The DOI matches its Crossref record; 43 of the 46 references it cites were found in a registry or an index.
Child's stress hormone levels correlate with mother's socioeconomic status and depressive state
Abstract
Background Individuals with lower socioeconomic status report greater exposure to stressful life events and a greater impact of these events on their lives than individuals with higher socioeconomic status, and this relationship between socioeconomic status and health begins at the earliest stages of life. To extend on these results, we performed a psychoneuroendocrine study of 217 children and 139 mothers.Methods Salivary cortisol levels and cognitive function were assessed in children, and a semistructured phone interview measuring symptoms of stress and depression was conducted with their mothers.Results Children with low socioeconomic status present significantly higher salivary cortisol levels than children with high socioeconomic status, and this socioeconomic status effect emerges as early as age 6. We also report that a child's cortisol level is significantly correlated with his or her mother's extent of depressive symptomatology.Conclusions These results offer a neurobiological determinant to the well-known association between socioeconomic status and health that begins early in life.
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“A study of school children in Quebec varying in age from 6 to 10 years shows that children of low SES have significantly higher salivary cortisol levels than those with high SES, with the largest differences becoming apparent at about age 10 (39).”
From Cortisol response to stress in female youths exposed to childhood maltreatment: results of the youth mood project (2009) · cites this paper as [39]
In the citing paper
“Indeed, a large body of evidence documents SES gradients for nearly all major peripheral biological parameters, including those reflecting HPA axis regulation, 60,62,66,70,72,[81][82][83][84][85] SNS activity, 60,71,72,81,83,85 heart rate variability (an index of autonomic balance), 60,[86][87][88] resting blood pressure, 61,66,69,83,89- and reaction to challenge (see Ref. 93 for review), lipids/m”
From Socio‐economic differentials in peripheral biology: Cumulative allostatic load (2010) · cites this paper as [62]
Citations
Cites
Protective and Damaging Effects of Stress Mediators
McEwen, B. S. (1998) · New England Journal of Medicine · doi:10.1056/nejm199801153380307 · Cited by 6,733 · cited 5×
“Although short-term glucocorticoid responses to stress serves an adaptive function (McEwen 1998), chronic exposure to elevated glucocorticoid concentrations contributes to the onset of physical pathologies and is associated with depressive symptomatology (Anderson and Armstead 1995; Lupien et al…”
BackgroundInfluentialSelf-citationSocial Origins of Depression: A Study of Psychiatric Disorder in Women.
Schnitzer, P. K., Brown, G. W., & Harris, T. (1980) · Contemporary Sociology A Journal of Reviews · doi:10.2307/2065631 · Cited by 3,053
Socioeconomic status and health: The challenge of the gradient
Adler, N. E., Boyce, T., Chesney, M. A., Cohen, S., Folkman, S., Kahn, R. L., & Syme, S. L. (1994) · American Psychologist · doi:10.1037/0003-066x.49.1.15 · Cited by 2,383
Social Origins of Depression: A Study of Psychiatric Disorder in Women
McDaniel, E. G. (1980) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-198009000-00013 · Cited by 1,894
Cortisol levels during human aging predict hippocampal atrophy and memory deficits
Lupien, S. J., de Leon, M., de Santi, S., Convit, A., Tarshish, C., Nair, N. P. V., Thakur, M., McEwen, B. S., Hauger, R. L., & Meaney, M. J. (1998) · Nature Neuroscience · doi:10.1038/271 · Cited by 1,653
Self-citationThe Use of Psychological Testing for Treatment Planning and Outcome Assessment
Maruish, M. E., & Leahy, R. L. (2000) · Journal of Cognitive Psychotherapy · doi:10.1891/0889-8391.14.2.205 · Cited by 1,634
Biological Bases of Childhood Shyness
Kagan, J., Reznick, J. S., & Snidman, N. (1988) · Science · doi:10.1126/science.3353713 · Cited by 1,577
The acute effects of corticosteroids on cognition: integration of animal and human model studies
LUPIEN, S., & MCEWEN, B. (1997) · Brain Research Reviews · doi:10.1016/s0165-0173(97)00004-0 · Cited by 1,024
Self-citationDisrupted 24-hour patterns of cortisol secretion in psychotic depression
Sachar, E. J. (1973) · Archives of General Psychiatry · doi:10.1001/archpsyc.1973.01750310011002 · Cited by 775
Weissman, M. M. (1987) · Archives of General Psychiatry · doi:10.1001/archpsyc.1987.01800220009002 · Cited by 574
Research works printed but not linked: 2
- Hammen, 1987, Maternal affective disorders, illness, and stress, Am J Psychiatry, 114, 736
- Lupien, 1997, Stress-induced declarative memory impairments in healthy elderly subjects, J Clin Endocrinol Metab, 82, 2070
Cited by
Sorted by citations
Effects of stress throughout the lifespan on the brain, behaviour and cognition
Lupien, S. J., McEwen, B. S., Gunnar, M. R., & Heim, C. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2639 · Cited by 6,256
Self-citationShonkoff, J. P., Boyce, W. T., & McEwen, B. S. (2009) · JAMA · doi:10.1001/jama.2009.754 · Cited by 2,326
Self-citationBOYCE, W. T., & ELLIS, B. J. (2005) · Development and Psychopathology · doi:10.1017/s0954579405050145 · Cited by 2,078
The neurobiology of stress and development.
Gunnar, M., & Quevedo, K. (2007) · Annual Review of Psychology · doi:10.1146/annurev.psych.58.110405.085605 · Cited by 2,011
Haushofer, J., & Fehr, E. (2014) · Science · doi:10.1126/science.1232491 · Cited by 1,638
Metadata
- Authors
- Lupien, S. J., King, S., Meaney, M. J., & McEwen, B. S.
- Affiliations
- Douglas Mental Health University Institute (CA)
- Rockefeller University (US)
- Corresponding author
- Lupien, Sonia J
- Venue
- Biological Psychiatry
- Publisher
- Elsevier BV
- Published
- 2000-11
- Volume
- 48
- Issue
- 10
- Pages
- 976-980
- ISSN
- 0006-3223 (ISSN-L)
- OpenAlex
- W2047909845
- Cited by
- 532
- References
- 46
- Citations by year
- 2026: 5 · 2025: 5 · 2024: 10 · 2023: 8 · 2022: 18 · 2021: 22 · 2020: 16 · 2019: 17 · 2018: 20 · 2017: 26 · 2016: 27 · 2015: 32 · 2014: 33 · 2013: 24 · 2012: 41
- FWCI
- 3.53
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biological Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Keywords
- socioeconomic status, salivary cortisol, childhood stress, maternal depression, depressive symptoms, psychoneuroendocrinology, cognitive function, early childhood, stress hormones
- MeSH terms
- Age Factors, Canada, Child, Depressive Disorder, Female, Hormones, Humans, Hydrocortisone, Male, Saliva, Social Class, Stress, Psychological
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