Captopril-impaired production of tumor necrosis factor-α–induced interleukin-1β in human monocytes is associated with altered intracellular distribution of nuclear factor-κB
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ACE inhibitors have immune-modulating properties and suppress cytokine production, likely through interference with NF-kB activation.
“ACE inhibitors have immune-modulating properties and suppress cytokine production (e.g. IL-1, TNF-α), likely through interference with NF-κB activation [123].”
From Cognitive remission: a novel objective for the treatment of major depression? (2016) · cites this paper as [123]
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- Authors
- Andersson, P.
- Affiliations
- Karolinska Institutet (SE)
- Venue
- Journal of Laboratory and Clinical Medicine
- Publisher
- Elsevier BV
- Published
- 2002-08
- Volume
- 140
- Issue
- 2
- Pages
- 103-109
- ISSN
- 0022-2143 (ISSN-L)
- OpenAlex
- W2070097306
- Cited by
- 20
- References
- 0
- Citations by year
- 2025: 2 · 2021: 1 · 2016: 3 · 2014: 3 · 2012: 1
- FWCI
- 0.63
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Laboratory and Clinical Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › NF-κB Signaling Pathways
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Inflammasome and immune disorders
- Health Sciences › Medicine › Genetics › Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Keywords
- captopril, IL-1β, TNF-α, monocytes, nuclear factor-kappaB, p65 nuclear translocation, ACE inhibitors, immunomodulation, lipopolysaccharide, pro-IL-1β
- MeSH terms
- Angiotensin-Converting Enzyme Inhibitors, Antineoplastic Agents, Captopril, Dose-Response Relationship, Drug, Humans, Interleukin-1, Monocytes, RNA, Messenger, Tumor Necrosis Factor-alpha, Gene Expression, NF-kappa B, U937 Cells
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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