The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.
Presence of three distinct molecular species of Gi protein alpha subunit. Structure of rat cDNAs and human genomic DNAs.
Open accessAbstract
We have cloned a new species of rat Gi alpha (Gi3 alpha) cDNA and genomic DNAs for three distinct human Gi alpha proteins (Gi1 alpha, Gi2 alpha, and Gi3 alpha). Gi3 alpha cDNA codes for a protein of 354 amino acids (Mr 40,522) whose sequence is closely related but distinct from that of the previously isolated rat Gi alpha (Gi2 alpha). By screening the human genomic libraries with the two rat Gi alpha cDNAs as probes, clones encoding human Gi1 alpha, Gi2 alpha, and Gi3 alpha were isolated. The human Gi2 alpha and Gi3 alpha genes are composed of eight coding exons and seven introns and possess a completely identical exon-intron organization. Southern blot analysis indicates that a single copy of each Gi alpha gene is present per haploid human genome.
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Cited by
Gromada, J., Høy, M., Buschard, K., Salehi, A., & Rorsman, P. (2001) · The Journal of Physiology · doi:10.1111/j.1469-7793.2001.00519.x · Cited by 120
Metadata
- Authors
- Itoh, H., Toyama, R., Kozasa, T., Tsukamoto, T., Matsuoka, M., & Kaziro, Y.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1988-05
- Volume
- 263
- Issue
- 14
- Pages
- 6656-6664
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1534821377
- Cited by
- 271
- References
- 38
- FWCI
- 11.94
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Itoh, H., Toyama, R., Kozasa, T., Tsukamoto, T., Matsuoka, M., & Kaziro, Y. (1988). Presence of three distinct molecular species of Gi protein alpha subunit. Structure of rat cDNAs and human genomic DNAs. Journal of Biological Chemistry. https://doi.org/10.1016/s0021-9258(18)68692-2
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
