The metabolism of progesterone by liver tissue in vitro
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Progestogens are primarily metabolized by the liver largely to form pregnanediols and pregnanolones.
“Progestogens are primarily metabolized by the liver largely to form pregnanediols and pregnanolones [336,337].”
From Human steroid biosynthesis, metabolism and excretion are differentially reflected by serum and urine steroid metabolomes: a comprehensive review (2019) · cites this paper as [336]
Cites
Callow, N. H., Callow, R. K., & EMMENS, C. W. (1938) · Biochemical Journal · doi:10.1042/bj0321312 · Cited by 454 · see citing works
Venning, E. H., & Browne, J. S. L. (1937) · Endocrinology · doi:10.1210/endo-21-6-711 · Cited by 152 · see citing works
A STUDY OF THE METABOLISM OF CRYSTALLINE PROGESTERONE
Venning, E. H., & Browne, J. S. L. (1940) · Endocrinology · doi:10.1210/endo-27-5-707 · Cited by 55 · see citing works
(1948) · Journal of the Franklin Institute · doi:10.1016/0016-0032(48)90376-7 · Cited by 48 · see citing works
METABOLISM OF STEROIDS BY TISSUES
Samuels, L. T., McCaulay, C., & Sellers, D. M. (1947) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)30908-0 · Cited by 46 · see citing works
Self-citationRecovery of Pregnandiol in Urine of Men Treated with Progesterone.
Buxton, C. L., & Westphal, U. (1939) · Experimental Biology and Medicine · doi:10.3181/00379727-41-10648 · Cited by 40 · see citing works
Clinical and Experimental Investigations on the Genital Functions and Their Hormonal Regulation.
(1941) · Annals of Internal Medicine · doi:10.7326/0003-4819-15-3-621 · Cited by 36 · see citing works
METABOLISM OF TESTOSTERONE AND 17-METHYL-TESTOSTERONE BY LIVER TISSUE
Levedahl, B. H., & Samuels, L. T. (1950) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)56278-5 · Cited by 31 · see citing works
Self-citationMETABOLISM OF STEROIDS BY TISSUES
Samuels, L. T. (1947) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)30907-9 · Cited by 26 · see citing works
Self-citationTHE SITE OF METABOLISM OF PROGESTERONE IN THE RABBIT
Kochakian, C. D., Haskins, A. L., & Bruce, R. A. (1944) · American Journal of Physiology-Legacy Content · doi:10.1152/ajplegacy.1944.142.3.326 · Cited by 24 · see citing works
STUDIES ON THE ROLE OF THE LIVER IN THE METABOLISM OF PROGESTERONE11
Masson, G. M. C., & Hoffman, M. M. (1945) · Endocrinology · doi:10.1210/endo-37-2-111 · Cited by 22 · see citing works
ON THE RÔLE OF THE LIVER IN THE DETOXIFICATION OF STEROID HORMONES AND ARTIFICIAL ESTROGENS
Selye, H. (1941) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)03447-0 · Cited by 21 · see citing works
ISOLATION OF PREGNANEDIOL FROM HUMAN BILE AFTER ORAL ADMINISTRATION OF PROGESTERONE
Rogers, J., & McLELLAN, F. (1951) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-11-3-246 · Cited by 17 · see citing works
A STUDY ON INACTIVATION OF OVARIAN HORMONES BY THE LIVER
(1944) · Endocrinology · doi:10.1210/endo-35-1-70 · Cited by 13 · see citing works
HAMBLEN, E. C., Cuyler, W. K., & Hirst, D. V. (1940) · Endocrinology · doi:10.1210/endo-27-2-172 · Cited by 12 · see citing works
The metabolism of progesterone in the hysterectomized woman
JONES, G. E. S., & TeLinde, R. W. (1941) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(41)90664-6 · Cited by 11 · see citing works
A STUDY OF PROGESTERONE INACTIVATION BY THE LIVER AFTER INTRAPORTAL ADMINISTRATION
Engel, P. C. (1946) · Endocrinology · doi:10.1210/endo-38-3-215 · Cited by 10 · see citing works
STUDIES CONCERNING THE ABSORPTION AND DETOXIFICATION OF ANESTHETIC STEROIDS
Selye, H., & STONE, H. (1944) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)09111-6 · Cited by 6 · see citing works
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Schiffer, L., Barnard, L., Baranowski, E. S., Gilligan, L. C., Taylor, A. E., Arlt, W., Shackleton, C. H. L., & Storbeck, K.-H. (2019) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2019.105439 · Cited by 450 · see citing works
“Progestogens are primarily metabolized by the liver largely to form pregnanediols and pregnanolones [336,337].”
- Authors
- Wiswell, J. G., & Samuels, L. T.
- Affiliations
- University of Utah (US)
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1953-03
- Volume
- 201
- Issue
- 1
- Pages
- 155-160
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W2336214067
- Cited by
- 21
- References
- 18
- Citations by year
- 2024: 1 · 2019: 1 · 2013: 1
- FWCI
- 3.62
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Biological Chemistry (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Steroid Chemistry and Biochemistry
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Pharmacogenetics and Drug Metabolism
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
- Keywords
- progesterone, steroid metabolism, liver, in vitro metabolism
- MeSH terms
- Humans, Liver, Progesterone, Lipid Metabolism, In Vitro Techniques
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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