The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Patients with Ehlers-Danlos syndrome type IV lack type III collagen.
Open accessAbstract
One of the genetically distinct collagens (type III) normally found in skin, aorta, and intestine is missing from the tissues of patients with the Ehlers-Danlos syndrome type IV. While skin fibroblasts from other individuals synthesize both types I and III collagen. Ehlers-Danlos syndrome IV cells synthesize only type I. These results suggest that the fragile skin, blood vessels, and intestines of Ehlers-Danlos syndrome IV patients result from an absence of type III collagen.
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Citations
Cites
[α1(III)]3 Human Skin Collagen
Epstein, E. H. (1974) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)42661-6 · Cited by 589
Chung, E., & Miller, E. J. (1974) · Science · doi:10.1126/science.183.4130.1200 · Cited by 524
Characterization of collagen peptides by sodium dodecylsulfate-polyacrylamide electrophoresis
Furthmayr, H., & Timpl, R. (1971) · Analytical Biochemistry · doi:10.1016/0003-2697(71)90173-4 · Cited by 516
A Heritable Disorder of Connective Tissue: Hydroxylysine-Deficient Collagen Disease
Pinnell, S. R., Krane, S. M., Kenzora, J. E., & Glimcher, M. J. (1972) · New England Journal of Medicine · doi:10.1056/nejm197205112861901 · Cited by 414
Miller, E. J., Epstein, E. H., & Piez, K. A. (1971) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(71)90006-4 · Cited by 291
Defect in Conversion of Procollagen to Collagen in a Form of Ehlers-Danlos Syndrome
Lichtenstein, J. R., Martin, G. R., Kohn, L. D., Byers, P. H., & McKusick, V. A. (1973) · Science · doi:10.1126/science.182.4109.298 · Cited by 257
Self-citationThe Nature of the Collagen Synthesized by Cultured Human Fibroblasts
Layman, D. L., McGoodwin, E. B., & Martin, G. R. (1971) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.68.2.454 · Cited by 239
Self-citationAbnormal collagen metabolism in cultured cells in osteogenesis imperfecta.
Penttinen, R. P. K., Lichtenstein, J. R., Martin, G. R., & McKusick, V. A. (1975) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.72.2.586 · Cited by 184
Self-citationChung, E., Keele, E. M., & Miller, E. J. (1974) · Biochemistry · doi:10.1021/bi00714a006 · Cited by 173
Human aorta collagens: Evidence for three distinct species
Trelstad, R. L. (1974) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(74)90605-6 · Cited by 157
Cited by
International nosology of heritable disorders of connective tissue, Berlin, 1986
Beighton, P., de Paepe, A., Danks, D., Finidori, G., Gedde‐Dahl, T., Goodman, R., Hall, J. G., Hollister, D. W., Horton, W., McKusick, V. A., et al. (1988) · American Journal of Medical Genetics · doi:10.1002/ajmg.1320290316 · Cited by 732
Self-citationThe Biosynthesis of Collagen and Its Disorders
Prockop, D. J., Kivirikko, K. I., Tuderman, L., & Guzman, N. A. (1979) · New England Journal of Medicine · doi:10.1056/nejm197907123010204 · Cited by 574
Biochemical characteristics and biological significance of the genetically-distinct collagens
Miller, E. J. (1976) · Molecular and Cellular Biochemistry · doi:10.1007/bf01731779 · Cited by 462
Diagnosis, natural history, and management in vascular Ehlers-Danlos syndrome
Byers, P. H., Belmont, J., Black, J., De Backer, J., Frank, M., Jeunemaitre, X., Johnson, D., Pepin, M., Robert, L., Sanders, L., et al. (2017) · American Journal of Medical Genetics Part C: Seminars in Medical Genetics · doi:10.1002/ajmg.c.31553 · Cited by 381
Shih, B., & Bayat, A. (2010) · Archives of Dermatological Research · doi:10.1007/s00403-009-1014-y · Cited by 238
Metadata
- Authors
- Pope, F. M., Martin, G. R., Lichtenstein, J. R., Penttinen, R., Gerson, B., Rowe, D. W., & McKusick, V. A.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1975-04
- Volume
- 72
- Issue
- 4
- Pages
- 1314-1316
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2160256489
- Cited by
- 429
- References
- 13
- FWCI
- 12.75
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Patients with Ehlers-Danlos syndrome type IV lack type III collagen. https://app.cochat.ai/papers/10.1073/pnas.72.4.1314
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- Pope, F. M., Martin, G. R., Lichtenstein, J. R., Penttinen, R., Gerson, B., Rowe, D. W., & McKusick, V. A. (1975). Patients with Ehlers-Danlos syndrome type IV lack type III collagen. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.72.4.1314
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
