The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
Swelling and Lysis of Rat Liver Mitochondria Induced by Ferrous Ions
Open accessAbstract
The possibility that ascorbateand reduced glutathioneinduced swelling and lysis of mitochondria (1,2) were dependent on some metal, such as iron, which was contaminating reagents, or even the nonheme iron in mitochondria led us to investigate the action of added iron. The ferrous ion was of special interest as a result of its role in several reactions catalyzed by ascorbate (3, 4). The promotion of swelling by many ions, including iron, has been reported by several workers (5-7), but the characteristic phenomena to be described here were apparently obscured by various conditions. Unlike swelling induced by many other substances uch as phosphate and thyroxine, (8, 9), swelling with ascorbate, reduced glutathione, or Fe++ is not dependent on endogenous or added substrates. There is a close correlation between lipid peroxide formation and swelling or lysis induced by Fe*, J ‘ust as has been observed with ascorbate and oxidized plus reduced glutathione (1). Whether or not such effects contribute to physiological control or pathological phenomena remains to be seen, but these studies with isolated mitochondria provide additional information about structure and permeability control in the mitochondrial membranes.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The Thiobarbituric Acid Assay of Sialic Acids
Warren, L. (1959) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)69851-5 · Cited by 6,433
The thiobarbituric acid reaction and the autoxidations of polyunsaturated fatty acid methyl esters
Dahle, L. K., Hill, E. G., & Holman, R. T. (1962) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(62)90181-9 · Cited by 839
ASCORBIC ACID IN AROMATIC HYDROXYLATION
Udenfriend, S., Clark, C. T., Axelrod, J., & Brodie, B. B. (1954) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)65598-x · Cited by 677
THE REACTION BETWEEN THIOBARBITURIC ACID AND THE OXIDATION PRODUCTS OF CERTAIN LIPIDES
Bernheim, F., Bernheim, M. L. C., & Wilbur, K. M. (1948) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)57394-4 · Cited by 662
Interaction of ascorbic acid and mitochondrial lipides
Ottolenghi, A. (1959) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(59)90414-x · Cited by 521
SINNHUBER, R. O., YU, T. C., & YU, T. C. (1958) · Journal of Food Science · doi:10.1111/j.1365-2621.1958.tb17614.x · Cited by 398
Hunter, F. E., & Ford, L. (1955) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)52312-2 · Cited by 279
Self-citationThe mechanism of the oxidation of unsaturated fatty acids catalyzed by hematin compounds
Tappel, A. L. (1953) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(53)90056-3 · Cited by 268
Some calculations on the turbidity of mitochondria and bacteria
Koch, A. L. (1961) · Biochimica et Biophysica Acta · doi:10.1016/0006-3002(61)90599-6 · Cited by 256
KOHN, H. I., & LIVERSEDGE, M. (1944) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)08738-5 · Cited by 240
Cited by
Lipid Peroxidation and Mechanisms of Toxicity
Horton, A. A., Fairhurst, S., & Bus, J. S. (1987) · CRC Critical Reviews in Toxicology · doi:10.3109/10408448709089856 · Cited by 339
Generation of oxygen radicals by minerals and its correlation to cytotoxicity.
Vallyathan, V (1994) · Environmental Health Perspectives · doi:10.1289/ehp.94102s10111 · Cited by 66
Castranova, V, Vallyathan, V, Ramsey, D. M., McLaurin, J. L., Pack, D., Leonard, S., Barger, M. W., Ma, J. Y., Dalal, N. S., & Teass, A. (1997) · Environmental Health Perspectives · doi:10.1289/ehp.97105s51319 · Cited by 31
Metadata
- Authors
- Hunter, F. E., Gebicki, J. M., Hoffsten, P. E., Weinstein, J., & Scott, A.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1963-02
- Volume
- 238
- Issue
- 2
- Pages
- 828-835
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W18546601
- Cited by
- 517
- References
- 18
- FWCI
- 31.47
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Swelling and Lysis of Rat Liver Mitochondria Induced by Ferrous Ions. https://app.cochat.ai/papers/10.1016/s0021-9258(18)81341-2
- The paper
- Hunter, F. E., Gebicki, J. M., Hoffsten, P. E., Weinstein, J., & Scott, A. (1963). Swelling and Lysis of Rat Liver Mitochondria Induced by Ferrous Ions. Journal of Biological Chemistry. https://doi.org/10.1016/s0021-9258(18)81341-2
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
