The DOI matches its Crossref record; 48 of the 48 references it cites were found in a registry or an index.
Interpersonal and social rhythm therapy: managing the chaos of bipolar disorder
Abstract
Interpersonal and social rhythm therapy is an individual psychotherapy designed specifically for the treatment for bipolar disorder. Interpersonal and social rhythm therapy grew from a chronobiological model of bipolar disorder postulating that individuals with bipolar disorder have a genetic predisposition to circadian rhythm and sleep-wake cycle abnormalities that may be responsible, in part, for the symptomatic manifestations of the illness. In our model, life events (both negative and positive) may cause disruptions in patients' social rhythms that, in turn, perturb circadian rhythms and sleep-wake cycles and lead to the development of bipolar symptoms. Administered in concert with medications, interpersonal and social rhythm therapy combines the basic principles of interpersonal psychotherapy with behavioral techniques to help patients regularize their daily routines, diminish interpersonal problems, and adhere to medication regimens. It modulates both biological and psychosocial factors to mitigate patients' circadian and sleep-wake cycle vulnerabilities, improve overall functioning, and better manage the potential chaos of bipolar disorder symptomatology.
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In the citing paper
“Treatments to amplify, phase advance or delay circadian rhythms have been developed for potential use in psychiatric disorders in adults.”
From Rhythms of life: circadian disruption and brain disorders across the lifespan (2019) · cites this paper as [189]
In the citing paper
“circadian disruptions can precipitate mood and psychotic episodes in individuals who already have psychiatric disorders189–191”
From Rhythms of life: circadian disruption and brain disorders across the lifespan (2019) · cites this paper as [189]
Citations
Cites
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Self-citationLithium salts in the treatment of psychotic excitement
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A Guide to Treatments that Work
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“In 1988, we proposed an etiologic model of major depression that focused on the role of disrupted social rhythms in the emergence of a depressive episode in biologically vulnerable individuals (Ehlers et al 1988).”
Reynolds III, C. F., Frank, E., Perel, J. M., Imber, S. D., Cornes, C., Miller, M. D., Mazumdar, S., Houck, P. R., Dew, M. A., Stack, J. A., et al. (1999) · JAMA · doi:10.1001/jama.281.1.39 · Cited by 659
Self-citationThe enduring psychosocial consequences of mania and depression
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Research works printed but not linked: 2
- Frank, 1999, Interpersonal and social rhythm therapy prevents depressive symptomatology in bipolar 1 patients, Bipolar Disord, 1, 13
- Wehr, 1987, Sleep reduction as a final common pathway in the genesis of mania, Am J Psychiatry, 144, 201
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Goodwin, G., Haddad, P. M., Ferrier, I. N., Aronson, J., Barnes, T., Cipriani, A., Coghill, D., Fazel, S., Geddes, J. R., Grunze, H., et al. (2016) · Journal of Psychopharmacology · doi:10.1177/0269881116636545 · Cited by 1,350
“The principles of IPSRT derive from interpersonal therapy, which has never itself been studied in bipolar patients (Frank et al., 2000).”
Treatment of Complicated Grief: A Randomized Controlled Trial
Shear, K., Frank, E., Houck, P. R., & Reynolds, C. F. (2005) · JAMA · doi:10.1001/jama.293.21.2601 · Cited by 1,097
“As suggested by results of a comparison of the 2 methods,(23) we have previously found that IPT and cognitive-behavioral therapy lend themselves to integration.(24,25) Following completion of an open trial of CGT,(21) we report here the results of a randomized controlled trial comparing CGT with standard IPT.”
ResultSelf-citationTiming to perfection: the biology of central and peripheral circadian clocks
Albrecht, U. (2012) · Neuron · doi:10.1016/j.neuron.2012.04.006 · Cited by 915
Sleep, insomnia, and depression
Riemann, D. W., Krone, L. B., Wulff, K., & Nissen, C. (2019) · Neuropsychopharmacology · doi:10.1038/s41386-019-0411-y · Cited by 901
Rhythms of life: circadian disruption and brain disorders across the lifespan
Logan, R. W., & McClung, C. A. (2019) · Nature Reviews Neuroscience · doi:10.1038/s41583-018-0088-y · Cited by 713
Metadata
- Authors
- Frank, E., Swartz, H. A., & Kupfer, D. J.
- Affiliations
- University of Pittsburgh (US)
- Corresponding author
- Frank, Ellen
- Venue
- Biological Psychiatry
- Publisher
- Elsevier BV
- Published
- 2000-09
- Volume
- 48
- Issue
- 6
- Pages
- 593-604
- ISSN
- 0006-3223 (ISSN-L)
- OpenAlex
- W2163455012
- Cited by
- 521
- References
- 47
- Citations by year
- 2026: 11 · 2025: 18 · 2024: 18 · 2023: 9 · 2022: 17 · 2021: 18 · 2020: 12 · 2019: 14 · 2018: 20 · 2017: 20 · 2016: 26 · 2015: 19 · 2014: 25 · 2013: 22 · 2012: 24
- FWCI
- 2.78
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biological Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Mental Health (MH60473, MH 29618, R25MH060473, MH30915)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Keywords
- interpersonal and social rhythm therapy, bipolar disorder, circadian rhythm, sleep-wake cycle, social rhythms, chronobiology, interpersonal psychotherapy, life events, medication adherence, psychosocial interventions
- MeSH terms
- Affect, Behavior Therapy, Bipolar Disorder, Combined Modality Therapy, Humans, Interpersonal Relations, Life Change Events, Models, Psychological, Psychotherapy, Tranquilizing Agents, Randomized Controlled Trials as Topic, Sleep Disorders, Circadian Rhythm
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