Cited by 488Stroke Rehabilitation and RecoveryTreatment of Major DepressionTranscranial Magnetic Stimulation Studies

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Post stroke depression: epidemiology, pathophysiology, and biological treatment

Whyte, Ellen M, Mulsant, Benoit H·2002·Biological Psychiatry

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Abstract

Depression is a common occurrence after stroke and is associated with excess disability, cognitive impairment, and mortality. The authors undertook a systematic review of the English language literature to review several aspects of this illness, including the prevalence of this disorder, the debate on its etiology, and the current understanding of the biological treatment of poststroke depression. Methodological problems encountered in the study of poststroke depression are highlighted throughout the manuscript. The authors conclude that the available evidence supports poststroke depression as being multifactorial in origin and consistent with the biopsychosocial model of mental illness.

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Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
The Need for a New Medical Model: A Challenge for Biomedicine
Engel, G. L. (1977) · Science · doi:10.1126/science.847460 · Cited by 12,887
J Neuropsychiatry Clin Neurosci
Yudofsky, S. C., & Hales, R. E. (1992) · The Journal of Neuropsychiatry and Clinical Neurosciences · doi:10.1176/jnp.4.4.359 · Cited by 3,818
Cognitive deficits in depression: Possible implications for functional neuropathology
Austin, M.-P., Mitchell, P., & Goodwin, G. M. (2001) · British Journal of Psychiatry · doi:10.1192/bjp.178.3.200 · Cited by 1,154
MOOD DISORDERS IN STROKE PATIENTS: IMPORTANCE OF LOCATION OF LESION
Robinson, R. G., Kubos, K. L., Starr, L. B., Rao, K. C. V. G., & Price, T. R. (1984) · Brain · doi:10.1093/brain/107.1.81 · Cited by 1,111
Life Events and Depression
Paykel, E. S. (1969) · Archives of General Psychiatry · doi:10.1001/archpsyc.1969.01740240113014 · Cited by 972
Major depression in stroke patients. A 3-year longitudinal study.
Aström, M., Adolfsson, R., & Asplund, K. (1993) · Stroke · doi:10.1161/01.str.24.7.976 · Cited by 689
Depression after stroke and lesion location: a systematic review
Carson, A. J., MacHale, S., Allen, K. E., Lawrie, S. M., Dennis, M. S., House, A. O., & Sharpe, M. (2000) · The Lancet · doi:10.1016/s0140-6736(00)02448-x · Cited by 650
Association Between Depression and Mortality in Older Adults
Schulz, R., Beach, S. R., Ives, D. G., Martire, L. M., Ariyo, A. A., & Kop, W. J. (2000) · Archives of Internal Medicine · doi:10.1001/archinte.160.12.1761 · Cited by 611
The Association of Late-Life Depression and Anxiety With Physical Disability: A Review of the Literature and Prospectus for Future Research
Lenze, E. J., Rogers, J. C., Martire, L. M., Mulsant, B. H., Rollman, B. L., Dew, M. A., Schulz, R., & Reynolds, C. F. (2001) · The American Journal of Geriatric Psychiatry · doi:10.1097/00019442-200105000-00004 · Cited by 593
Self-citation
Clinically defined vascular depression
(1997) · American Journal of Psychiatry · doi:10.1176/ajp.154.4.562 · Cited by 557
The prediction of major depression in women: toward an integrated etiologic model.
(1993) · American Journal of Psychiatry · doi:10.1176/ajp.150.8.1139 · Cited by 554
NORTRIPTYLINE TREATMENT OF POST-STROKE DEPRESSION: A DOUBLE-BLIND STUDY
Lipsey, J. R., Pearlson, G., Robinson, R. G., Rao, K. C. V. G., & Price, T. R. (1984) · The Lancet · doi:10.1016/s0140-6736(84)90356-8 · Cited by 536
The Impact of Poststroke Depression on Recovery in Activities of Daily Living Over a 2-Year Follow-up
Parikh, R. M., Robinson, R. G., Lipsey, J. R., STARKSTEIN, S. E., Fedoroff, J. P., & Price, T. R. (1990) · Archives of Neurology · doi:10.1001/archneur.1990.00530070083014 · Cited by 493
Association of depression with 10-year poststroke mortality
Morris, P. L. P., Robinson, R. G., Andrzejewski, P. L., SAMUELS, J. F., & Price, T. R. (1993) · American Journal of Psychiatry · doi:10.1176/ajp.150.1.124 · Cited by 473
The Sunnybrook Stroke Study
Herrmann, N., Black, S. E., Lawrence, J., Szekely, C. A., & Szalai, J. P. (1998) · Stroke · doi:10.1161/01.str.29.3.618 · Cited by 461
Mood change following left hemispheric brain injury
Robinson, R. G., & Szetela, B. R. (1981) · Annals of Neurology · doi:10.1002/ana.410090506 · Cited by 455
Mood disorder as a specific complication of stroke.
