The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Interaction domains: from simple binding events to complex cellular behavior
Open accessAbstract
Many of the signaling pathways and regulatory systems in eukaryotic cells are controlled by proteins with multiple interaction domains that mediate specific protein–protein and protein–phospholipid interactions, and thereby determine the biological output of receptors for external and intrinsic signals. Here, we discuss the basic features of interaction domains, and suggest that rather simple binary interactions can be used in sophisticated ways to generate complex cellular responses.
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Jaakkola, P., Mole, D. R., Tian, Y.-M., Wilson, M. I., Gielbert, J., Gaskell, S. J., Kriegsheim, A. V., Hebestreit, H. F., Mukherji, M., Schofield, C. J., et al. (2001) · Science · doi:10.1126/science.1059796 · Cited by 5,535
HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O 2 Sensing
Ivan, M., Kondo, K., Yang, H., Kim, W., Valiando, J., Ohh, M., Salic, A., Asara, J. M., Lane, W. S., & Kaelin Jr., W. G. (2001) · Science · doi:10.1126/science.1059817 · Cited by 4,735
Protein modules and signalling networks
Pawson, T. (1995) · Nature · doi:10.1038/373573a0 · Cited by 2,420
Self-citationRecognition of Unique Carboxyl-Terminal Motifs by Distinct PDZ Domains
Songyang, Z., Fanning, A. S., Fu, C., Xu, J., Marfatia, S. M., Chishti, A. H., Crompton, A., Chan, A. C., Anderson, J. M., & Cantley, L. C. (1997) · Science · doi:10.1126/science.275.5296.73 · Cited by 1,385
Specific and high-affinity binding of inositol phosphates to an isolated pleckstrin homology domain
Lemmon, M. A., Ferguson, K. M., O'Brien, R., Sigler, P. B., & Schlessinger, J. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.23.10472 · Cited by 566
Groves, M. R., Hanlon, N., Turowski, P., Hemmings, B. A., & Barford, D. (1999) · Cell · doi:10.1016/s0092-8674(00)80963-0 · Cited by 442
14-3-3 proteins; bringing new definitions to scaffolding
Tzivion, G., Shen, Y. H., & Zhu, J. (2001) · Oncogene · doi:10.1038/sj.onc.1204777 · Cited by 300
Cited by
Sumimoto, H. (2008) · The FEBS Journal · doi:10.1111/j.1742-4658.2008.06488.x · Cited by 721
Dynamic interactions between 14-3-3 proteins and phosphoproteins regulate diverse cellular processes
MACKINTOSH, C. (2004) · Biochemical Journal · doi:10.1042/bj20031332 · Cited by 526
Ojida, A., Mito-oka, Y., Sada, K., & Hamachi, I. (2004) · Journal of the American Chemical Society · doi:10.1021/ja038277x · Cited by 366
Residues neighboring an SH3-binding motif participate in the interaction in vivo
Jordan, D. F., Dubé, A. K., Dionne, U., Bradley, D., & Landry, C. R. (2025) · GENETICS · doi:10.1093/genetics/iyaf153
Metadata
- Authors
- Pawson, T., Raina, M., & Nash, P.
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 2001-12-20
- Volume
- 513
- Issue
- 1
- Pages
- 2-10
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W2015961921
- Cited by
- 159
- References
- 7
- FWCI
- 4.67
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
