Transition metal transport

Krämer, Ute; Talke, Ina N.; Hanikenne, Marc

doi:10.1016/j.febslet.2007.04.010

Cited by 583Plant Micronutrient Interactions and EffectsPlant Molecular Biology ResearchPlant nutrient uptake and metabolism

Transition metal transport

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Krämer, Ute, Talke, Ina N., Hanikenne, Marc·2007·FEBS Letters

DOI 10.1016/j.febslet.2007.04.010

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Abstract

Transition metal transporters are of central importance in the plant metal homeostasis network which maintains internal metal concentrations within physiological limits. An overview is given of the functions of known transition metal transporters in the context of the unique chemical properties of their substrates. The modifications of the metal homeostasis network associated with the adaptation to an extreme metalliferous environment are illustrated in two Brassicaceae metal hyperaccumulator model plants based on cross-species transcriptomics studies. In a comparison between higher plants and unicellular algae, hypotheses are generated for evolutionary changes in metal transporter complements associated with the transition to multicellularity.

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The expression of transporter genes very often varies concerning metal ion supply, tissue, organ, and populations of hyperaccumulators.
“It is pertinent to mention that the expression of transporter genes very often varies concerning metal ion supply, tissue, organ, and populations of hyperaccumulators (Krämer et al., 2007; Verbruggen et al., 2009b; Küpper and Kochian, 2010; Visioli et al., 2014).”
From Plant hyperaccumulators: a state-of-the-art review on mechanism of heavy metal transport and sequestration (2025) · cites this paper as Krämer et al., 2007
Section 4.1 (p. 8) reports that ZIP transporter-gene expression in hyperaccumulators changes with zinc supply and differs between roots and shoots. Section 4.2 (p. 9) also describes tissue-specific expression across three accessions. The paper notes variation in metal accumulation and tolerance between populations (section 4, p. 7), but does not establish that transporter-gene expression varies between those populations. (LLM, conf=0.85)
Experimental — accuracy not yet measured
Metal ion transport into vacuoles occurs through CDF (cation diffusion facilitator), MTP (metal tolerance protein), and P1B type ATPase HMA3.
“Moreover, metal ion transport into vacuoles occurs through CDF (cation diffusion facilitator), MTP (metal tolerance protein), and P1B type ATPase HMA3 (Krämer et al., 2007; Verbruggen et al., 2009b; Andresen et al., 2018).”
From Plant hyperaccumulators: a state-of-the-art review on mechanism of heavy metal transport and sequestration (2025) · cites this paper as Krämer et al., 2007
Section 4.2 (p. 9) identifies plant CDF transporters as MTPs, and section 5.2 (p. 15) says MTP1 and MTP3 store zinc in vacuoles. The paper identifies HMA3 as a P1B-type ATPase (section 4.3, p. 10), but does not establish that HMA3 transports metals into vacuoles; section 3 (p. 6) instead reports HMA3 among ATPases exporting metals across the plasma membrane. (LLM, conf=0.88)
Experimental — accuracy not yet measured
A great deal of metal ion transport has been explored through studies on ZIP transporters, as they are involved mainly in the uptake of metal ions.
“A great deal of metal ion transport has been explored through studies on ZIP transporters, as they are involved mainly in the uptake of metal ions (Krämer et al., 2007; Andresen et al., 2018).”
From Plant hyperaccumulators: a state-of-the-art review on mechanism of heavy metal transport and sequestration (2025) · cites this paper as Krämer et al., 2007

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Biofortification of crops with seven mineral elements often lacking in human diets – iron, zinc, copper, calcium, magnesium, selenium and iodine
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Comprehensive Mechanisms of Heavy Metal Toxicity in Plants, Detoxification, and Remediation
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OsZIP1 functions as a metal efflux transporter limiting excess zinc, copper and cadmium accumulation in rice
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Role of phosphate fertilizers in heavy metal uptake and detoxification of toxic metals
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Phytoremediation of Cadmium: Physiological, Biochemical, and Molecular Mechanisms
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Heavy Metal Stress and Crop Productivity
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Rice P1B-Type Heavy-Metal ATPase, OsHMA9, Is a Metal Efflux Protein
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Microbial Biosorption of Metals
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Authors: Krämer, U., Talke, I. N., & Hanikenne, M.
Affiliations: Max Planck Institute of Molecular Plant Physiology (DE)
University of Liège (BE)
Corresponding author: Krämer, Ute
ORCID: Krämer, Ute
Talke, Ina N.
Hanikenne, Marc
Venue: FEBS Letters
Publisher: Wiley
Published: 2007-04-17
Volume: 581
Issue: 12
Pages: 2263-2272
ISSN: 0014-5793 (ISSN-L)
1873-3468
DOI: 10.1016/j.febslet.2007.04.010
OpenAlex: W2054518237
Cited by: 583
References: 79
Citations by year: 2026: 20 · 2025: 21 · 2024: 14 · 2023: 20 · 2022: 21 · 2021: 51 · 2020: 45 · 2019: 43 · 2018: 30 · 2017: 32 · 2016: 37 · 2015: 35 · 2014: 37 · 2013: 30 · 2012: 36
FWCI: 2.12
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: FEBS Letters (publishedVersion)
PubMed (publishedVersion)
ORBi (University of Liège) (submittedVersion)
Funders: European Commission (FOOD‐CT‐2006‐016253)
Deutsche Forschungsgemeinschaft
Fonds De La Recherche Scientifique - FNRS
Topics: Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Micronutrient Interactions and Effects
Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Molecular Biology Research
Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant nutrient uptake and metabolism
Keywords: plant metal homeostasis, metal hyperaccumulation, Brassicaceae, metalliferous soils, cross-species transcriptomics, multicellularity, algae
MeSH terms: Biological Transport, Active, Cell Membrane, Chelating Agents, Biological Evolution, Multigene Family, Homeostasis, Iron, Models, Biological, Plant Proteins, Plants, Genes, Plant, Protein Structure, Tertiary, Chloroplast Proton-Translocating ATPases, Membrane Transport Proteins, Cation Transport Proteins, Transition Elements

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