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Studies of Triglyceride Biosynthesis in Homogenates of Adipose Tissue
Open accessAbstract
The mechanism of triglyceride synthesis has been studied in homogenates of chicken liver (1, 2) and rat liver and several of the reactions have been investigated individually in some detail. Thus, far, however, no studies on the mechanism of triglyceride synthesis in adipose tissue have been reported. In other experiments epinephrine, adrenocorticotropic and glucagon appear to inhibit the esterification of l-C14-palmitate when present during incubation of the epididymal fat pad in vitro an action could explain in part the lipid-mobilizing effects of these hormones. Knowl-edge of the pathways of triglyceride biosynthesis may then be a prerequisite to understanding the mechanism of metabolic and hormonal control of lipid deposition and mobilization.
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Citations
Cited by
Wise, L. S., & Green, H. (1979) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)37913-9 · Cited by 481
A futile metabolic cycle activated in adipocytes by antidiabetic agents
Guan, H.-P., Li, Y., Jensen, M. V., Newgard, C. B., Steppan, C. M., & Lazar, M. A. (2002) · Nature Medicine · doi:10.1038/nm780 · Cited by 428
Jungas, R. L., & Ball, E. G. (1963) · Biochemistry · doi:10.1021/bi00902a035 · Cited by 377
Weight gain and adipose tissue metabolism after smoking cessation in women
Ferrara, C., Kumar, M., Nicklas, B., McCrone, S., & Goldberg, A. (2001) · International Journal of Obesity · doi:10.1038/sj.ijo.0801716 · Cited by 79
Metadata
- Authors
- Steinberg, D., Vaughan, M., Margolis, S., Price, H., & Pittman, R.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1961-06
- Volume
- 236
- Issue
- 6
- Pages
- 1631-1637
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W122779970
- Cited by
- 222
- References
- 0
- FWCI
- 5.48
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Steinberg, D., Vaughan, M., Margolis, S., Price, H., & Pittman, R. (1961). Studies of Triglyceride Biosynthesis in Homogenates of Adipose Tissue. Journal of Biological Chemistry. https://doi.org/10.1016/s0021-9258(19)63276-x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
