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Cited by 351

The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.

A novel reporter mouse strain that expresses enhanced green fluorescent protein upon Cre‐mediated recombination

Open access
Kawamoto, Shunsuke, Niwa, Hitoshi, Tashiro, Fumi, Sano, Shigetoshi, Kondoh, Gen, Takeda, Junji, Tabayashi, Koichi, Miyazaki, Jun-ichi·2000·FEBS Letters

Abstract

The success of Cre‐mediated conditional gene targeting depends on the specificity of Cre recombinase expression in Cre‐transgenic mouse lines. As a tool to evaluate the specificity of Cre expression, we developed a reporter transgenic mouse strain that expresses enhanced green fluorescent protein (EGFP) upon Cre‐mediated recombination. We demonstrate that the progeny resulting from a cross between this reporter strain and a transgenic strain expressing Cre in zygotes show ubiquitous EGFP fluorescence. This reporter strain should be useful to monitor the Cre expression directed by various promoters in transgenic mice, including mice in which Cre is expressed transiently during embryogenesis under a developmentally regulated promoter.

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Metadata

Authors
Kawamoto, S., Niwa, H., Tashiro, F., Sano, S., Kondoh, G., Takeda, J., Tabayashi, K., & Miyazaki, J.-I.
Venue
FEBS Letters
Publisher
Wiley
Published
2000-03-27
Volume
470
Issue
3
Pages
263-268
ISSN
  • 0014-5793 (ISSN-L)
  • 1873-3468
OpenAlex
W2008009288
Cited by
351
References
13
FWCI
4.82
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: A novel reporter mouse strain that expresses enhanced green fluorescent protein upon Cre‐mediated recombination. https://app.cochat.ai/papers/10.1016/s0014-5793(00)01338-7
The paper
Kawamoto, S., Niwa, H., Tashiro, F., Sano, S., Kondoh, G., Takeda, J., Tabayashi, K., & Miyazaki, J.-I. (2000). A novel reporter mouse strain that expresses enhanced green fluorescent protein upon Cre‐mediated recombination. FEBS Letters. https://doi.org/10.1016/s0014-5793(00)01338-7

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