The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.
The window of embryo transfer and the efficiency of human conception in vitro
Open accessAbstract
Women with ovarian failure transferred with donated oocytes provide a unique in vivo model for the elucidation of the window of implantation and efficiency of reproduction in the human. Throughout 52 ovum donation cycles, the temporal window of endometrial receptivity was tested by replacing 2- to 12-cell embryos between days 16 and 24 of hormonally and histologically defined cycles. Of 37 transfers within days 17 to 19, 15 (40.5%) conceptions occurred. Twelve (32.4%) have reached viability. Of 11 patients transferred on days greater than or equal to 20, none conceived. Likewise, no pregnancies were achieved with 4 transfers on cycle day 16. Analysis of multiple embryo transfers within the suggested window of endometrial receptivity (days 17 to 19) revealed 14 of 24 (58.3%) to be conception cycles. considering only transfers with two or more embryos, at least one of which is of high quality (grades 1 to 2), yielded a 63.2% pregnancy rate. The results indicate a very high efficiency for in vitro fecundity provided optimal conditions are attained. The concepts leading to success in the ovum donation model should set the course for continued research toward improving results in other forms of assisted reproduction.
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Cites
PATHOGENESIS OF LIPOID NEPHROSIS: A DISORDER OF T-CELL FUNCTION
Shalhoub, R. (1974) · The Lancet · doi:10.1016/s0140-6736(74)91880-7 · Cited by 1,192
Early embryonic mortality in women
Edmonds, D. K., Lindsay, K. S., Miller, J. F., Williamson, E., & Wood, P. J. (1982) · Fertility and Sterility · doi:10.1016/s0015-0282(16)46579-9 · Cited by 512
Miller, J. F., Williamson, E., Glue, J., Gordon, Y. B., Grudzinskas, J. G., & Sykes, A. (1980) · The Lancet · doi:10.1016/s0140-6736(80)91991-1 · Cited by 495
A Long-term follow-up study of women using different methods of contraception— an interim report
Vessey, M., Doll, S. R., Peto, R., Johnson, B., & Wiggins, P. (1976) · Journal of Biosocial Science · doi:10.1017/s0021932000010890 · Cited by 401
Oocyte Assessment and Biological Performance
VEECK, L. L. (1988) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1988.tb22263.x · Cited by 336
Self-citationArtificially Induced Endometrial Cycles and Establishment of Pregnancies in the Absence of Ovaries
Navot, D., Laufer, N., Kopolovic, J., Rabinowitz, R., Birkenfeld, A., Lewin, A., Granat, M., Margalioth, E. J., & Schenker, J. G. (1986) · New England Journal of Medicine · doi:10.1056/nejm198603273141302 · Cited by 295
Self-citationWHERE HAVE ALL THE CONCEPTIONS GONE?
ROBERTS, C. (1975) · The Lancet · doi:10.1016/s0140-6736(75)92837-8 · Cited by 263
Donor eggs: their application in modern reproductive technologies
Rosenwaks, Z. (1987) · Fertility and Sterility · doi:10.1016/s0015-0282(16)59220-6 · Cited by 217
Self-citationGarcia, J. E., Acosta, A. A., Hsiu, J.-G., & Jones, H. W. (1984) · Fertility and Sterility · doi:10.1016/s0015-0282(16)47536-9 · Cited by 206
Evidence for an adverse effect of elevated serum estradiol concentrations on embryo implantation
Forman, R., Belaisch-Allart, J., Fries, N., Hazout, A., Testart, J., & Frydman, R. (1988) · Fertility and Sterility · doi:10.1016/s0015-0282(16)59661-7 · Cited by 191
Cited by
Frozen embryo transfer: a review on the optimal endometrial preparation and timing
Mackens, S., Santos-Ribeiro, S., van de Vijver, A., Racca, A., Van Landuyt, L., Tournaye, H., & Blockeel, C. (2017) · Human Reproduction · doi:10.1093/humrep/dex285 · Cited by 361
The endometrium in stimulated cycles for IVF
Bourgain, C., & Devroey, P. (2003) · Human Reproduction Update · doi:10.1093/humupd/dmg045 · Cited by 339
van de Vijver, A., Polyzos, N. P., Van Landuyt, L., Mackens, S., Stoop, D., Camus, M., De Vos, M., Tournaye, H., & Blockeel, C. (2016) · Human Reproduction · doi:10.1093/humrep/dew045 · Cited by 66
Juárez-Barber, E., Cozzolino, M., Corachán, A., Alecsandru, D., Pellicer, N., Pellicer, A., & Ferrero, H. (2023) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2022.09.007 · Cited by 16
Metadata
- Authors
- Navot, D., Scott, R. T., Droesch, K., Veeck, L. L., Liu, H.-C., & Rosenwaks, Z.
- Venue
- Fertility and Sterility
- Publisher
- Elsevier BV
- Published
- 1991-01
- Volume
- 55
- Issue
- 1
- Pages
- 114-118
- ISSN
- 0015-0282 (ISSN-L)
- OpenAlex
- W2280592538
- Cited by
- 299
- References
- 21
- FWCI
- 16.45
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- CoChat. (2026). Citation check: The window of embryo transfer and the efficiency of human conception in vitro. https://app.cochat.ai/papers/10.1016/s0015-0282(16)54069-2
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- Navot, D., Scott, R. T., Droesch, K., Veeck, L. L., Liu, H.-C., & Rosenwaks, Z. (1991). The window of embryo transfer and the efficiency of human conception in vitro. Fertility and Sterility. https://doi.org/10.1016/s0015-0282(16)54069-2
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
