The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
[α1(III)]3 Human Skin Collagen
Open accessAbstract
Human dermis was digested with pepsin under conditions that maintain the helical conformation of the bulk of the collagen.Molecules containing (rl(II1) chains were separated from [al(I)]& collagen by differential salt precipitation at pH '7.5, with the use of the peptides produced by CNBr cleavage to monitor the composition of each fraction.The isolated molecules are composed of three al(IJ1) chains, and these chains are cross-linked by disulfide bonds.Exposure to dithiothreitol liberates the three apparently identical chains, and these elute on carboxymethylcellulose chromatography at a position intermediate between al(I) and (r2.The pepsin-resistant portion of these chains is the same size as that of previously isolated collagen chains.Human dermis was also digested with CNBr, and resultant al(I) and al(II1) peptides were separated chromatographically.The relative quantities of these peptides indicate that al(II1) chains predominate in early fetal skin, but by birth and in later life al(I) chains are approximately 3 times as plentiful.Collagen extracted from human skin has been well characterized in its chain composition (2) and also at the level of CNBr peptides (3, 4).This molecule is composed of two
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Cites
Action of Proteolytic Enzymes on Tropocollagen and Insoluble Collagen*
Drake, M. P., Davison, P. F., Bump, S., & Schmitt, F. O. (1966) · Biochemistry · doi:10.1021/bi00865a039 · Cited by 257
Cited by
Biochemical characteristics and biological significance of the genetically-distinct collagens
Miller, E. J. (1976) · Molecular and Cellular Biochemistry · doi:10.1007/bf01731779 · Cited by 462
Patients with Ehlers-Danlos syndrome type IV lack type III collagen.
Pope, F. M., Martin, G. R., Lichtenstein, J. R., Penttinen, R., Gerson, B., Rowe, D. W., & McKusick, V. A. (1975) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.72.4.1314 · Cited by 429
Functionality of muscle proteins in gelation mechanisms of structured meat products
Asghar, A., Samejima, K., Yasui, T., & Henrickson, R. L. (1985) · C R C Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398509527408 · Cited by 293
Nusgens, B. V., Colige, A. C., Lambert, C. A., Lapière, C. M., Humbert, P., Rougier, A., Haftek, M., Richard, A., & Creidi, P. (2001) · Journal of Investigative Dermatology · doi:10.1046/j.0022-202x.2001.01362.x · Cited by 262
Collagen types I, III, and V in human embryonic and fetal skin
Smith, L. T., Holbrook, K. A., & Madri, J. A. (1986) · American Journal of Anatomy · doi:10.1002/aja.1001750409 · Cited by 207
Metadata
- Authors
- Epstein, E. H.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1974-05
- Volume
- 249
- Issue
- 10
- Pages
- 3225-3231
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1491757243
- Cited by
- 589
- References
- 1
- FWCI
- 44.48
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
