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Primary Sequence of U-1 Nuclear Ribonucleic Acid of Novikoff Hepatoma Ascites Cells
Open accessAbstract
The U-1 RNA is one of the low molecular weight nuclear RNAs of Novikoff hepatoma ascites cells that is specifically localized to the extranucleolar portion of the nucleus. After the RNA was purified by polyacrylamide gel electrophoresis, it was subjected to various enzymatic digestion procedures for determination of its primary nucleotide sequence. The U-1 RNA contains 171 nucleotides. Its 5′ end is an alkali-stable tetranucleotide containing N2,2,7-trimethyl guanylic acid. The primary sequence of U-1 RNA is: (m32,2,7G, Am, Um) [see PDF for sequence]
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Cited by
The cap and poly(A) tail function synergistically to regulate mRNA translational efficiency.
Gallie, D. R. (1991) · Genes & Development · doi:10.1101/gad.5.11.2108 · Cited by 868
5′-Terminal 7-methylguanosine in eukaryotic mRNA is required for translation
Muthukrishnan, S., Both, G. W., Furuichi, Y., & Shatkin, A. J. (1975) · Nature · doi:10.1038/255033a0 · Cited by 522
Metadata
- Authors
- Reddy, R., Ro-Choi, T. S., Henning, D., & Busch, H.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1974-10
- Volume
- 249
- Issue
- 20
- Pages
- 6486-6494
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1555556483
- Cited by
- 176
- References
- 0
- FWCI
- 7.28
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- The paper
- Reddy, R., Ro-Choi, T. S., Henning, D., & Busch, H. (1974). Primary Sequence of U-1 Nuclear Ribonucleic Acid of Novikoff Hepatoma Ascites Cells. Journal of Biological Chemistry. https://doi.org/10.1016/s0021-9258(19)42183-2
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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