The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.
Degradation of type IV (basement membrane) collagen by a proteinase isolated from human polymorphonuclear leukocyte granules.
Open accessAbstract
A serine esterase with potent proteolytic activity against native bovine lens capsule type IV collagen was isolated and purified from extract of human polymorphonuclear leukocytes (PMN). The type IV collagenolytic activity co-purified with N-t-benzyloxycarbonyl-L-alanine nitroanilidase, and was inhibited by phenylmethanesulfonyl fluoride and N-acetyl-Ala-Ala-Ala-Ala chloromethyl ketone. In addition, the purified enzyme had elastolytic activity, reacted with a specific antibody to PMN elastase, and, therefore, appeared to be identical with this enzyme. A simple, reproducible assay for the detection of type IV collagenase activity using insoluble bovine anterior lens capsule collagen was defined. Sodium dodecyl sulfate polyacrylamide gel electrophoresis revealed that the enzyme released large molecular weight peptides (greater than 30,000) from the insoluble substrate. The enzyme was also active against native, pepsin-solubilized type IV collagen; five reaction products could be identified. These data suggest that PMN elastase may be involved in the degradation of basement membrane collagen in physiologic and pathologic states.
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Cites
PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT
Lowry, O., Rosebrough, N., Farr, A. L., & Randall, R. (1951) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)52451-6 · Cited by 317,331
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
LAEMMLI, U. K. (1970) · Nature · doi:10.1038/227680a0 · Cited by 249,961
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Kerr, M. (1978) · Biochemical Education · doi:10.1016/0307-4412(78)90169-3 · Cited by 919
A COLORIMETRIC METHOD FOR THE DETERMINATION OF THE PROTEOLYTIC ACTIVITY OF DUODENAL JUICE
Charney, J., & Tomarelli, R. M. (1947) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)41059-3 · Cited by 721
Human leukocyte granule elastase: rapid isolation and characterization
Baugh, R. J., & Travis, J. (1976) · Biochemistry · doi:10.1021/bi00649a017 · Cited by 539
Liotta, L. A., Abe, S., Robey, P. G., & Martin, G. R. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.5.2268 · Cited by 449
Isolation of a collagen from basement membranes containing three identical α-chains
Kefalides, N. A. (1971) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(71)90073-8 · Cited by 288
Structural studies on human type IV collagen.
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The degradation of articular collagen by neutrophil proteinases
Starkey, P. M., Barrett, A. J., & Burleigh, M. C. (1977) · Biochimica et Biophysica Acta (BBA) - Enzymology · doi:10.1016/0005-2744(77)90066-3 · Cited by 183
The use of p-nitrophenyl N-tert-butyloxycarbonyl-L-alaninate as substrate for elastase
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Cited by
Wiedow, O., Schröder, J. M., Gregory, H., Young, J. A., & Christophers, E. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)77182-2 · Cited by 433
Briggaman, R. A., Schechter, N. M., Fraki, J., & Lazarus, G. S. (1984) · The Journal of experimental medicine · doi:10.1084/jem.160.4.1027 · Cited by 190
Metadata
- Authors
- Mainardi, C. L., Dixit, S. N., & Kang, A. H.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1980-06
- Volume
- 255
- Issue
- 11
- Pages
- 5435-5441
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1583126278
- Cited by
- 277
- References
- 20
- FWCI
- 10.01
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Mainardi, C. L., Dixit, S. N., & Kang, A. H. (1980). Degradation of type IV (basement membrane) collagen by a proteinase isolated from human polymorphonuclear leukocyte granules. Journal of Biological Chemistry. https://doi.org/10.1016/s0021-9258(19)70805-9
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