Folstein, M. F., Maiberger, R., & McHugh, P. R. (1977) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.40.10.1018 · Cited by 442
A two-year longitudinal study of post-stroke mood disorders: findings during the initial evaluation.
Robinson, R. G., Starr, L. B., Kubos, K. L., & Price, T. R. (1983) · Stroke · doi:10.1161/01.str.14.5.736 · Cited by 435
Poststroke Depression Correlates With Cognitive Impairment and Neurological Deficits
Kauhanen, M.-L., Korpelainen, J. T., Hiltunen, P., Brusin, E., Mononen, H., Määttä, R., Nieminen, P. A., Sotaniemi, K. A., & Myllylä, V. V. (1999) · Stroke · doi:10.1161/01.str.30.9.1875 · Cited by 434
Depression and Disability in Late Life: Directions for Future Research
BRUCE, M. L. (2001) · American Journal of Geriatric Psychiatry · doi:10.1097/00019442-200105000-00003 · Cited by 423
COMPARISON OF CORTICAL AND SUBCORTICAL LESIONS IN THE PRODUCTION OF POSTSTROKE MOOD DISORDERS
STARKSTEIN, S. E., Robinson, R. G., & Price, T. R. (1987) · Brain · doi:10.1093/brain/110.4.1045 · Cited by 422
Malingering in Accident and Disease
Collie, J. N. (1913) · The Lancet · Cited by 422
Social Origins of Depression in Old Age
Murphy, E. (1982) · The British Journal of Psychiatry · doi:10.1192/bjp.141.2.135 · Cited by 421
Mortality at 12 and 24 Months After Stroke May Be Associated With Depressive Symptoms at 1 Month
House, A. O., Knapp, P., Bamford, J., & Vail, A. (2001) · Stroke · doi:10.1161/01.str.32.3.696 · Cited by 401
Nortriptyline Versus Fluoxetine in the Treatment of Depression and in Short-Term Recovery After Stroke: A Placebo-Controlled, Double-Blind Study
Robinson, R. G., Schultz, S. K., CASTILLO, C. S., Kopel, T., Kosier, J. T., Newman, R., Curdue, K. J., Petracca, G., & STARKSTEIN, S. E. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.3.351 · Cited by 383
Effective treatment of poststroke depression with the selective serotonin reuptake inhibitor citalopram.
Andersen, G., Vestergaard, K., & Lauritzen, L. (1994) · Stroke · doi:10.1161/01.str.25.6.1099 · Cited by 378
Changes in Cognitive Functioning Following Treatment of Late-Life Depression
Butters, M. A., Becker, J. T., Nebes, R. D., Zmuda, M. D., Mulsant, B. H., Pollock, B. G., & Reynolds, C. F. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.12.1949 · Cited by 377
Self-citation
Depression After Stroke
Kotila, M., Numminen, H., Waltimo, O., & Kaste, M. (1998) · Stroke · doi:10.1161/01.str.29.2.368 · Cited by 375
Post-stroke depression: relationships to functional impairment, coping strategies, and rehabilitation outcome.
