The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Identification of a putative isoform of the Na,K-ATPase β subunit
Open accessAbstract
We have isolated cDNA clones from rat brain and human liver encoding a putative isoform of the Na,K-ATPase beta subunit. The rat brain cDNA contains an open reading frame of 870 nucleotides coding for a protein of 290 amino acids with a calculated molecular weight of 33,412. The corresponding amino acid sequence shows 98% identity with its human liver counterpart. The proteins encoded by the rat and human cDNAs exhibit a high degree of primary sequence and secondary structure similarity with the rat Na,K-ATPase beta subunit. We have therefore termed the polypeptides these cDNAs encode a beta 2 subunit with the previously characterized rat cDNA encoding a beta 1 subunit. Analysis of rat tissue RNA reveals that the beta 2 subunit gene encodes a 3.4-kilobase mRNA which is expressed in a tissue specific fashion distinct from that of rat beta 1 subunit mRNA. Cell lines derived from the rat central nervous system shown to lack beta 1 subunit mRNA sequences were found to express beta 2 subunit mRNA. These results suggest that different members of the Na,K-ATPase beta subunit family may have specialized functions.
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Cites
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Cited by
Isozymes of the Na-K-ATPase: heterogeneity in structure, diversity in function
Blanco, G., & Mercer, R. W. (1998) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.1998.275.5.f633 · Cited by 1,243
Lobato-Álvarez, J. A., Roldán, M. L., López-Murillo, T. D. C., González-Ramírez, R., Bonilla-Delgado, J., & Shoshani, L. (2016) · Frontiers in Physiology · doi:10.3389/fphys.2016.00450 · Cited by 27
Metadata
- Authors
- Martin-Vasallo, P., Dackowski, W., Emanuel, J. R., & Levenson, R.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1989-03
- Volume
- 264
- Issue
- 8
- Pages
- 4613-4618
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1573051141
- Cited by
- 270
- References
- 19
- FWCI
- 10.79
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Martin-Vasallo, P., Dackowski, W., Emanuel, J. R., & Levenson, R. (1989). Identification of a putative isoform of the Na,K-ATPase β subunit. Journal of Biological Chemistry. https://doi.org/10.1016/s0021-9258(18)83787-5
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.