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Growth phase‐dependent changes in the subcellular localization of pre‐B‐cell colony‐enhancing factor1
Abstract
A cDNA encoding the homolog of the human pre‐B‐cell colony‐enhancing factor (PBEF), a cytokine‐like secreted protein, was isolated from a rat cDNA library. This protein existed in both the cytoplasm and nucleus of the cells, and the amount was higher in the cytoplasm than in the nucleus of proliferating PC‐12 and Swiss 3T3 cells but higher in the nucleus than in the cytoplasm of the PC‐12 cells treated with nerve growth factor and the 3T3 cells grown to a confluent state. Thus, the so‐called PBEF is not a cytokine‐like secreted protein but an intracellular protein associated with the cell cycle.
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Cited by
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Revollo, J. R., Grimm, A. A., & Imai, S.-I. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m408388200 · Cited by 1,010
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Yang, H., Yang, T., Baur, J. A., Perez, E., Matsui, T., Carmona, J. J., Lamming, D. W., Souza-Pinto, N. C., Bohr, V. A., Rosenzweig, A., et al. (2007) · Cell · doi:10.1016/j.cell.2007.07.035 · Cited by 950
Visfatin, an Adipocytokine with Proinflammatory and Immunomodulating Properties
Moschen, A. R., Kaser, A., Enrich, B., Mosheimer, B., Theurl, M., Niederegger, H., & Tilg, H. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.178.3.1748 · Cited by 933
The secret life of NAD+: an old metabolite controlling new metabolic signaling pathways
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Metadata
- Authors
- Kitani, T., Okuno, S., & Fujisawa, H.
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 2003-05-14
- Volume
- 544
- Issue
- 1-3
- Pages
- 74-78
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W1517721841
- Cited by
- 170
- References
- 0
- FWCI
- 3.32
- Type
- journal article
- Language
- en
- Open access
- closed
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- Kitani, T., Okuno, S., & Fujisawa, H. (2003). Growth phase‐dependent changes in the subcellular localization of pre‐B‐cell colony‐enhancing factor1. FEBS Letters. https://doi.org/10.1016/s0014-5793(03)00476-9
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