Sinyor, D., Amato, P., Kaloupek, D. G., Becker, R., Goldenberg, M., & Coopersmith, H. (1986) · Stroke · doi:10.1161/01.str.17.6.1102 · Cited by 373
Effects of Fluoxetine and Maprotiline on Functional Recovery in Poststroke Hemiplegic Patients Undergoing Rehabilitation Therapy
Dam, M., Tonin, P., Boni, A., Pizzolato, G., Casson, S., Ermani, M., Freo, U., Piron, L., & Battistin, L. (1996) · Stroke · doi:10.1161/01.str.27.7.1211 · Cited by 346
Life events and depression
Fava, G. A., Munari, F., Pavan, L. J., & Kellner, R. (1981) · Journal of Affective Disorders · doi:10.1016/0165-0327(81)90040-9 · Cited by 330
Generalized Anxiety Disorder in Stroke Patients: A 3-Year Longitudinal Study
Åström, M. (1996) · Stroke · doi:10.1161/01.str.27.2.270 · Cited by 329
Prefrontal cortex dysfunction in clinical depression
George, M. S., Ketter, T. A., & Post, R. M. (1994) · Depression · doi:10.1002/depr.3050020202 · Cited by 324
Prevalence of Depression After Stroke: The Perth Community Stroke Study
Burvill, P. W., Johnson, G. A., Jamrozik, K. D., Anderson, C. S., Stewart‐Wynne, E. G., & Chakera, T. M. H. (1995) · The British Journal of Psychiatry · doi:10.1192/bjp.166.3.320 · Cited by 307
Frontal White Matter Microstructure and Treatment Response of Late-Life Depression: A Preliminary Study
Alexopoulos, G. S., Kiosses, D. N., Choi, S. J., Murphy, C. F., & Lim, K. O. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.11.1929 · Cited by 307
Frequency and Clinical Determinants of Poststroke Depression
Pohjasvaara, T., Leppävuori, A., Siira, I., Vataja, R., Kaste, M., & Erkinjuntti, T. (1998) · Stroke · doi:10.1161/01.str.29.11.2311 · Cited by 301
Two-year longitudinal study of poststroke mood disorders: diagnosis and outcome at one and two years.
Robinson, R. G., BOLDUC, P. L., & Price, T. R. (1987) · Stroke · doi:10.1161/01.str.18.5.837 · Cited by 298
Antidepressant Therapy After Stroke
REDING, M. J. (1986) · Archives of Neurology · doi:10.1001/archneur.1986.00520080011011 · Cited by 297
Mood Disorders in the Year after First Stroke
House, A. O., Dennis, M. S., Mogridge, L., Warlow, C. P., Hawton, K. E., & Jones, L. (1991) · The British Journal of Psychiatry · doi:10.1192/bjp.158.1.83 · Cited by 290
Depressed Mood After Stroke
Wade, D. T., Legh-Smith, J., & Hewer, R. A. (1987) · The British Journal of Psychiatry · doi:10.1192/bjp.151.2.200 · Cited by 288
Depressive symptoms and history of depression predict rehabilitation efficiency in stroke patients
Gillen, R., Tennen, H., McKee, T. E., Gernert-Dott, P., & Affleck, G. (2001) · Archives of Physical Medicine and Rehabilitation · doi:10.1053/apmr.2001.26249 · Cited by 287
Poststroke depression and emotional incontinence
Kim, J. S., & Choi‐Kwon, S. (2000) · Neurology · doi:10.1212/wnl.54.9.1805 · Cited by 283
Frontal lobe dysfunction in secondary depression
Mayberg, H. S. (1994) · Journal of Neuropsychiatry · doi:10.1176/jnp.6.4.428 · Cited by 276
Anosognosia in patients with cerebrovascular lesions. A study of causative factors.
STARKSTEIN, S. E., Fedoroff, J. P., Price, T. R., Leiguarda, R. C., & Robinson, R. G. (1992) · Stroke · doi:10.1161/01.str.23.10.1446 · Cited by 262
Fluoxetine in Early Poststroke Depression
Wiart, L., Petit, H., Joseph, P.-A., Mazaux, J., & Barat, M. (2000) · Stroke · doi:10.1161/01.str.31.8.1829 · Cited by 259
Cerebrovascular Disease and Depression Symptoms in the Cardiovascular Health Study
Steffens, D. C., Helms, M. J., Krishnan, K., & Burke, G. L. (1999) · Stroke · doi:10.1161/01.str.30.10.2159 · Cited by 259
Risk factors for post‐stroke depression
Andersen, G., Vestergaard, K., Ingeman‐Nielsen, M., & Lauritzen, L. (1995) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1995.tb09567.x · Cited by 257
Effect of experimental cerebral infarction in rat brain on catecholamines and behaviour
Robinson, R. G., Shoemaker, W. J., Schlumpf, M., VALK, T., & Bloom, F. E. (1975) · Nature · doi:10.1038/255332a0 · Cited by 253
Mood Disorder Following Cerebrovascular Accident
Eastwood, M. R., Rifat, S. L., Nobbs, H., & Ruderman, J. (1989) · The British Journal of Psychiatry · doi:10.1192/bjp.154.2.195 · Cited by 252
Secondary mania with focal cerebrovascular lesions
Cummings, J. L., & Mendez, M. F. (1984) · American Journal of Psychiatry · doi:10.1176/ajp.141.9.1084 · Cited by 250
Incidence of silent cerebral infarction in patients with major depression.
