The DOI matches its Crossref record, with a small difference in title or year.
THE ISOELECTRIC POINT OF INSULIN
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Many proteins lose hydrophilicity near their isoelectric point.
“Many proteins are known to lose hydrophilicity near their IEP.”
From Reversal of ApoE4-induced recycling block as a novel prevention approach for Alzheimer’s disease (2018) · cites this paper as Wintersteiner and Abramson, 1933
Reduced solubility at or near their isoelectric point is a general property of many proteins including insulin.
“reduced solubility at or near their isoelectric point is a general property of many proteins including insulin (Wintersteiner and Abramson, 1933).”
From Reversal of ApoE4-induced recycling block as a novel prevention approach for Alzheimer’s disease (2018) · cites this paper as Wintersteiner and Abramson, 1933
The propensity of many proteins to lose hydrophilicity at or near their isoelectric point makes them prone to aggregation and precipitation.
“As a mechanistic basis we propose the propensity of many proteins to lose hydrophilicity at or near their isoelectric point, which makes them prone to aggregation and precipitation, a seminal discovery that made the purification of insulin on an industrial scale possible (Wintersteiner and Abramson, 1933).”
From Reversal of ApoE4-induced recycling block as a novel prevention approach for Alzheimer’s disease (2018) · cites this paper as Wintersteiner and Abramson, 1933
Citations
Cites
No references could be resolved yet.
Research works printed but not linked: 10
- Abel, 1926, Proc. Nat. Acad. Sc., 12, 132, 10.1073/pnas.12.2.132 · DOI
- Sörensen, 1930, Compt.-rend. trav. Lab. Carlsberg, 18
- Freudenberg, 1931, Z. physiol. Chem., 202, 192, 10.1515/bchm2.1931.202.4-6.192 · DOI
- Abel, 1927, J. Pharmacol. and Exp. Therap., 31, 65, 10.1016/S0022-3565(25)00006-0 · DOI
- Rosebury, 1932, Ind. and Eng. Chem., Anal. Ed., 4, 398, 10.1021/ac50080a027 · DOI
- MacInnes, 1929, Ind. and Eng. Chem., Anal. Ed., 1, 57, 10.1021/ac50066a001 · DOI
- Abramson, 1932, J. Gen. Physiol., 15, 575, 10.1085/jgp.15.5.575 · DOI
- Tiselius, A., Dissertation, Upsala (1930).
- Abramson, 1931, Physic. Rev., 37, 1714
- Howitt, 1932, Proc. Roy. Soc. London, Series B, 112, 13, 10.1098/rspb.1932.0073 · DOI
Cited by
Sorted by citations
Reversal of ApoE4-induced recycling block as a novel prevention approach for Alzheimer’s disease
Xian, X., Pohlkamp, T., Durakoglugil, M. S., Wong, C. H., Beck, J. K., Lane-Donovan, C., Plattner, F., & Herz, J. (2018) · eLife · doi:10.7554/elife.40048 · Cited by 98
Vance, J. M., Farrer, L. A., Huang, Y., Cruchaga, C., Hyman, B. T., Pericak‐Vance, M. A., Goate, A. M., Greicius, M. D., Griswold, A. J., Haines, J. L., et al. (2024) · Annals of Neurology · doi:10.1002/ana.26864 · Cited by 52
NHE6 depletion corrects ApoE4-mediated synaptic impairments and reduces amyloid plaque load
Pohlkamp, T., Xian, X., Wong, C. H., Durakoglugil, M. S., Werthmann, G. C., Saido, T. C., Evers, B. M., White, C. L., Connor, J., Hammer, R. E., et al. (2021) · eLife · doi:10.7554/elife.72034 · Cited by 46
Metadata
- Authors
- Wintersteiner, O., & Abramson, H. A.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1933-02
- Volume
- 99
- Issue
- 3
- Pages
- 741-753
- ISSN
- 0021-9258
- Cited by
- 84
- References
- 0
- Language
- en
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
