Peroxynitrite-induced myocardial injury is mediated through matrix metalloproteinase-2

Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide

Beckman, J. S., Beckman, T. W., Chen, J., Marshall, P. A., & Freeman, B. A. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.4.1620 · Cited by 7,029 · see citing works

Matrix Metalloproteinases

Nagase, H., & Woessner, J. F. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.31.21491 · Cited by 3,905 · see citing works

Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques.

Galis, Z. S., Sukhova, G. K., Lark, M. W., & Libby, P. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117619 · Cited by 2,537 · see citing works

Peroxynitrite oxidation of sulfhydryls.

Radí, R., Beckman, J. S., Bush, K., & Freeman, B. Α. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)64313-7 · Cited by 2,499 · see citing works

The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family.

Van Wart, H. E., & Birkedal-Hansen, H. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.14.5578 · Cited by 1,475 · see citing works

Nitric oxide regulation of superoxide and peroxynitrite-dependent lipid peroxidation. Formation of novel nitrogen-containing oxidized lipid derivatives

Rubbo, H., Radí, R., Trujillo, M., Telleri, R., Kalyanaraman, B., Barnes, S., KIRK, M. C., & Freeman, B. Α. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)47160-8 · Cited by 1,350 · see citing works

Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stability.

Rajagopalan, S., Meng, X. P., Ramasamy, S., Harrison, D. G., & Galis, Z. S. (1996) · Journal of Clinical Investigation · doi:10.1172/jci119076 · Cited by 1,137 · see citing works

Inflammation Dampened by Gelatinase A Cleavage of Monocyte Chemoattractant Protein-3

McQuibban, G. A., Gong, J.-H., Tam, E. M., McCulloch, C. A., Clark‐Lewis, I., & Overall, C. M. (2000) · Science · doi:10.1126/science.289.5482.1202 · Cited by 772 · see citing works

Inhibition of Mitochondrial Electron Transport by Peroxynitrite

Radi, R., Rodriguez, M., Castro, L., & Telleri, R. (1994) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1994.1013 · Cited by 693 · see citing works

Superoxide and peroxynitrite inatherosclerosis.

White, C. R., Brock, T. A., Chang, L. Y., Crapo, J. D., BRISCOE, P. M., Ku, D. D., Bradley, W. A., Gianturco, S. H., Gore, J. Z., & Freeman, B. Α. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.3.1044 · Cited by 685 · see citing works

Peroxynitrite‐mediated oxidative protein modifications

Ischiropoulos, H., & Al‐Mehdi, A. B. (1995) · FEBS Letters · doi:10.1016/0014-5793(95)00307-u · Cited by 610 · see citing works

Measurement of Nitric Oxide and Peroxynitrite Generation in the Postischemic Heart

Wang, P., & Zweier, J. L. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.46.29223 · Cited by 538 · see citing works

Regulation of collagen degradation in the rat myocardium after infarction

Cleutjens, J. P. M., Kandala, J. C., Guarda, E., et al. (1995) · Journal of Molecular and Cellular Cardiology · doi:10.1016/s0022-2828(05)82390-9 · Cited by 481 · see citing works

Matrix Metalloproteinase-2 Contributes to Ischemia-Reperfusion Injury in the Heart

Cheung, P., Sawicki, G., Woźniak, M., Wang, W., Radomski, M. W., & Schulz, R. (2000) · Circulation · doi:10.1161/01.cir.101.15.1833 · Cited by 431 · see citing works

Vascular Matrix Metalloproteinase-2 Cleaves Big Endothelin-1 Yielding a Novel Vasoconstrictor

Fernández-Patrón, C., Radomski, M. W., & Davidge, S. T. (1999) · Circulation Research · doi:10.1161/01.res.85.10.906 · Cited by 366 · see citing works

Paradoxical fate and biological action of peroxynitrite on human platelets.

Moro, M. Á., Darley-Usmar, V. M., Goodwin, D. A., Read, N. G., Zamora-Pino, R., Feelisch, M., Radomski, M. W., & Moncada, S. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.14.6702 · Cited by 363 · see citing works

Release of gelatinase A during platelet activation mediates aggregation

Sawicki, G., Salas, E., Murat, J., et al. (1997) · Nature · doi:10.1038/386616a0 · Cited by 350 · see citing works

Generation of peroxynitrite contributes to ischemia-reperfusion injury in isolated rat hearts

Yasmin, W. M. (1997) · Cardiovascular Research · doi:10.1016/s0008-6363(96)00254-4 · Cited by 343 · see citing works

Peroxynitrite induces both vasodilatation and impaired vascular relaxation in the isolated perfused rat heart.