Fujikawa, T., Yamawaki, S., & Touhouda, Y. (1993) · Stroke · doi:10.1161/01.str.24.11.1631 · Cited by 241
A two year longitudinal study of mood disorders following stroke. Prevalence and duration at six months follow-up
Robinson, R. G., Starr, L. B., & Price, T. R. (1984) · The British Journal of Psychiatry · doi:10.1192/bjp.144.3.256 · Cited by 236
Mechanisms of Mania after Brain Injury
STARKSTEIN, S. E., BOSTON, J. D., & Robinson, R. G. (1988) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-198802000-00004 · Cited by 229
The Relationship Between Self‐Rated Health and Depressive Symptoms in an Epidemiological Sample of Community‐Dwelling Older Adults
Mulsant, B. H., Ganguli, M., & Seaberg, E. C. (1997) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1997.tb02966.x · Cited by 229
Self-citation
A two-year longitudinal study of post-stroke mood disorders: dynamic changes in associated variables over the first six months of follow-up.
Robinson, R. G., Starr, L. B., Lipsey, J. R., Rao, K. C. V. G., & Price, T. R. (1984) · Stroke · doi:10.1161/01.str.15.3.510 · Cited by 209
Magnetic Resonance Imaging Correlates of Depression After Ischemic Stroke
Vataja, R., Pohjasvaara, T., Leppävuori, A., Mäntylä, R., Aronen, H. J., Salonen, O. L. M., Kaste, M., & Erkinjuntti, T. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.10.925 · Cited by 207
Silent Cerebral Infarctions in Patients With Late-Onset Mania
Fujikawa, T., Yamawaki, S., & Touhouda, Y. (1995) · Stroke · doi:10.1161/01.str.26.6.946 · Cited by 199
Functional and Neuroanatomic Correlations in Poststroke Depression
Singh, A., Black, S. E., Herrmann, N., Leibovitch, F. S., Ebert, P. L., Lawrence, J., & Szalai, J. P. (2000) · Stroke · doi:10.1161/01.str.31.3.637 · Cited by 195
MRI signal hyperintensities in geriatric depression
GREENWALD, B. S., Kramer‐Ginsberg, E., Krishnan, R. R., Ashtari, M., Aupperle, P. M., & Patel, M. C. (1996) · American Journal of Psychiatry · doi:10.1176/ajp.153.9.1212 · Cited by 187
Frequency, phenomenology and anatomical–clinical correlates of major post-stroke depression
Gainotti, G., Azzoni, A. B. M., & Marra, C. (1999) · The British Journal of Psychiatry · doi:10.1192/bjp.175.2.163 · Cited by 187
Are depressive symptoms nonspecific in patients with acute stroke?
