Su1966 An Assessment of Cognitive Function in Irritable Bowel Syndrome (IBS): Are Deficits in Visuo-Spatial Memory Stress-Related and Mediated by Tryptophan Metabolism Along the Kynurenine Pathway?
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Specific cognitive changes in IBS relate to hippocampal-mediated visuospatial memory deficits that are linked to indices of HPA axis function.
“Cognitive alterations may be present in individuals with IBS, and evidence is emerging that specific changes relate to hippocampal-mediated visuospatial memory deficits, which are linked to indices of HPA axis function (20, 496–498).”
From Signalling cognition: The gut microbiota and hypothalamic-pituitary-adrenal axis (2023) · cites this paper as [496]
Cognitive alterations may be present in individuals with IBS.
“Cognitive alterations may be present in individuals with IBS, and evidence is emerging that specific changes relate to hippocampal-mediated visuospatial memory deficits, which are linked to indices of HPA axis function (20, 496–498).”
From Signalling cognition: The gut microbiota and hypothalamic-pituitary-adrenal axis (2023) · cites this paper as [496]
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Signalling cognition: The gut microbiota and hypothalamic-pituitary-adrenal axis
Rusch, J. A., Layden, B. T., & Dugas, L. R. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1130689 · Cited by 415 · see citing works
- Authors
- Kennedy, P. J., Clarke, G., O'Neill, A., Groeger, J. A., Quigley, E. M., Shanahan, F., Cryan, J. F., & Dinan, T. G.
- ORCID
- Venue
- Gastroenterology
- Publisher
- Elsevier BV
- Published
- 2012-05
- Volume
- 142
- Issue
- 5
- Pages
- S-548
- ISSN
- 0016-5085 (ISSN-L)
- OpenAlex
- W2180770317
- Cited by
- 1
- References
- 0
- Citations by year
- 2023: 1
- Type
- conference abstract
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Gastroenterology (publishedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Life Sciences › Neuroscience › Biological Psychiatry › Tryptophan and brain disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Inflammatory Bowel Disease
- Keywords
- irritable bowel syndrome, visuospatial memory, cognitive function, tryptophan metabolism, kynurenine pathway, stress, corticotropin-releasing factor, colorectal distension, gut-brain axis, ACTH, cortisol, brain activation
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