Villa, L. M., Salas, E., Darley-Usmar, V. M., Radomski, M. W., & Moncada, S. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.26.12383 · Cited by 291 · see citing works

Inactivation of .alpha.1-proteinase inhibitor by peroxynitrite

Moreno, J. J., & Pryor, W. A. (1992) · Chemical Research in Toxicology · doi:10.1021/tx00027a017 · Cited by 250 · see citing works

Cardiac Peroxynitrite Formation and Left Ventricular Dysfunction following Doxorubicin Treatment in Mice

Weinstein, D. M., Mihm, M. J., & Bauer, J. A. (2000) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)39082-2 · Cited by 227 · see citing works

Activation of Human Neutrophil Procollagenase by Nitrogen Dioxide and Peroxynitrite: A Novel Mechanism for Procollagenase Activation Involving Nitric Oxide

Okamoto, T., Akaike, T., Nagano, T., Miyajima, S., Suga, M., Ando, M., Ichimori, K., & Maeda, H. (1997) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1997.0127 · Cited by 224 · see citing works

Cytokine-Mediated Apoptosis in Cardiac Myocytes

Arstall, M. A., Sawyer, D. B., Fukazawa, R., & Kelly, R. A. (1999) · Circulation Research · doi:10.1161/01.res.85.9.829 · Cited by 220 · see citing works

Partial purification of collagenase and gelatinase from human polymorphonuclear leucocytes. Analysis of their actions on soluble and insoluble collagens

Murphy, G., Reynolds, J. J., Bretz, U., et al. (1982) · Biochemical Journal · doi:10.1042/bj2030209 · Cited by 200 · see citing works

The formation of nitric oxide donors from peroxynitrite

Moro, M. Á., Darley-Usmar, V. M., Lizasoaín, I., Su, Y., Knowles, R. G., Moncada, S., & Radomski, M. W. (1995) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1995.tb16404.x · Cited by 197 · see citing works

The cardiovascular effects and implications of peroxynitrite

Ronson, R. S. (1999) · Cardiovascular Research · doi:10.1016/s0008-6363(99)00184-4 · Cited by 191 · see citing works

Vascular Matrix Metalloproteinase-2–Dependent Cleavage of Calcitonin Gene-Related Peptide Promotes Vasoconstriction

Fernández-Patrón, C., Stewart, K., Zhang, Y., Koivunen, E., Radomski, M. W., & Davidge, S. T. (2000) · Circulation Research · doi:10.1161/01.res.87.8.670 · Cited by 175 · see citing works

Inactivation of tissue inhibitor of metalloproteinase‐1 by peroxynitrite

Frears, E. R., Zhang, Z., Blake, D. R., O’Connell, J. P., & Winyard, P. G. (1996) · FEBS Letters · doi:10.1016/0014-5793(96)00065-8 · Cited by 169 · see citing works

N -Acetyl-Cysteine Decreases the Matrix-Degrading Capacity of Macrophage-Derived Foam Cells

Galis, Z. S., Asanuma, K., Godin, D., & Meng, X. (1998) · Circulation · doi:10.1161/01.cir.97.24.2445 · Cited by 159 · see citing works

Autocrine inhibition of Na+/K(+)-ATPase by nitric oxide in mouse proximal tubule epithelial cells.

Guzman, N. J., Fang, M., Tang, S., Ingelfinger, J. R., & Garg, L. C. (1995) · Journal of Clinical Investigation · doi:10.1172/jci117895 · Cited by 157 · see citing works

Peroxynitrite Causes Apoptosis in Rat Thymocytes

Salgo, M. G., Squadrito, G. L., & PRYOR, W. A. (1995) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1995.2578 · Cited by 150 · see citing works

Nitric Oxide Contributes to the Progression of Myocardial Damage in Experimental Autoimmune Myocarditis in Rats

Ishiyama, S., Hiroe, M., Nishikawa, T., Abe, S., Shimojo, T., Ito, H., Ozasa, S., Yamakawa, K., Matsuzaki, M., Mohammed, M. U., et al. (1997) · Circulation · doi:10.1161/01.cir.95.2.489 · Cited by 141 · see citing works

Altered Balance Between Matrix Gelatinases (MMP-2 and MMP-9) and Their Tissue Inhibitors in Human Dilated Cardiomyopathy: Potential Role of MMP-9 in Myosin-Heavy Chain Degradation

