The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.
Mitochondrial involvement in Alzheimer’s disease
Open accessAbstract
The causes of most neurodegenerative diseases, including sporadic Alzheimer's disease (AD), remain enigmatic. There is, however, increasing evidence implicating mitochondrial dysfunction resulting from deafferentiation of disconnected neural circuits in the pathogenesis of energy deficit in AD. The patterns of reduced expression of both mitochondrial DNA (mtDNA) and nuclear DNA (nDNA) encoded genes is consistent with a physiological down-regulation of the mitochondrial respiratory chain in response to reduced neuronal activity. On the other hand, the role(s) of somatic cell or maternally inherited mtDNA mutations in the pathogenesis of mitochondrial dysfunction in AD are still controversial.
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Cited by
Oxidative Stress and Neurotoxicity
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Brain fuel metabolism, aging, and Alzheimer’s disease
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Parkinson’s disease as a result of aging
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SIRT3 deregulation is linked to mitochondrial dysfunction in Alzheimer's disease
Lee, J., Kim, Y., Liu, T., Hwang, Y. J., Hyeon, S. J., Im, H., Lee, K., Alvarez, V. E., McKee, A. C., Um, S., et al. (2018) · Aging Cell · doi:10.1111/acel.12679 · Cited by 213
Metadata
- Authors
- Bonilla, E., Tanji, K., Hirano, M., Vu, T. H., DiMauro, S., & Schon, E. A.
- Venue
- Biochimica et Biophysica Acta (BBA) - Bioenergetics
- Publisher
- Elsevier BV
- Published
- 1999-02
- Volume
- 1410
- Issue
- 2
- Pages
- 171-182
- ISSN
- 0005-2728 (ISSN-L)
- OpenAlex
- W2031738386
- Cited by
- 169
- References
- 21
- FWCI
- 5.44
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Bonilla, E., Tanji, K., Hirano, M., Vu, T. H., DiMauro, S., & Schon, E. A. (1999). Mitochondrial involvement in Alzheimer’s disease. Biochimica et Biophysica Acta (BBA) - Bioenergetics. https://doi.org/10.1016/s0005-2728(98)00165-0
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
