The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Base excision repair of DNA in mammalian cells
Open accessAbstract
Base excision repair (BER) of DNA corrects a number of spontaneous and environmentally induced genotoxic or miscoding base lesions in a process initiated by DNA glycosylases. An AP endonuclease cleaves at the 5′ side of the abasic site and the repair process is subsequently completed via either short patch repair or long patch repair, which largely require different proteins. As one example, the UNG gene encodes both nuclear (UNG2) and mitochondrial (UNG1) uracil DNA glycosylase and prevents accumulation of uracil in the genome. BER is likely to have a major role in preserving the integrity of DNA during evolution and may prevent cancer.
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Citations
Cites
Instability and decay of the primary structure of DNA
Lindahl, T. (1993) · Nature · doi:10.1038/362709a0 · Cited by 5,679
Cited by
How nucleotide excision repair protects against cancer
Friedberg, E. C. (2001) · Nature Reviews Cancer · doi:10.1038/35094000 · Cited by 730
Defying death after DNA damage
Rich, T., Allen, R. L., & Wyllie, A. H. (2000) · Nature · doi:10.1038/35037717 · Cited by 724
Base excision repair and cancer
Wallace, S. S., Murphy, D. L., & Sweasy, J. B. (2012) · Cancer Letters · doi:10.1016/j.canlet.2011.12.038 · Cited by 329
Replication Protein A phosphorylation and the cellular response to DNA damage
Binz, S. K., Sheehan, A. M., & Wold, M. S. (2004) · DNA Repair · doi:10.1016/j.dnarep.2004.03.028 · Cited by 299
Schrem, H., Klempnauer, J., & Borlak, J. (2002) · Pharmacological Reviews · doi:10.1124/pr.54.1.129 · Cited by 283
Metadata
- Authors
- Krokan, H. E., Nilsen, H., Skorpen, F., Otterlei, M., & Slupphaug, G.
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 2000-06-26
- Volume
- 476
- Issue
- 1-2
- Pages
- 73-77
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W1970566518
- Cited by
- 371
- References
- 1
- FWCI
- 7.44
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Krokan, H. E., Nilsen, H., Skorpen, F., Otterlei, M., & Slupphaug, G. (2000). Base excision repair of DNA in mammalian cells. FEBS Letters. https://doi.org/10.1016/s0014-5793(00)01674-4
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