Fedoroff, J. P., STARKSTEIN, S. E., Parikh, R. M., Price, T. R., & Robinson, R. G. (1991) · American Journal of Psychiatry · doi:10.1176/ajp.148.9.1172 · Cited by 183
The significance of affective symptoms in old age
Mink, W. D. (1963) · Psychosomatics · doi:10.1016/s0033-3182(63)73151-3 · Cited by 180
Phenomenological comparison of poststroke depression and functional depression
Lipsey, J. R., Spencer, W. C., Rabins, P. V., & Robinson, R. G. (1986) · American Journal of Psychiatry · doi:10.1176/ajp.143.4.527 · Cited by 176
Clinical depression is associated with impaired recovery from stroke
Morris, P. L. P., Raphael, B., & Robinson, R. G. (1992) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.1992.tb137126.x · Cited by 176
Comparison of Patients With and Without Poststroke Major Depression Matched for Size and Location of Lesion
STARKSTEIN, S. E. (1988) · Archives of General Psychiatry · doi:10.1001/archpsyc.1988.01800270061007 · Cited by 168
Affective Illness After Stroke
Ebrahim, S. B. J., Barer, D. H., & Nouri, F. (1987) · The British Journal of Psychiatry · doi:10.1192/bjp.151.1.52 · Cited by 166
Differential Mood Changes Following Basal Ganglia vs Thalamic Lesions
STARKSTEIN, S. E., Robinson, R. G., Berthier, M. L., Parikh, R. M., & Price, T. R. (1988) · Archives of Neurology · doi:10.1001/archneur.1988.00520310031013 · Cited by 164
Mood Changes After Right-Hemisphere Lesions
STARKSTEIN, S. E., Robinson, R. G., Honig, M. A., Parikh, R. M., Joselyn, J., & Price, T. R. (1989) · The British Journal of Psychiatry · doi:10.1192/bjp.155.1.79 · Cited by 163
On the Inseparability of Mental and Physical Health in Aged Persons Lessons From Depression and Medical Comorbidity
Katz, I. R. (1996) · American Journal of Geriatric Psychiatry · doi:10.1097/00019442-199624410-00001 · Cited by 160
Generalized Anxiety Disorder after Stroke
CASTILLO, C. S., STARKSTEIN, S. E., FEDOROFF, J. P., PRICE, T. R., & ROBINSON, R. G. (1993) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-199302000-00005 · Cited by 159
Manic delirium and frontal-like syndrome with paramedian infarction of the right thalamus.
Bogousslavsky, J., Ferrazzini, M., Regli, F., ASSAL, G., Tanabe, H., & Delaloye-Bischof, A. (1988) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.51.1.116 · Cited by 152
Gender Differences in Poststroke Depression
Paradiso, S., & Robinson, R. G. (1998) · Journal of Neuropsychiatry · doi:10.1176/jnp.10.1.41 · Cited by 143
Longitudinal Assessment of Depression and Cognitive Impairment Following Stroke
Downhill, J. E., & Robinson, R. G. (1994) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-199408000-00001 · Cited by 141
Post-Stroke Depression, Antidepressant Treatment and Rehabilitation Results
Paolucci, S., Antonucci, G., Grasso, M. G., Morelli, D., Troisi, E., Coiro, P., Angelis, D. D., Rizzi, F., & Bragoni, M. (2001) · Cerebrovascular Diseases · doi:10.1159/000047714 · Cited by 137
Brain reserve and the clinical expression of Alzheimer's disease.
Mortimer, J. A. (1997) · PubMed · Cited by 133
Psychological management of post‐stroke depression
Kneebone, I. I., & Dunmore, E. (2000) · British Journal of Clinical Psychology · doi:10.1348/014466500163103 · Cited by 127
Electroconvulsive therapy for poststroke depression.
Gb, M., Shea, V., & Dk, C. (1986) · PubMed · Cited by 122
Functional Impairment Associated With Acute Poststroke Depression
Ramasubbu, R., Robinson, R. G., Flint, A. J., Kosier, T., & Price, T. R. (1998) · Journal of Neuropsychiatry · doi:10.1176/jnp.10.1.26 · Cited by 120
Prevention of poststroke depression: 1 year randomised placebo controlled double blind trial of mianserin with 6 month follow up after therapy
Palomäki, H., Kaste, M., Berg, A., Lönnqvist, R., Lönnqvist, J. K., Lehtihalmes, M., & Hares, J. (1999) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.66.4.490 · Cited by 117
Depressive Disorders in Long-Term Survivors of Stroke
Sharpe, M., Hawton, K. E., Seagroatt, V. A., Bamford, J., House, A. O., Molyneux, A., Sandercock, P. A., & Warlow, C. P. (1994) · The British Journal of Psychiatry · doi:10.1192/bjp.164.3.380 · Cited by 116
Depression and its relation to lesion location after stroke
MacHale, S. M., O’Rourke, S. J., Wardlaw, J. M., & Dennis, M. S. (1998) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.64.3.371 · Cited by 113
Depression, Introversion and Mortality following Stroke
Morris, P., Robinson, R. G., & SAMUELS, J. F. (1993) · Australian & New Zealand Journal of Psychiatry · doi:10.3109/00048679309075801 · Cited by 110
