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Some conservative strategies are effective when added to controlled mobilisation with external support after acute ankle sprain: a systematic review
Open accessAbstract
Questions Which intervention(s) best augment early mobilisation and external support after an acute ankle sprain? What is the most appropriate method of preventing re-injury?Design A systematic review of randomised controlled trials published from 1993 to April 2005.Participants People with an acute ankle sprain.Intervention Any pharmacological, physiotherapeutic, complementary or electrotherapeutic intervention added to controlled mobilisation with external support. Immobilisation, surgical intervention, and use of external ankle supports in isolation were excluded.Outcomes Pain, function, swelling, re-injury, and global improvement; assessed at short, intermediate, and long-term follow-up.Results 23 trials were included with a mean PEDro score of 6/10. There was strong evidence that non-steroidal anti-inflammatory drugs can reduce pain and improve short-term ankle function. There was moderate evidence that neuromuscular training decreases functional instability and minimises re-injury; and that comfrey root ointment decreases pain and improves function. There was also moderate evidence that manual therapy techniques improve ankle dorsiflexion. There was no evidence to support the use of electrophysical agents or hyperbaric oxygen therapy. Very few long-term follow-ups were undertaken, and few studies focused on preventing long-term morbidity.Conclusions Non-steroidal anti-inflammatory drugs, comfrey root ointment, and manual therapy can significantly improve short-term symptoms after ankle sprain, and neuromuscular training may prevent re-injury. More high quality studies are needed to develop evidence-based guidelines on ankle rehabilitation beyond the acute phases of injury management.
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“However, access to timely interventions remains a challenge, due to limitations in the availability of physical therapists, physical mobility, transportation and/or costs [24–27].”
From Telerehabilitation of acute musculoskeletal multi-disorders: prospective, single-arm, interventional study (2022) · cites this paper as [24]
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March 2009 Letters to the Editor-in-Chief
(2009) · Journal of Orthopaedic and Sports Physical Therapy · doi:10.2519/jospt.2009.0201
Lateral Ankle Sprains: Injury Epidemiology and Nonoperative Treatment
Abdelatif, N. M. N. (2022) · Springer eBooks · doi:10.1007/978-3-031-08682-3_6
Polzer, H. W., & Baumbach, S. F. (2023) · Springer Reference Medizin · doi:10.1007/978-3-642-54673-0_266-1
Bleakley, C., & Netterström-Wedin, F. (2023) · Figshare · doi:10.6084/m9.figshare.23564918
Self-citationGreen, T., Willson, G., & Fallon, K. E. (2020) · Figshare · doi:10.6084/m9.figshare.12057567
Metadata
- Authors
- Bleakley, C. M., McDonough, S. M., & MacAuley, D. C.
- Affiliations
- University of Ulster (GB)
- Corresponding author
- Bleakley, Chris M.
- Venue
- Australian Journal of Physiotherapy
- Publisher
- Elsevier BV
- Published
- 2008
- Volume
- 54
- Issue
- 1
- Pages
- 7-20
- ISSN
- 0004-9514 (ISSN-L)
- OpenAlex
- W2098339589
- Cited by
- 102
- References
- 78
- Citations by year
- 2025: 2 · 2024: 3 · 2023: 7 · 2022: 5 · 2021: 2 · 2020: 5 · 2019: 4 · 2018: 3 · 2017: 6 · 2016: 4 · 2015: 3 · 2014: 10 · 2013: 8 · 2012: 8
- FWCI
- 1.71
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Australian Journal of Physiotherapy (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Foot and Ankle Surgery
- Physical Sciences › Engineering › Biomedical Engineering › Lower Extremity Biomechanics and Pathologies
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Tendon Structure and Treatment
- Keywords
- acute ankle sprain, conservative treatment, early mobilization, external support, nonsteroidal anti-inflammatory drugs, neuromuscular training, manual therapy, ankle rehabilitation, reinjury prevention, ankle instability, ankle dorsiflexion, pain and function
- MeSH terms
- Combined Modality Therapy, Humans, Sprains and Strains, Ankle Injuries, Physical Therapy Modalities
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