The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.
On the Regulation of Guanosine Tetraphosphate Levels in Stringent and Relaxed Strains of Escherichia coli
Open accessAbstract
We have examined the intracellular levels of the guanosine tetraphosphate, guanosine 5'-diphosphate 2'- or 3'-diphosphate (ppGpp), in an isogenic pair of stringent and relaxed strains of Escherichia coli. As previously observed, relaxed strains do not accumulate ppGpp during amino acid deprivation, while stringent strains do. However, under all other culture conditions examined, relaxed and stringent cells regulate their ppGpp levels similarly. During carbon deprivation or step-down transitions both strains accumulate ppGpp. Neither strain accumulates appreciable amounts during phosphate deprivation or after treatment with colicin E1. The basal levels of ppGpp observed in both stringent and relaxed strains during balanced growth are, in most cases, the same, and vary inversely with the growth rate and RNA content of the cells.
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Cites
Burton, K. (1956) · Biochemical Journal · doi:10.1042/bj0620315 · Cited by 14,090
The Role of Polyamines in the Neutralization of Bacteriophage Deoxyribonucleic Acid
Ames, B. N., & Dubin, D. T. (1960) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)67936-6 · Cited by 2,579
PHOSPHORUS COMPOUNDS IN ANIMAL TISSUES
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A GENETIC LOCUS FOR THE REGULATION OF RIBONUCLEIC ACID SYNTHESIS
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The Control of Ribonucleic Acid Synthesis in Escherichia coli
Cashel, M. (1969) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)93106-6 · Cited by 449
Self-citationThe Control of Ribonucleic Acid Synthesis in Escherichia coli
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Self-citationStudies on the role of ribonucleic acid in the growth of bacteria
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The Control of Ribonucleic Acid Synthesis during Amino Acid Deprivation in Escherichia coli
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Self-citationMessenger RNA synthesis during amino acid starvation in Escherichia coli
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Cited by
TUOMANEN, E., COZENS, R., TOSCH, W., ZAK, O., & TOMASZ, A. (1986) · Microbiology · doi:10.1099/00221287-132-5-1297 · Cited by 477
Atkinson, G. C., Tenson, T., & Hauryliuk, V. (2011) · PLoS ONE · doi:10.1371/journal.pone.0023479 · Cited by 447
Control of rRNA transcription in Escherichia coli
Condon, C., Squires, C., & Squires, C. L. (1995) · Microbiological Reviews · doi:10.1128/mr.59.4.623-645.1995 · Cited by 349
MSI and MSII made on Ribosome in Idling Step of Protein Synthesis
HASELTINE, W. A., BLOCK, R., GILBERT, W., & WEBER, K. (1972) · Nature · doi:10.1038/238381a0 · Cited by 317
Regulation of the Protein-Synthesizing Machinery—Ribosomes, tRNA, Factors, and So On
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Metadata
- Authors
- Lazzarini, R. A., Cashel, M., & Gallant, J.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1971-07
- Volume
- 246
- Issue
- 14
- Pages
- 4381-4385
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1890358491
- Cited by
- 290
- References
- 15
- FWCI
- 22.86
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Lazzarini, R. A., Cashel, M., & Gallant, J. (1971). On the Regulation of Guanosine Tetraphosphate Levels in Stringent and Relaxed Strains of Escherichia coli. Journal of Biological Chemistry. https://doi.org/10.1016/s0021-9258(18)62023-x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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