Electroconvulsive therapy for post-stroke depressed geriatric patients
Currier, M. B., Murray, G. B., & Welch, C. C. (1992) · Journal of Neuropsychiatry · doi:10.1176/jnp.4.2.140 · Cited by 110
Relationship Between Anxiety Disorders and Depressive Disorders in Patients With Cerebrovascular Injury
STARKSTEIN, S. E. (1990) · Archives of General Psychiatry · doi:10.1001/archpsyc.1990.01810150046008 · Cited by 108
THE PSYCHOLOGICAL SYMPTOMS OF CONJUGAL BEREAVEMENT IN ELDERLY MEN OVER THE FIRST 13 MONTHS
Byrne, G. J., & Raphael, B. (1997) · International Journal of Geriatric Psychiatry · doi:10.1002/(sici)1099-1166(199702)12:2 · Cited by 106
Depression in stroke rehabilitation
Schwartz, J. A., Speed, N., Brunberg, J. A., Brewer, T. L., Brown, M. B., & Greden, J. F. (1993) · Biological Psychiatry · doi:10.1016/0006-3223(93)90118-w · Cited by 106
Effects of Early Treatment of Poststroke Depression on Neuropsychological Rehabilitation
González-Torrecillas, J. L., Mendiewicz, J., & Lobo, A. (1995) · International Psychogeriatrics · doi:10.1017/s1041610295002286 · Cited by 101
Poststroke Depression in Acute Phase after Stroke
Berg, A., Palomäki, H., Lehtihalmes, M., Lönnqvist, J. K., & Kaste, M. (2001) · Cerebrovascular Diseases · doi:10.1159/000047675 · Cited by 96
Vegetative and Psychological Symptoms Associated with Depressed Mood over the First Two Years after Stroke
Paradiso, S., Ohkubo, T., & Robinson, R. G. (1997) · The International Journal of Psychiatry in Medicine · doi:10.2190/bwja-kqp3-7vuy-d06t · Cited by 94
A study of post‐stroke depression in a rehabilitative center
Ng, K. C., Chan, K.-L., & Straughan, P. T. (1995) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1995.tb09546.x · Cited by 90
Efficacy and side effects of methylphenidate for poststroke depression.
Lazarus, L. W., Winemiller, D. R., Lingam, V. R., Neyman, I., Hartman, C., Abassian, M., Kartan, U., Groves, L., & Fawcett, J. (1992) · PubMed · Cited by 88
Assessment of depression in patients with brain pathology: The case of stroke.
Spencer, K. A., Tompkins, C. A., & Schulz, R. (1997) · Psychological Bulletin · doi:10.1037/0033-2909.122.2.132 · Cited by 87
Two-year longitudinal study of post-stroke mood disorders: comparison of acute-onset with delayed-onset depression
Robinson, R. G., Lipsey, J. R., Rao, K. C. V. G., & Price, T. R. (1986) · American Journal of Psychiatry · doi:10.1176/ajp.143.10.1238 · Cited by 87
The Clinical Psychiatry of Late Life.
(1966) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.1966.tb19524.x · Cited by 85
The Relationship Between Risk Factors for Affective Disorder and Poststroke Depression in Hospitalised Stroke Patients
Morris, P., Robinson, R. G., Raphael, B., SAMUELS, J. F., & Molloy, P. (1992) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/000486749202600204 · Cited by 85
Depressive changes in stroke patients
Herrmann, M., & Wallesch, C. (1993) · Disability and Rehabilitation · doi:10.3109/09638289309165873 · Cited by 81
Depression and Frailty: The Need for Multidisciplinary Research
Katz, I. R. (2004) · American Journal of Geriatric Psychiatry · doi:10.1097/00019442-200401000-00001 · Cited by 80
Post-stroke depression: combined treatment with imipramine or desipramine and mianserin
Lauritzen, L., Bendsen, B. B., Vilmar, T., Bendsen, E. B., Lunde, M., & Bech, P. (1994) · Psychopharmacology · doi:10.1007/bf02245452 · Cited by 76
Suicidal Plans in Patients with Acute Stroke
Kishi, Y., Kosier, J. T., & Robinson, R. G. (1996) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-199605000-00002 · Cited by 73
Methylphenidate and nortriptyline in the treatment of poststroke depression: A retrospective comparison
Lazarus, L. W., Moberg, P. J., Langsley, P. R., & Lingam, V. R. (1994) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/0003-9993(94)90163-5 · Cited by 73
Psychostimulants in post-stroke depression
Masand, P. S., Murray, G. B., & Pickett, P. (1991) · Journal of Neuropsychiatry · doi:10.1176/jnp.3.1.23 · Cited by 72
Poststroke Depression and Anxiety: Different Assessment Methods Result in Variations in Incidence and Severity Estimates
Goldstein, G., Condray, R., Schramke, C. J., Stowe, R., & Ratcliff, G. G. (1998) · Journal of Clinical and Experimental Neuropsychology · doi:10.1076/jcen.20.5.723.1117 · Cited by 70
Background factors and clinical symptoms of major depression with silent cerebral infarction.
