The DOI matches its Crossref record; 58 of the 58 references it cites were found in a registry or an index.
Presence of dolichol and its derivatives in human blood.
Abstract
Optimal conditions for the quantitative estimation of dolichol in human plasma were determined. Because of the large amounts of other lipids present in the blood, the extraction procedure, the procedure for hydrolysis, and the HPLC procedure are of decisive importance. Human plasma contains dolichol, dolichyl esters, and dolichyl phosphate at concentrations of 41, 102, and 55 ng/g, respectively. These polyisoprenoid lipids are associated with the high density lipoprotein fraction. The relative amounts and compositions of dolichyl esters in the plasma are similar to those observed in isolated human liver microsomes and Golgi vesicles. Sixty percent of the fatty acids present are saturated and almost no long-chain polyunsaturated components are present. There is no correlation between blood dolichol content and weight, sex, dietary state, or plasma cholesterol level, but there is an inverse relationship to plasma triglyceride content. A linear increase in the total plasma dolichol content with increasing age was found. In a few pathological conditions where the level of blood cholesterol was increased, the total blood dolichol content was not affected. Apparently, dolichol is a stable lipid component of human high density lipoprotein.
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“comparable to previously published plasma levels ( 43 ).”
From Lipidomics reveals a remarkable diversity of lipids in human plasma (2010) · cites this paper as [43]
In the citing paper
“slightly higher than previously published values ( 43,47,48 ).”
From Lipidomics reveals a remarkable diversity of lipids in human plasma (2010) · cites this paper as [43]
Citations
Cites
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A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES
Folch, J., Lees, M., & Stanley, G. H. S. (1957) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)64849-5 · Cited by 65,189
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The Liver: Biology and Pathobiology
Carey, W., & Fleshler, B. (1983) · JAMA · doi:10.1001/jama.1983.03330310070041 · Cited by 1,479
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ANSELL, G. B., Hawthorne, J. N., & DAWSON, R. M. C. (1973) · Medical Entomology and Zoology · Cited by 1,066
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Research works printed but not linked: 3
- Wolfe, 1987, Dolichols, lysosomal membrane turnover and relationships to the accumulation of ceroid and lipofuscin in inherited diseases, Alzheimer's disease and aging, Chem. Scr., 27, 79
- Pullarkat, 1987, Dolichols and phosphodolichols in aging and in neurological disorders, Chem. Scr., 27, 85
- Haltia, 1987, Infantile neuronal ceroid-lipofuscinosis: an inherited disorder with disturbed dolichol metabolism, Chem. Scr., 27, 89
Cited by
Lipidomics reveals a remarkable diversity of lipids in human plasma
Quehenberger, O., Armando, A. M., Brown, A. H., Milne, S. B., Myers, D. S., Merrill, A. H., Bandyopadhyay, S., Jones, K. N., Kelly, S., Shaner, R. L., et al. (2010) · Journal of Lipid Research · doi:10.1194/jlr.m009449 · Cited by 1,341
Age‐related changes in the lipid compositions of rat and human tissues
Kalén, A., Appelkvist, E., & Dallner, G. (1989) · Lipids · doi:10.1007/bf02535072 · Cited by 425
Self-citationLaaksonen, R., Jokelainen, K., Laakso, J., Sahi, T., Härkönen, M., Tikkanen, M. J., & Himberg, J.-J. (1996) · The American Journal of Cardiology · doi:10.1016/s0002-9149(97)89180-1 · Cited by 171
Metadata
- Authors
- Elmberger, P. G., Engfeldt, P., & Dallner, G.
- Venue
- Journal of Lipid Research
- Publisher
- Elsevier BV
- Published
- 1988-12
- Volume
- 29
- Issue
- 12
- Pages
- 1651-1662
- ISSN
- 0022-2275
- Cited by
- 34
- References
- 58
- Language
- en
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