The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
A novel lysine-substituted nucleoside in the first position of the anticodon of minor isoleucine tRNA from Escherichia coli.
Open accessAbstract
A minor species of isoleucine tRNA (tRNA(minor Ile)) specific to the codon AUA has been isolated from Escherichia coli B and a modified nucleoside N+ has been found in the first position of the anticodon (Harada, F., and Nishimura, S. (1974) Biochemistry 13, 300-307). In the present study, tRNA(minor Ile)) was purified from E. coli A19, and nucleoside N+ was prepared, by high-performance liquid chromatography, in an amount (0.6) A260 units) sufficient for the determination of chemical structures. By 400 MHz 1H NMR analysis, nucleoside N+ was found to have a pyrimidine moiety and a lysine moiety, the epsilon amino group of which was involved in the linkage between these two moieties. From the NMR analysis together with mass spectrometry, the structure of nucleoside N+ was determined as 4-amino-2-(N6-lysino)-1-(beta-D-ribofuranosyl)pyrimidinium ("lysidine"), which was confirmed by chemical synthesis. Lysidine is a novel type of modified cytidine with a lysine moiety and has one positive charge. Probably because of such a unique structure, lysidine in the first position of anticodon recognizes adenosine but not guanosine in the third position of codon.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Structural studies on a yeast glutamic acid tRNA specific to GAA codon
Yoshida, M., Takeishi, K., & Ukita, T. (1971) · Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis · doi:10.1016/0005-2787(71)90555-7 · Cited by 69
Cited by
The Endosymbiont Hypothesis Revisited
Gray, M. W. (1992) · International Review of Cytology · doi:10.1016/s0074-7696(08)62068-9 · Cited by 586
tRNA’s Wobble Decoding of the Genome: 40 Years of Modification
Agris, P. F., Vendeix, F. A. P., & Graham, W. D. (2007) · Journal of Molecular Biology · doi:10.1016/j.jmb.2006.11.046 · Cited by 543
Summary: the modified nucleosides of RNA
Limbach, P. A., Crain, P. F., & McCloskey, J. A. (1994) · Nucleic Acids Research · doi:10.1093/nar/22.12.2183 · Cited by 523
Björk, G. R., & Hagervall, T. G. (2005) · EcoSal Plus · doi:10.1128/ecosalplus.4.6.2 · Cited by 340
Codon reassignment (codon capture) in evolution
Osawa, S., & Jukes, T. H. (1989) · Journal of Molecular Evolution · doi:10.1007/bf02103422 · Cited by 289
Metadata
- Authors
- Muramatsu, T., Yokoyama, S., Horie, N., Matsuda, A., Ueda, T., Yamaizumi, Z., Kuchino, Y., Nishimura, S., & Miyazawa, T.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1988-07
- Volume
- 263
- Issue
- 19
- Pages
- 9261-9267
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1501954650
- Cited by
- 182
- References
- 1
- FWCI
- 3.81
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: A novel lysine-substituted nucleoside in the first position of the anticodon of minor isoleucine tRNA from Escherichia coli. https://app.cochat.ai/papers/10.1016/s0021-9258(19)76533-8
- The paper
- Muramatsu, T., Yokoyama, S., Horie, N., Matsuda, A., Ueda, T., Yamaizumi, Z., Kuchino, Y., Nishimura, S., & Miyazawa, T. (1988). A novel lysine-substituted nucleoside in the first position of the anticodon of minor isoleucine tRNA from Escherichia coli. Journal of Biological Chemistry. https://doi.org/10.1016/s0021-9258(19)76533-8
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