Rouet‐Benzineb, P., Buhler, J., Dreyfus, P. A., et al. (1999) · European Journal of Heart Failure · doi:10.1016/s1388-9842(99)00048-3 · Cited by 139 · see citing works

Purification of a Type V Collagen Degrading Metalloproteinase from Rabbit Alveolar Macrophages

Mainardi, C. L., Hibbs, M. S., Hasty, K. A., et al. (1984) · Collagen and Related Research · doi:10.1016/s0174-173x(84)80014-x · Cited by 98 · see citing works

Peroxynitrite aggravates myocardial reperfusion injury in the isolated perfused rat heart

Ma, X. (1997) · Cardiovascular Research · doi:10.1016/s0008-6363(97)00179-x · Cited by 81 · see citing works

Glutathione Protects Against Myocardial Ischemia–reperfusion Injury by Detoxifying Peroxynitrite

Cheung, P., Wang, W., & Schulz, R. (2000) · Journal of Molecular and Cellular Cardiology · doi:10.1006/jmcc.2000.1203 · Cited by 65 · see citing works

Effects of reactive metabolites of oxygen and nitrogen on gelatinase A activity

Owens, M. W., Milligan, S. A., Jourd’heuil, D., et al. (1997) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.1997.273.2.l445 · Cited by 59 · see citing works

Structural remodelling in heart failure: gelatinase induction.

Armstrong, P. W., Gw, M., Howard, R. J., et al. (1994) · PubMed · Cited by 59 · see citing works

Thiols Protect the Inhibition of Myocardial Aconitase by Peroxynitrite

Cheung, P., Danial, H., Jong, J., & Schulz, R. (1998) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1997.0496 · Cited by 54 · see citing works

QUANTITATIVE ANALYSIS OF CARDIAC 3-L-NITROTYROSINE DURING ACUTE ALLOGRAFT REJECTION IN AN EXPERIMENTAL HEART TRANSPLANTATION1

Sakurai, M., Fukuyama, N., Iguchi, A., Akimoto, H., OHMI, M., Yokoyama, H., Nakazawa, H. K., & Tabayashi, K. (1999) · Transplantation · doi:10.1097/00007890-199912150-00031 · Cited by 20 · see citing works

Glutathione causes coronary vasodilation via a nitric oxide- and soluble guanylate cyclase-dependent mechanism

Cheung, P., & Schulz, R. (1997) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1997.273.3.h1231 · Cited by 20 · see citing works

Quantitative analysis

(2017) · Oxbow Books · doi:10.2307/j.ctvh1dv4w.8 · Cited by 5 · see citing works

Nitric Oxide and Peroxynitrite in Health and Disease

Pacher, P., Beckman, J. S., & Liaudet, L. (2007) · Physiological Reviews · doi:10.1152/physrev.00029.2006 · Cited by 6,390 · see citing works

Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation

Tejero, J., Shiva, S., & Gladwin, M. T. (2019) · Physiological Reviews · doi:10.1152/physrev.00036.2017 · Cited by 541 · see citing works

Nitric oxide and nitric oxide synthase isoforms in the normal, hypertrophic, and failing heart

Umar, S., & van der Laarse, A. (2010) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-009-0219-x · Cited by 182 · see citing works

Zymographical Techniques for Detectionof Matrix Metalloproteinases

Iwai, S., Nakanishi‐Ueda, T., Armstrong, D., et al. (2008) · Methods in molecular biology · doi:10.1007/978-1-60327-517-0_10 · Cited by 7 · see citing works

Analysis of Enzymatic Activity of Matrix Metalloproteinase (MMP) by Collagen Zymography in Melanoma

Walia, V., & Samuels, Y. (2018) · Methods in molecular biology · doi:10.1007/978-1-4939-7595-2_10 · Cited by 5 · see citing works

Imbalance between matrix metalloproteinases and tissue inhibitor of metalloproteinases in hypertensive vascular remodeling

de Castro, M. M., Rizzi, É., Prado, C. M., et al. (2009) · Matrix Biology · doi:10.1016/j.matbio.2009.11.005 · Cited by 117 · see citing works

Zymographic Techniques for the Analysis of Matrix Metalloproteinases and their Inhibitors

Snoek, P. A. M., & den Hoff, J. W. V. (2005) · BioTechniques · doi:10.2144/05381rv01 · Cited by 526 · see citing works

Detection of Matrix Metalloproteinases by Zymography

Tajhya, R. B., Patel, R. S., & Beeton, C. (2017) · Methods in molecular biology · doi:10.1007/978-1-4939-6863-3_12 · Cited by 61 · see citing works