The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
STUDIES ON THE MECHANISM OF ACTION OF THE ADRENOCORTICOTROPIC HORMONE
Open accessAbstract
It has been demonstrated that adrenocorticotropic hormone (ACTH) stimulates isolated, perfused adrenal glands (1) and adrenocortical tissue slices (2, 3) to release increased quantities of corticosteroid hormones. These findings are in accord with the well established fact that ACTH in tivo causes the adrenal cortex to secrete increased quantities of the adrenal steroid hormones. The present work was performed in an attempt to learn more about the mechanism by which ACTH effects this stimulation of the adrenal cortex. The first group of experiments indicated that ACTH acts primarily by increasing the rate of corticosteroid synthesis rather than by primarily causing release of the steroid hormones. Further investigation of the mechanism of action of ACTH revealed that the adrenal stimulation is accompanied by an increase of phosphorylase activity in the tissue. Data will be presented showing the relationship between phosphorylase activity and steroidogenesis.
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Citations
Cites
THE RELATIONSHIP OF EPINEPHRINE AND GLUCAGON TO LIVER PHOSPHORYLASE
Rall, T. W., Sutherland, E. W., & Berthet, J. (1957) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)65045-8 · Cited by 493
Stone, D., & Hechter, O. (1954) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(54)90501-9 · Cited by 445
THE RELATIONSHIP OF EPINEPHRINE AND GLUCAGON TO LIVER PHOSPHORYLASE
Sutherland, E. W., & Wosilait, W. D. (1956) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)65909-5 · Cited by 370
IDENTIFICATION OF CORTICOSTEROIDS OF BEEF ADRENAL EXTRACT BY PAPER CHROMATOGRAPHY
Zaffaroni, A., & Burton, R. B. (1951) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)50931-5 · Cited by 286
EFFECT OF HYPERGLYCEMIC-GLYCOGENOLYTIC FACTOR AND EPINEPHRINE ON LIVER PHOSPHORYLASE
Sutherland, E. W., & Cori, C. F. (1951) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)77725-4 · Cited by 247
THE RELATIONSHIP OF EPINEPHRINE AND GLUCAGON TO LIVER PHOSPHORYLASE
Wosilait, W. D., & Sutherland, E. W. (1956) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)65910-1 · Cited by 229
Sweat, M. L., & Lipscomb, M. D. (1955) · Journal of the American Chemical Society · doi:10.1021/ja01624a080 · Cited by 92
IN VITRO BIOASSAY OF CORTICOTROPHIN
Saffran, M., & BAYLISS, M. J. (1953) · Endocrinology · doi:10.1210/endo-52-2-140 · Cited by 73
Cited by
Garren, L. D., Ney, R. L., & Davis, W. W. (1965) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.53.6.1443 · Cited by 386
Halkerston, I. D. K., Eichhorn, J., & Hechter, O. (1961) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)64370-4 · Cited by 192
Changes of plasma and adrenal corticosterone levels in the rat after repeated stimuli
Stockham, M. A. (1964) · The Journal of Physiology · doi:10.1113/jphysiol.1964.sp007448 · Cited by 28
Some aspects of the glucagon problem
Berthet, J. (1959) · The American Journal of Medicine · doi:10.1016/0002-9343(59)90229-3 · Cited by 27
Metadata
- Authors
- Haynes, R. C., & Berthet, L.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1957-03
- Volume
- 225
- Issue
- 1
- Pages
- 115-124
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W166247894
- Cited by
- 332
- References
- 8
- FWCI
- 17.30
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Haynes, R. C., & Berthet, L. (1957). STUDIES ON THE MECHANISM OF ACTION OF THE ADRENOCORTICOTROPIC HORMONE. Journal of Biological Chemistry. https://doi.org/10.1016/s0021-9258(18)64914-2
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
