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Olive oil phenolics are dose‐dependently absorbed in humans
Abstract
Olive oil phenolic constituents have been shown, in vitro, to be endowed with potent biological activities including, but not limited to, an antioxidant action. To date, there is no information on the absorption and disposition of such compounds in humans. We report that olive oil phenolics, namely tyrosol and hydroxytyrosol, are dose‐dependently absorbed in humans after ingestion and that they are excreted in the urine as glucuronide conjugates. Furthermore, an increase in the dose of phenolics administered increased the proportion of conjugation with glucuronide.
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Citations
Cited by
By-products of plant food processing as a source of functional compounds—Recent developments
Schieber, A., Stintzing, F. C., & Carle, R. (2001) · Trends in Food Science & Technology · doi:10.1016/s0924-2244(02)00012-2 · Cited by 1,334
Dietary polyphenols and their biological significance
Han, X., Shen, T., & Lou, H. (2007) · International Journal of Molecular Sciences · doi:10.3390/i8090950 · Cited by 1,081
“Hydroxytyrosol, the major olive oil phenolic compound, is dosedependently absorbed from olive oil [195].”
BackgroundBioavailability of the polyphenols: Status and controversies
D’Archivio, M., Filesi, C., Varì, R., Scazzocchio, B., & Masella, R. (2010) · International Journal of Molecular Sciences · doi:10.3390/ijms11041321 · Cited by 950
Bendini, A., Cerretani, L., Carrasco-Pancorbo, A., Gómez-Caravaca, A. M., Segura-Carretero, A., Fernández-Gutiérrez, A., & Lercker, G. (2007) · Molecules · doi:10.3390/12081679 · Cited by 784
Major phenolic compounds in olive oil: metabolism and health effects
Tuck, K. L., & Hayball, P. J. (2002) · The Journal of Nutritional Biochemistry · doi:10.1016/s0955-2863(02)00229-2 · Cited by 705
Metadata
- Authors
- Visioli, F., Galli, C., Bornet, F., Mattei, A., Patelli, R., Galli, G., & Caruso, D.
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 2000-02-22
- Volume
- 468
- Issue
- 2-3
- Pages
- 159-160
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W2026701024
- Cited by
- 378
- References
- 0
- FWCI
- 16.56
- Type
- journal article
- Language
- en
- Open access
- closed
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- Visioli, F., Galli, C., Bornet, F., Mattei, A., Patelli, R., Galli, G., & Caruso, D. (2000). Olive oil phenolics are dose‐dependently absorbed in humans. FEBS Letters. https://doi.org/10.1016/s0014-5793(00)01216-3
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
