The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
Recognition sequence of the dam methylase of Escherichia coli K12 and mode of cleavage of Dpn I endonuclease.
Open accessAbstract
The recognition sequence for the dam methylase of Escherichia coli K12 has been determined directly by use of in vivo methylated ColE1 DNA or DNA methylated in vitro with purified enzyme. The methylase recognizes the symmetric tetranucleotide d(pG-A-T-C) and introduces two methyl groups per site in duplex DNA with the product of methylation being 6-methylaminopurine. This work has also demonstrated that Dpn I restriction endonuclease cleaves on the 3' side of the modified adenine within the methylated sequence to yield DNA fragments possessing fully base-paired termini. All sequences in ColE1 DNA methylated by the dam enzyme are subject to double strand cleavage by Dpn I endonuclease. Therefore, this restriction enzyme can be employed for mapping the location of sequences possessing the dam modification.
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PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT
Lowry, O., Rosebrough, N., Farr, A. L., & Randall, R. (1951) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)52451-6 · Cited by 317,331
A procedure for the isolation of deoxyribonucleic acid from micro-organisms
Marmur, J. (1961) · Journal of Molecular Biology · doi:10.1016/s0022-2836(61)80047-8 · Cited by 11,545
A simplified method for cyanogen bromide activation of agarose for affinity chromatography
March, S. C., Parikh, I., & Cuatrecasas, P. (1974) · Analytical Biochemistry · doi:10.1016/0003-2697(74)90139-0 · Cited by 1,935
McDonell, M. W., Simon, M. N., & Studier, F. W. (1977) · Journal of Molecular Biology · doi:10.1016/s0022-2836(77)80102-2 · Cited by 1,585
Polyacrylamide Gel Electrophoresis of Viral Proteins
Maizel, J. V. (1971) · Methods in Virology · doi:10.1016/b978-0-12-470205-9.50011-3 · Cited by 1,461
Nature of Col E 1 Plasmid Replication in Escherichia coli in the Presence of Chloramphenicol
Clewell, D. B. (1972) · Journal of Bacteriology · doi:10.1128/jb.110.2.667-676.1972 · Cited by 1,184
Burgess, R. R., & Jendrisak, J. J. (1975) · Biochemistry · doi:10.1021/bi00692a011 · Cited by 1,144
Enzymatic Synthesis of Deoxyribonucleic Acid
Josse, J., Kaiser, A. D., & Kornberg, A. (1961) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)64321-2 · Cited by 753
Phosphorylation of nucleic acid by an enzyme from T4 bacteriophage-infected Escherichia coli.
Richardson, C. C. (1965) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.54.1.158 · Cited by 607
[40] Thin-layer separation methods for nucleic acid derivatives
Randerath, K., & Randerath, E. (1967) · Methods in Enzymology · doi:10.1016/s0076-6879(67)12049-1 · Cited by 502
Cited by
Nomenclature for incompletely specified bases in nucleic acid sequences: rcommendations 1984
Cornish-Bowden, A. (1985) · Nucleic Acids Research · doi:10.1093/nar/13.9.3021 · Cited by 548
Bacterial retrons encode phage-defending tripartite toxin–antitoxin systems
Bobonis, J., Mitosch, K., Mateus, A., Karcher, N., Kritikos, G., Selkrig, J., Zietek, M., Monzon, V., Pfalz, B., Garcia-Santamarina, S., et al. (2022) · Nature · doi:10.1038/s41586-022-05091-4 · Cited by 165
Gelfand, M. S., & Koonin, E. V. (1997) · Nucleic Acids Research · doi:10.1093/nar/25.12.2430 · Cited by 134
Krašovec, R., Belavkin, R. V., Aston, J. A. D., Channon, A., Aston, E., Rash, B. M., Kadirvel, M., Forbes, S., & Knight, C. G. (2014) · Nature Communications · doi:10.1038/ncomms4742 · Cited by 85
Metadata
- Authors
- Geier, G. E., & Modrich, P.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1979-02
- Volume
- 254
- Issue
- 4
- Pages
- 1408-1413
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1589224106
- Cited by
- 332
- References
- 27
- FWCI
- 5.96
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Geier, G. E., & Modrich, P. (1979). Recognition sequence of the dam methylase of Escherichia coli K12 and mode of cleavage of Dpn I endonuclease. Journal of Biological Chemistry. https://doi.org/10.1016/s0021-9258(17)34217-5
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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