The DOI matches its Crossref record; 78 of the 78 references it cites were found in a registry or an index.
Some conservative strategies are effective when added to controlled mobilisation with external support after acute ankle sprain: a systematic review
Open accessAbstract
Questions Which intervention(s) best augment early mobilisation and external support after an acute ankle sprain? What is the most appropriate method of preventing re-injury?Design A systematic review of randomised controlled trials published from 1993 to April 2005.Participants People with an acute ankle sprain.Intervention Any pharmacological, physiotherapeutic, complementary or electrotherapeutic intervention added to controlled mobilisation with external support. Immobilisation, surgical intervention, and use of external ankle supports in isolation were excluded.Outcomes Pain, function, swelling, re-injury, and global improvement; assessed at short, intermediate, and long-term follow-up.Results 23 trials were included with a mean PEDro score of 6/10. There was strong evidence that non-steroidal anti-inflammatory drugs can reduce pain and improve short-term ankle function. There was moderate evidence that neuromuscular training decreases functional instability and minimises re-injury; and that comfrey root ointment decreases pain and improves function. There was also moderate evidence that manual therapy techniques improve ankle dorsiflexion. There was no evidence to support the use of electrophysical agents or hyperbaric oxygen therapy. Very few long-term follow-ups were undertaken, and few studies focused on preventing long-term morbidity.Conclusions Non-steroidal anti-inflammatory drugs, comfrey root ointment, and manual therapy can significantly improve short-term symptoms after ankle sprain, and neuromuscular training may prevent re-injury. More high quality studies are needed to develop evidence-based guidelines on ankle rehabilitation beyond the acute phases of injury management.
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“However, access to timely interventions remains a challenge, due to limitations in the availability of physical therapists, physical mobility, transportation and/or costs [24–27].”
From Telerehabilitation of acute musculoskeletal multi-disorders: prospective, single-arm, interventional study (2022) · cites this paper as [24]
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4 retracted
Immobilisation and functional treatment for acute lateral ankle ligament injuries in adults
Kerkhoffs, G. M. M. J., Rowe, B. H., Assendelft, W. J., Kelly, K. D., Struijs, P. A. A., & van Dijk, C. N. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd003762.pub2 · Cited by 167
RetractedImmobilisation and functional treatment for acute lateral ankle ligament injuries in adults
Kerkhoffs, G. M. M. J., Rowe, B. H., Assendelft, W. J., Kelly, K. D., Struijs, P. A. A., & van Dijk, C. N. (2002) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd003762 · Cited by 154
RetractedDifferent functional treatment strategies for acute lateral ankle ligament injuries in adults
Kerkhoffs, G. M. M. J., Struijs, P. A. A., Marti, R. K., Assendelft, W. J., Blankevoort, L., & van Dijk, C. N. (2002) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002938 · Cited by 125
RetractedDifferent functional treatment strategies for acute lateral ankle ligament injuries in adults
Kerkhoffs, G. M. M. J., Struijs, P. A. A., Marti, R. K., Assendelft, W. J., Blankevoort, L., & van Dijk, C. N. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002938.pub2 · Cited by 115
RetractedUpdated Method Guidelines for Systematic Reviews in the Cochrane Collaboration Back Review Group
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Functional Anatomy, Pathomechanics, and Pathophysiology of Lateral Ankle Instability.
Hertel, J. N. (2002) · PubMed · Cited by 1,405
An epidemiological survey on ankle sprain.
Yeung, M. S., Chan, K. M., So, C. H., & Yuan, W. Y. (1994) · British Journal of Sports Medicine · doi:10.1136/bjsm.28.2.112 · Cited by 687
Long term outcomes of inversion ankle injuries
Anandacoomarasamy, A., & Barnsley, L. (2005) · British Journal of Sports Medicine · doi:10.1136/bjsm.2004.011676 · Cited by 620
Flagged first, then by citations
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Gribble, P. A., Bleakley, C., Caulfield, B., Docherty, C. L., Fourchet, F., Fong, D. T.-P., Hertel, J. N., Hiller, C. E., Kaminski, T. W., McKeon, P. O., et al. (2016) · British Journal of Sports Medicine · doi:10.1136/bjsports-2016-096189 · Cited by 693
Self-citationDiagnosis, treatment and prevention of ankle sprains: update of an evidence-based clinical guideline
Vuurberg, G., Hoorntje, A., Wink, L. M., van der Doelen, B. F. W., van den Bekerom, M. P. J., Dekker, R., van Dijk, C. N., Krips, R., Loogman, M., Ridderikhof, M. L., et al. (2018) · British Journal of Sports Medicine · doi:10.1136/bjsports-2017-098106 · Cited by 557
Doherty, C., Bleakley, C., Delahunt, E., & Holden, S. (2016) · British Journal of Sports Medicine · doi:10.1136/bjsports-2016-096178 · Cited by 407
Self-citationKaminski, T. W., Hertel, J. N., Amendola, N., Docherty, C. L., Dolan, M. G., Hopkins, J. T., Nussbaum, E. D., Poppy, W., & Richie, D. (2013) · Journal of Athletic Training · doi:10.4085/1062-6050-48.4.02 · Cited by 276
Diagnosis, treatment and prevention of ankle sprains: an evidence-based clinical guideline
Kerkhoffs, G. M. M. J., van den Bekerom, M. P. J., Elders, L. A. M., van Beek, P. A., Hullegie, W., Bloemers, G. M. F. M., de Heus, E. M., Loogman, M., Rosenbrand, K., Kuipers, T., et al. (2012) · British Journal of Sports Medicine · doi:10.1136/bjsports-2011-090490 · Cited by 253
Metadata
- Authors
- Bleakley, C. M., McDonough, S. M., & MacAuley, D. C.
- Affiliations
- University of Ulster (GB)
- Corresponding author
- Bleakley, Chris M.
- Venue
- Australian Journal of Physiotherapy
- Publisher
- Elsevier BV
- Published
- 2008
- Volume
- 54
- Issue
- 1
- Pages
- 7-20
- ISSN
- 0004-9514 (ISSN-L)
- OpenAlex
- W2098339589
- Cited by
- 102
- References
- 78
- Citations by year
- 2025: 2 · 2024: 3 · 2023: 7 · 2022: 5 · 2021: 2 · 2020: 5 · 2019: 4 · 2018: 3 · 2017: 6 · 2016: 4 · 2015: 3 · 2014: 10 · 2013: 8 · 2012: 8
- FWCI
- 1.71
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Australian Journal of Physiotherapy (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Foot and Ankle Surgery
- Physical Sciences › Engineering › Biomedical Engineering › Lower Extremity Biomechanics and Pathologies
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Tendon Structure and Treatment
- Keywords
- acute ankle sprain, conservative treatment, early mobilization, external support, nonsteroidal anti-inflammatory drugs, neuromuscular training, manual therapy, ankle rehabilitation, reinjury prevention, ankle instability, ankle dorsiflexion, pain and function
- MeSH terms
- Combined Modality Therapy, Humans, Sprains and Strains, Ankle Injuries, Physical Therapy Modalities
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