Fujikawa, T., Yamawaki, S., & Touhouda, Y. (1994) · Stroke · doi:10.1161/01.str.25.4.798 · Cited by 68
The crucial role of frontostriatal circuits for depressive disorders in the postacute stage after stroke.
Beblo, T., Cw, W., & Herrmann, M. (1999) · PubMed · Cited by 65
Dimensions of Social Impairment and Their Effect on Depression and Recovery Following Stroke
Robinson, R. G., Murata, Y., & 下田, 健. (1999) · International Psychogeriatrics · doi:10.1017/s1041610299005992 · Cited by 63
Suicidal Plans in Patients With Stroke: Comparison Between Acute-Onset and Delayed-Onset Suicidal Plans
Kishi, Y., Robinson, R. G., & Kosier, J. T. (1996) · International Psychogeriatrics · doi:10.1017/s1041610296002931 · Cited by 61
Methylphenidate in treating poststroke depression.
Lingam, V. R., Lw, L., Groves, L., & Oh, S. H. (1988) · PubMed · Cited by 60
Anosognosia and major depression in 2 patients with cerebrovascular lesions
STARKSTEIN, S. E., Berthier, M. L., Fedoroff, P., Price, T. R., & Robinson, R. G. (1990) · Neurology · doi:10.1212/wnl.40.9.1380 · Cited by 58
METHYLPHENIDATE IN STROKE PATIENTS WITH DEPRESSION
Johnson, M. L., Roberts, M. D., Ross, A. R., & Witten, C. M. (1992) · American Journal of Physical Medicine & Rehabilitation · doi:10.1097/00002060-199208000-00008 · Cited by 54
Poststroke bipolar affective disorder: clinical subtypes, concurrent movement disorders, and anatomical correlates
Berthier, M. L., Kulisevsky, J., Gironell, A., & Benitez, J. A. F. (1996) · Journal of Neuropsychiatry · doi:10.1176/jnp.8.2.160 · Cited by 52
Depression associated with stroke
House, A. O. (1996) · Journal of Neuropsychiatry · doi:10.1176/jnp.8.4.453 · Cited by 52
Depression after stroke: the importance of cerebral hemisphere asymmetries
STARKSTEIN, S. E., Bryer, J. B., Berthier, M. L., Cohen, B., Price, T. R., & Robinson, R. G. (1991) · Journal of Neuropsychiatry · doi:10.1176/jnp.3.3.276 · Cited by 51
Are There Two Depressive Syndromes after Stroke?
Morris, P., Shields, R. B., Hopwood, M., Robinson, R. G., & Raphael, B. (1994) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-199404000-00007 · Cited by 48
Major life events as risk factors for post-stroke depression
Bush, B. A. (1999) · Brain Injury · doi:10.1080/026990599121791 · Cited by 44
Hemiballismus and secondary mania following a right thalamic infarction
Kulisevsky, J., Berthier, M. L., & Pujol, J. (1993) · Neurology · doi:10.1212/wnl.43.7.1422 · Cited by 41
Personality Neuroticism and Depression after Stroke
Morris, P. L. P., & Robinson, R. G. (1995) · The International Journal of Psychiatry in Medicine · doi:10.2190/e25j-bcqb-bmem-gy9f · Cited by 34
The Relationship Between Risk Factors for Affective Disorder and Poststroke Depression in Hospitalised Stroke Patients
Morris, P., Robinson, R. A., Raphael, B., et al. (1992) · Australian & New Zealand Journal of Psychiatry · doi:10.3109/00048679209072029 · Cited by 34
Does Stroke Cause Depression?
Lyketsos, C. G., Treisman, G. J., Lipsey, J. R., Morris, P., & Robinson, R. G. (1998) · Journal of Neuropsychiatry · doi:10.1176/jnp.10.1.103 · Cited by 33
Mood Disorders Secondary to Stroke.
