The DOI matches its Crossref record.
AtHMA3, a plant P1B‐ATPase, functions as a Cd/Pb transporter in yeast
Open accessAbstract
The Arabidopsis thaliana AtHMA3 protein belongs to the P 1B‐adenosine triphosphatase (ATPase) transporter family, involved in heavy metal transport. Functional expression of AtHMA3 phenotypically complements the Cd/Pb‐hypersensitive yeast strain Δ ycf1, but not the Zn‐hypersensitive mutant Δ zrc1. AtHMA3‐complemented Δ ycf1 cells accumulate the same amount of cadmium as YCF1‐complemented Δ ycf1 cells or wild‐type cells, suggesting that AtHMA3 carries out an intracellular sequestration of Cd. A mutant of AtHMA3 altered in the P‐ATPase phosphorylation domain did not complement Δ ycf1, suggesting that metal transport rather than chelation is involved. The fusion protein AtHMA3::green fluorescent protein (GFP) is localized at the vacuole, consistent with a role in the influx of cadmium into the vacuolar compartment. In A. thaliana, the mRNA of AtHMA3 was detected mainly in roots, old rosette leaves and cauline leaves. The expression levels were not affected by cadmium or zinc treatments.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Krämer, U., Talke, I. N., & Hanikenne, M. (2007) · FEBS Letters · doi:10.1016/j.febslet.2007.04.010 · Cited by 583
van de Mortel, J. E., Almar Villanueva, L., Schat, H., Kwekkeboom, J., Coughlan, S., Moerland, P. D., Ver Loren van Themaat, E., Koornneef, M., & Aarts, M. G. M. (2006) · Plant Physiology · doi:10.1104/pp.106.082073 · Cited by 547
Heavy metals and soil microbes
Abdu, N., Abdullahi, A. A., & Abdulkadir, A. (2017) · Environmental Chemistry Letters · doi:10.1007/s10311-016-0587-x · Cited by 478
Mendoza-Cózatl, D. G., Jobe, T. O., Hauser, F., & Schroeder, J. I. (2011) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2011.07.004 · Cited by 435
P1B-ATPases – an ancient family of transition metal pumps with diverse functions in plants
Williams, L. E., & Mills, R. F. (2005) · Trends in Plant Science · doi:10.1016/j.tplants.2005.08.008 · Cited by 432
Metadata
- Authors
- Gravot, A., Lieutaud, A., Verret, F., Auroy, P., Vavasseur, A., & Richaud, P.
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 2004-03-05
- Volume
- 561
- Issue
- 1-3
- Pages
- 22-28
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W2088300489
- Cited by
- 200
- References
- 0
- FWCI
- 11.05
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: AtHMA3, a plant P1B‐ATPase, functions as a Cd/Pb transporter in yeast. https://app.cochat.ai/papers/10.1016/s0014-5793(04)00072-9
- The paper
- Gravot, A., Lieutaud, A., Verret, F., Auroy, P., Vavasseur, A., & Richaud, P. (2004). AtHMA3, a plant P1B‐ATPase, functions as a Cd/Pb transporter in yeast. FEBS Letters. https://doi.org/10.1016/s0014-5793(04)00072-9
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
