Cardiac Output Syndrome Following Surgery for Congenital Heart Disease (2016) · cites this paper as [4]
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Complement activation and neutropenia occurring during cardiopulmonary bypass
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Cytokine production and hemofiltration in children undergoing cardiopulmonary bypass
Millar, A., Armstrong, L., van der Linden, J., Moat, N. E., Ekroth, R., Westwick, J. K., Scallan, M. H., & Lincoln, C. R. (1993) · The Annals of Thoracic Surgery · doi:10.1016/0003-4975(93)90740-9 · Cited by 169
Blood activation during neonatal extracorporeal life support
Plötz, F. B., van Oeveren, W., Bartlett, R. H., & Wildevuur, C. R. H. (1993) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/s0022-5223(19)34156-x · Cited by 165
Induction of interleukin-8 expression during cardiopulmonary bypass.
Kalfin, R. E., Engelman, R. M., Rousou, J. A., Flack, J. E., Deaton, D. W., Kreutzer, D. L., & Das, D. K. (1993) · PubMed · Cited by 130
Platelet and neutrophil activation in cardiopulmonary bypass
Colman, R. W. (1990) · The Annals of Thoracic Surgery · doi:10.1016/0003-4975(90)90352-7 · Cited by 112
Cited by
Hoffman, T. M., Wernovsky, G., Atz, A. M., Kulik, T. J., Nelson, D. P., Chang, A. C., Bailey, J. M., Akbary, A., Kocsis, J. F., Kaczmarek, R., et al. (2003) · Circulation · doi:10.1161/01.cir.0000051365.81920.28 · Cited by 772
Management of the Low Cardiac Output Syndrome Following Surgery for Congenital Heart Disease
K. Chandler, H., & Kirsch, R. (2016) · Current Cardiology Reviews · doi:10.2174/1573403x12666151119164647 · Cited by 74
Metadata
- Authors
- Nagashima, M., Imai, Y., Seo, K., Terada, M., Aoki, M., Shin’oka, T., & Koide, M.
- Affiliations
- Tokyo Women's Medical University (JP)
- Corresponding author
- Nagashima, Mitsugi
- Venue
- The Annals of Thoracic Surgery
- Publisher
- Elsevier BV
- Published
- 2000-12
- Volume
- 70
- Issue
- 6
- Pages
- 1901-1906
- ISSN
- 0003-4975 (ISSN-L)
- OpenAlex
- W2049966366
- Cited by
- 38
- References
- 26
- Citations by year
- 2026: 1 · 2024: 1 · 2023: 2 · 2021: 1 · 2020: 1 · 2019: 3 · 2018: 1 · 2017: 1 · 2016: 2 · 2015: 1 · 2013: 3 · 2012: 2
- FWCI
- 1.80
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- Locations
- The Annals of Thoracic Surgery (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Cardiac and Coronary Surgery Techniques
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Congenital Heart Disease Studies
- Health Sciences › Medicine › Hematology › Blood transfusion and management
- Keywords
- hemofiltration, pump priming, cardiopulmonary bypass, arterial switch operation, transposition of the great arteries, neonates, bradykinin, high molecular weight kininogen, hemodynamics, left ventricular function, respiratory function, alveolar-arterial oxygen difference, inflammatory mediators, electrolyte balance, postoperative outcomes, congenital heart surgery
- MeSH terms
- Cardiopulmonary Bypass, Electrolytes, Female, Hemodynamics, Hemofiltration, Humans, Infant, Newborn, Male, Oxygen, Postoperative Complications, Transposition of Great Vessels, Treatment Outcome
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