Cited by 53Muscle metabolism and nutritionAmino Acid Enzymes and MetabolismFood Nutrient Composition and Product Development

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THE CREATINE CONTENT OF MUSCLE UNDER NORMAL CONDITIONS. ITS RELATION TO THE URINARY CREATININE

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Myers, Victor C., Fine, Morris S.·1913·Journal of Biological Chemistry

Abstract

Though an unusual amount of attention has been devoted to urinary creatinine since the introduction of Folin's simple colorimetric method for its estimation in 1904, relatively little consideration has been given to the supposedly related muscle creatine. The few figures which have been published giving the content of muscle creatine have simply served to indicate that the creatine content of vertebrate muscle is in round numbers .4 per cent., though figures for different animals have shown individual results varying from .3-.5 per cent. We have estimated the creatine concentration of muscle in a number of the common laboratory animals, rabbit, dog, cat, guinea pig, monkey, and likewise in man, in a few instances, where we have been able to obtain good samples at autopsy. Our muscle analyses on 20 normal rabbits and 5 dogs have yielded very uniform figures and indicate that the creatine concentration of rabbit muscle is .52 per cent. and of the dog muscle, .37 per cent. Our data on the muscle of the other...

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Crossref · 10.1016/s0021-9258(18)88617-3

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Metadata

Authors
Myers, V. C., & Fine, M. S.
Venue
Journal of Biological Chemistry
Publisher
Elsevier BV
Published
1913-02
Volume
14
Issue
1
Pages
9-26
ISSN
0021-9258 (ISSN-L)
OpenAlex
W168407574
Cited by
53
References
0
Citations by year
2024: 1 · 2023: 1 · 2022: 1 · 2021: 2 · 2020: 2 · 2019: 1 · 2017: 2 · 2015: 2 · 2014: 1
FWCI
6.86
Type
journal article
Language
en
Open access
Locations
Journal of Biological Chemistry (publishedVersion, cc-by)
Topics
  • Health Sciences › Nursing › Nutrition and Dietetics › Muscle metabolism and nutrition
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Amino Acid Enzymes and Metabolism
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Food Nutrient Composition and Product Development
Keywords
creatine, urinary creatinine, creatine metabolism, rabbit muscle, human muscle

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