The DOI matches its Crossref record; 12 of the 13 references it cites were found in a registry or an index.
Lipid peroxidation in skeletal muscle of obese as compared to endurance-trained humans: a case of good vs. bad lipids?
Open accessAbstract
Intra-myocellular triglycerides (IMTG) accumulate in the muscle of obese and endurance-trained (ET) humans and are considered a pathogenic factor in the development of insulin resistance, in the former. We postulate that this paradox may be associated with the peroxidation status of the IMTG. IMTG content was the same in the obese and ET subjects. The lipid peroxidation/IMTG ratio was 4.2-fold higher in the obese subjects. Hence, obesity results in an increased level of IMTG peroxidation while ET has a protective effect on IMTG peroxidation. This suggests a link between the lipid peroxidation/IMTG ratio and insulin resistance.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“despite obese insulin resistant subject presenting similar amount of intracellular triglycerides as endurance athletes, the degree of lipid peroxidation was 4.2-fold higher in obese insulin resistant individuals than endurance athletes (Russell et al., 2003)”
From Mitochondrial (Dys)function and Insulin Resistance: From Pathophysiological Molecular Mechanisms to the Impact of Diet (2019) · cites this paper as Russell et al., 2003
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Glass, C. K., & Witztum, J. L. (2001) · Cell · doi:10.1016/s0092-8674(01)00238-0 · Cited by 3,094
Goodpaster, B. H. (2001) · Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.86.12.5755 · Cited by 1,194
Kelley, D. E., Goodpaster, B., Wing, R. R., & Simoneau, J.-A. (1999) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1999.277.6.e1130 · Cited by 1,096
Perseghin, G., Scifo, P., De Cobelli, F., Pagliato, E., Battezzati, A., Arcelloni, C., Vanzulli, A., Testolin, G., Pozza, G., Del Maschio, A., et al. (1999) · Diabetes · doi:10.2337/diabetes.48.8.1600 · Cited by 877
Oxidants and antioxidants in exercise
Sen, C. K. (1995) · Journal of Applied Physiology · doi:10.1152/jappl.1995.79.3.675 · Cited by 621
Palinski, W., Ylä‐Herttuala, S., Rosenfeld, M. E., Butler, S. W., Socher, S. S., Parthasarathy, S., Curtiss, L. K., & Witztum, J. L. (1990) · Arteriosclerosis An Official Journal of the American Heart Association Inc · doi:10.1161/01.atv.10.3.325 · Cited by 616
Intramuscular lipid content is increased in obesity and decreased by weight loss
Goodpaster, B. H., Theriault, R., Watkins, S. C., & Kelley, D. E. (2000) · Metabolism · doi:10.1016/s0026-0495(00)80010-4 · Cited by 526
Dandona, P., Mohanty, P., Ghanim, H., Aljada, A., Browne, R. W., Hamouda, W., Prabhala, A., Afzal, A., & Garg, R. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.1.7150 · Cited by 397
Heterogeneity of pig intestinal d-glucose transport systems
Halaihel, N., Gerbaud, D., Vasseur, M., & Alvarado, F. (1999) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1999.277.6.c1130 · Cited by 199
Macdonald, G. A., Bridle, K. R., Ward, P. J., Walker, N. I., Houglum, K., George, D. K., Smith, J. L., Powell, L. W., Crawford, D. H., & Ramm, G. A. (2001) · Journal of Gastroenterology and Hepatology · doi:10.1046/j.1440-1746.2001.02445.x · Cited by 156
Russell, A. P., Wadley, G. D., Hesselink, M. K. C., Schaart, G., Lo, S. K., Léger, B., GARNHAM, A. P., Moonen‐Kornips, E., Cameron‐Smith, D., Giacobino, J., et al. (2003) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-002-0943-5 · Cited by 72
Antioxidant Vitamin Levels in Plasma and Low Density Lipoprotein of Obese Girls
Kljno, T., Hozumi, M., Morinobu, T., Murata, T., Mingci, Z., & Tamai, H. (1998) · Free Radical Research · doi:10.3109/10715769809097878 · Cited by 59
Research works printed but not linked: 2
- 10.1210/jcem.86.12.8075 · DOI · Paper page
- 10.1210/jc.86.1.355 · DOI
Cited by
Sorted by citations
Halliwell, B., & Whiteman, M. (2004) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0705776 · Cited by 2,238
Manna, P., & Jain, S. K. (2015) · Metabolic Syndrome and Related Disorders · doi:10.1089/met.2015.0095 · Cited by 1,211
Adipose tissue and insulin resistance in obese
Ahmed, B., Sultana, R., & Greene, M. W. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.111315 · Cited by 1,162
Oxidative stress and metabolic syndrome
Roberts, C. K., & Sindhu, K. K. (2009) · Life Sciences · doi:10.1016/j.lfs.2009.02.026 · Cited by 883
Sivitz, W. I., & Yorek, M. A. (2010) · Antioxidants & Redox Signaling · doi:10.1089/ars.2009.2531 · Cited by 742
Metadata
- Authors
- Russell, A. P., Gastaldi, G., Bobbioni-Harsch, E., Arboit, P., Gobelet, C., Dériaz, O., Golay, A., Witztum, J. L., & Giacobino, J.-P.
- Affiliations
- University of Geneva (CH)
- University Hospital of Geneva (CH)
- Clinique Romande de Réadaptation (CH)
- University of California San Diego (US)
- Corresponding author
- Russell, Aaron P
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 2003-08-27
- Volume
- 551
- Issue
- 1-3
- Pages
- 104-106
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W2042613416
- Cited by
- 166
- References
- 13
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 7 · 2023: 5 · 2022: 2 · 2021: 4 · 2020: 2 · 2019: 7 · 2018: 8 · 2017: 4 · 2016: 8 · 2015: 8 · 2014: 12 · 2013: 5 · 2012: 11
- FWCI
- 6.38
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- FEBS Letters (publishedVersion)
- PubMed (publishedVersion)
- Archive ouverte UNIGE (University of Geneva) (publishedVersion, other-oa)
- Archive ouverte UNIGE (University of Geneva) (submittedVersion, cc-by)
- Funders
- National Science Foundation
- Stiftung für die Erforschung der Muskelkrankheiten
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (65431)
- Topics
- Health Sciences › Medicine › Biochemistry (medical) › Antioxidant Activity and Oxidative Stress
- Health Sciences › Medicine › Physiology (medical) › Exercise and Physiological Responses
- Health Sciences › Nursing › Nutrition and Dietetics › Muscle metabolism and nutrition
- Keywords
- lipid peroxidation, skeletal muscle, obesity, endurance training, insulin resistance, muscle lipids
- MeSH terms
- Adult, Aldehydes, Humans, Lipids, Male, Middle Aged, Obesity, Physical Endurance, Triglycerides, Lipid Peroxidation, Muscle, Skeletal
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
