The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.
Different accessibilities in chromatin to histone acetylase.
Open accessAbstract
The addition of millimolar concentrations of n-butyr- ate to tissue culture media has been shown to cause a dramatic buildup of the acetylated l -aminolysine forms of cellular histones, without causing cell death We find that n-butyrate acts by strongly inhibiting histone deacetylation, without any apparent effect on the acetylation reaction, per se. In a rat hepatoma cell line (HTC cells), the presence of high concentrations of n-butyrate causes the in viva half-life of the normally labile histone acetyl groups to be extended over 150-fold to more than 24 h. All his- tones naturally acetylated in uiuo (H2a, H2b, H3, and H4) are affected, and deacetylation is inhibited regard-less of the number of acetyl groups present on any particular histone. n-Butyrate vitro of
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Cites
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Dalile, B., Van Oudenhove, L., Vervliet, B., & Verbeke, K. (2019) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-019-0157-3 · Cited by 3,357
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Tan, J., McKenzie, C., Potamitis, M., Thorburn, A. N., Mackay, C. R., & Macia, L. (2014) · Advances in immunology · doi:10.1016/b978-0-12-800100-4.00003-9 · Cited by 2,425
Inhibition of Histone Deacetylase Activity by Butyrate
Davie, J. R. (2003) · The Journal of Nutrition · doi:10.1093/jn/133.7.2485s · Cited by 1,515
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Metadata
- Authors
- Cousens, L. S., Gallwitz, D., & Alberts, B. M.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1979-03
- Volume
- 254
- Issue
- 5
- Pages
- 1716-1723
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W138633729
- Cited by
- 340
- References
- 30
- FWCI
- 11.41
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Cousens, L. S., Gallwitz, D., & Alberts, B. M. (1979). Different accessibilities in chromatin to histone acetylase. Journal of Biological Chemistry. https://doi.org/10.1016/s0021-9258(17)37831-6
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
