The DOI matches its Crossref record.
Homeobox gene expression in the intestinal epithelium of adult mice.
Open accessAbstract
Using a polymerase chain reaction-based strategy, we have detected the expression of nine different homeobox genes in adult mouse intestine. Included among these are the recently described intestine-specific Cdx-1 gene and a new, related gene, Cdx-2. Southern blot experiments show that Cdx-2 is present in a single copy in the mouse genome. Of several adult mouse tissues assayed, intestine was the only one that contained detectable levels of Cdx-2 mRNA. Expression of all nine homeobox genes in different regions of the intestine was quantitated by RNase protection analysis, which revealed a unique expression profile for each gene. These observations suggest that homeobox gene expression may play an important role in cellular differentiation in the adult intestine.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
GFAP promoter elements required for region‐specific and astrocyte‐specific expression
Lee, Y., Messing, A., Su, M., & Brenner, M. (2008) · Glia · doi:10.1002/glia.20622 · Cited by 424
Beck, F., Erler, T., Russell, A., & James, R. (1995) · Developmental Dynamics · doi:10.1002/aja.1002040302 · Cited by 406
Self-citationJames, R., Erler, T., & Kazenwadel, J. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)36596-1 · Cited by 269
Self-citationHOXA5 Counteracts Stem Cell Traits by Inhibiting Wnt Signaling in Colorectal Cancer
Ordóñez-Morán, P., Dafflon, C., Imajo, M., Nishida, E., & Huelsken, J. (2015) · Cancer Cell · doi:10.1016/j.ccell.2015.11.001 · Cited by 209
Intestinal mucosal atrophy and adaptation
Shaw, D. (2012) · World Journal of Gastroenterology · doi:10.3748/wjg.v18.i44.6357 · Cited by 133
Metadata
- Authors
- James, R., & Kazenwadel, J.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1991-02
- Volume
- 266
- Issue
- 5
- Pages
- 3246-3251
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1500070160
- Cited by
- 208
- References
- 0
- FWCI
- 4.34
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Homeobox gene expression in the intestinal epithelium of adult mice. https://app.cochat.ai/papers/10.1016/s0021-9258(18)49981-4
- The paper
- James, R., & Kazenwadel, J. (1991). Homeobox gene expression in the intestinal epithelium of adult mice. Journal of Biological Chemistry. https://doi.org/10.1016/s0021-9258(18)49981-4
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.