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Hepatic lipase facilitates the selective uptake of cholesteryl esters from remnant lipoproteins in apoE-deficient mice

Amar, Marcelo J.A., Dugi, Klaus A., Haudenschild, Changting C., Shamburek, Robert D., Foger, Bernhard, Chase, Michael, Bensadoun, Andre, Hoyt, Robert F., Brewer, H. Bryan, Santamarina-Fojo, Silvia·1998·Journal of Lipid Research

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  • Hepatic lipase increases hepatic HDL-CE uptake.

    “It has been shown that the enzyme hepatic lipase (HL) increases hepatic HDL-CE uptake (40-43).”

    From The hepatic WASH complex is required for efficient plasma LDL and HDL cholesterol clearance (2019) · cites this paper as [40]

    The passage indexed as Abstract (page unavailable) suggests that lipolysis may be required for HL-mediated enhanced selective uptake of HDL cholesteryl esters in apoE-deficient mice. It does not establish increased hepatic HDL-CE uptake: the measured increase in liver uptake was from VLDL cholesteryl ester, not HDL. (LLM, conf=0.85)

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Research works printed but not linked: 53

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Metadata

Authors
Amar, M. J. A., Dugi, K. A., Haudenschild, C. C., Shamburek, R. D., Foger, B., Chase, M., Bensadoun, A., Hoyt, R. F., Brewer, H. B., & Santamarina-Fojo, S.
Venue
Journal of Lipid Research
Publisher
Elsevier BV
Published
1998-12
Volume
39
Issue
12
Pages
2436-2442
ISSN
0022-2275
Cited by
54
References
1
Language
en

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