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Glycemic response to glucagon during fasting hypoglycemia: An aid in the diagnosis of hyperinsulinism
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“An exaggerated glycemic response (>30 mg/dL [>1.7 mmol/L]) is nearly pathognomonic of hyperinsulinism.33”
From Recommendations from the Pediatric Endocrine Society for evaluation and management of persistent hypoglycemia in neonates, infants, and children (2015) · cites this paper as [33]
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“7 mmol/L]) is nearly pathognomonic of hyperinsulinism.(33) Because plasma insulin concentration is sometimes not above the lower limit of detection,(34) it is important to include the following tests when assessing the possibility of hypoglycemia due to hyperinsulinism: plasma BOHB and FFA (both inappropriately low; B…”
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A novel case of compound heterozygous congenital hyperinsulinism without high insulin levels
Brady, C. C., Palladino, A., & Gutmark‐Little, I. (2015) · International Journal of Pediatric Endocrinology · doi:10.1186/s13633-015-0012-4 · Cited by 6
Development of the Pancreas and Neonatal Diabetes
Scharfmann, R., & Hamilton-Shield, J. P. (2007) · Endocrine development · doi:10.1159/isbn.978-3-8055-8386-2 · Cited by 7
Low-Level Mosaic GCK Mutations in Children With Diazoxide-Unresponsive Congenital Hyperinsulinism
Boodhansingh, K. E., Lord, K., Adzick, N. S., Bhatti, T. R., Ganguly, A. A., Stanley, C. A., & León, D. D. D. (2024) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgae713 · Cited by 5
Self-citationCoelho, R. C. L. A., Wells, J. C. K., Symth, J., Semple, R. K., O’Rahilly, S., Eaton, S. D., & Hussain, K. (2007) · Hormone Research in Paediatrics · doi:10.1159/000100974 · Cited by 5
Hypoglycemia in the Toddler and Child
Wolfsdorf, J. I., & Stanley, C. A. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-62520-3.00023-3 · Cited by 5
Self-citationGlucose metabolism and evaluation of hypoglycemia in neonates
Kim, E. Y. (2007) · Korean Journal of Pediatrics · doi:10.3345/kjp.2007.50.3.223 · Cited by 5
Plasma atrial natriuertic peptide concentrations in childen with insulin-dependent diabetes mellitus
Somoyer, W. E., Brouhard, B. H., Ponder, S. W., LaGrone, L., Godsoe, A., & Travis, L. B. (1990) · The Journal of Pediatrics · doi:10.1016/s0022-3476(05)81656-7 · Cited by 5
Hypoglycemic syndrome in infancy and childhood. A surgeon's perspective.
Moossa, A. R., Baker, L., & Lavelle-Jones, M. (1987) · PubMed Central · Cited by 5
Self-citationHypoglycemia in infancy and childhood
Keer, S. (1982) · The Indian Journal of Pediatrics · doi:10.1007/bf02834569 · Cited by 5
Metadata
- Authors
- Finegold, D. N., Stanley, C. A., & Baker, L.
- Affiliations
- Children's Hospital of Philadelphia (US)
- Corresponding author
- Finegold, David N.
- