The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Mitochondrial Superoxide Dismutase
Open accessAbstract
Mitochondria were isolated from chicken liver and were then separated into fractions containing the outer membrane, the soluble components of the intermembrane space, the inner membrane, and the soluble enzymes of the matrix space. The manganosuperoxide dismutase was found primarily in the matrix space whereas the cuprozinc superoxide dismutase, previously isolated from the cytosol, was found in the intermembrane space. No activity was associated with the membranous fractions. A strain of petite mutants of Saccharomyces cerevisiae which lacks mitochondrial DNA, was examined and found to contain both the mangano- and the cuprozinc types of superoxide dismutase. This result indicates that the manganoenzyme, although localized in the mitochondrial matrix, is actually made under the directions of the nuclear genome and that its biosynthesis therefore probably takes place in the cytosol.
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Citations
Cites
Superoxide dismutase: Improved assays and an assay applicable to acrylamide gels
Beauchamp, C., & Fridovich, I. (1971) · Analytical Biochemistry · doi:10.1016/0003-2697(71)90370-8 · Cited by 12,892
Self-citationWeisiger, R. A., & Fridovich, I. (1973) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)43969-0 · Cited by 895
Self-citation
Cited by
How mitochondria produce reactive oxygen species
Murphy, M. P. (2009) · Biochemical Journal · doi:10.1042/bj20081386 · Cited by 8,207
Zelko, I. N., Mariani, T. J., & Folz, R. J. (2002) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)00905-x · Cited by 2,212
Antioxidants in health and disease
Young, I. S., & Woodside, J. V. (2001) · Journal of Clinical Pathology · doi:10.1136/jcp.54.3.176 · Cited by 1,949
Mitochondria and reactive oxygen species
Kowaltowski, A. J., de Souza-Pinto, N. C., Castilho, R. F., & Vercesi, A. E. (2009) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2009.05.004 · Cited by 1,162
Lebovitz, R. M., Zhang, H., Vogel, H., Cartwright, J., Dionne, L., Lu, N., Huang, S., & Matzuk, M. M. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.18.9782 · Cited by 1,023
Metadata
- Authors
- Weisiger, R. A., & Fridovich, I.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1973-07
- Volume
- 248
- Issue
- 13
- Pages
- 4793-4796
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1576198188
- Cited by
- 958
- References
- 2
- FWCI
- 6.14
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