Robinson, R. (1997) · PubMed · doi:10.1053/scnp00200244 · Cited by 29
Therapy of Early Poststroke Depression With Venlafaxine: Safety, Tolerability, and Efficacy as Determined in an Open, Uncontrolled Clinical Trial
Dahmen, N., Marx, J., Hopf, H. C., Tettenborn, B., & Röder, R. (1999) · Stroke · doi:10.1161/01.str.30.3.691 · Cited by 29
Characterization of elderly patients in rehabilitation: stroke versus hip fracture
Lieberman, D., Friger, M. D., Fried, V., Grinshpun, Y., Mytlis, N., Tylis, R., Galinsky, D., & Lieberman, D. B. (1999) · Disability and Rehabilitation · doi:10.1080/096382899297198 · Cited by 28
The significance of affective symptoms in old age : a follow-up study of one hundred patients
Post, F. (1962) · Oxford University Press eBooks · Cited by 24
Poststroke depression and fluoxetine
Stamenkovic, M., Schindler, S., & Kasper, S. F. (1996) · American Journal of Psychiatry · doi:10.1176/ajp.153.3.446b · Cited by 21
Poststroke depression and emotional incontinence
Spalletta, G., Angelis, D. D., & Caltagirone, C. (2000) · Neurology · doi:10.1212/wnl.55.11.1760-a · Cited by 17
Untitled work
(1998) · doi:10.1002/(sici)1099-1166(199805)13:5

Research works printed but not linked: 1

Alexopoulos G, Kiosses D, Choi S, Murphy C, Lim K (in press) Microanatomy of Treatment Response in Late Life Depression: A Preliminary Study. Am J Psych

Sorted by citations

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Katon, W. J. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00273-7 · Cited by 1,248
Poststroke Depression: A Scientific Statement for Healthcare Professionals From the American Heart Association/American Stroke Association
Towfighi, A., Ovbiagele, B. I., Husseini, N. E., Hackett, M. L., Jorge, R. E., D, B. M. K. M., Mitchell, P. H., Skolarus, L. E., Whooley, M. A., & Williams, L. S. (2016) · Stroke · doi:10.1161/str.0000000000000113 · Cited by 824
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Clarke, D. M., & Currie, K. C. (2009) · Medical Journal of Australia · doi:10.5694/j.1326-5377.2009.tb02471.x · Cited by 661
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Geyh, S., Cieza, A., Schouten, J., Dickson, H. G., Frommelt, P., Omar, Z., Kostanjsek, N. F. I., Ring, H., & Stucki, G. (2004) · Journal of Rehabilitation Medicine · doi:10.1080/16501960410016776 · Cited by 462
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See all 488

Authors: Whyte, E. M., & Mulsant, B. H.
Affiliations: University of Pittsburgh (US)
Corresponding author: Mulsant, Benoit H
ORCID: Mulsant, Benoit H
Venue: Biological Psychiatry
Publisher: Elsevier BV
Published: 2002-08
Volume: 52
Issue: 3
Pages: 253-264
ISSN: 0006-3223 (ISSN-L)
DOI: 10.1016/s0006-3223(02)01424-5
OpenAlex: W2070191749
Cited by: 488
References: 126
Citations by year: 2026: 8 · 2025: 19 · 2024: 14 · 2023: 11 · 2022: 21 · 2021: 19 · 2020: 20 · 2019: 25 · 2018: 19 · 2017: 21 · 2016: 41 · 2015: 34 · 2014: 27 · 2013: 32 · 2012: 16
FWCI: 2.65
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Biological Psychiatry (publishedVersion)
PubMed (publishedVersion)
Funders: U.S. Public Health Service (MH01613, T32 MH19986)
Topics: Health Sciences › Medicine › Rehabilitation › Stroke Rehabilitation and Recovery
Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
Life Sciences › Neuroscience › Neurology › Transcranial Magnetic Stimulation Studies
Keywords: post-stroke depression, stroke, depression prevalence, etiology, pathophysiology, biological treatment, biopsychosocial model, cognitive impairment, disability, mortality
MeSH terms: Aged, Antidepressive Agents, Depressive Disorder, Major, Major Depressive Disorder, Humans, Time Factors, Stroke

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Post stroke depression: epidemiology, pathophysiology, and biological treatment

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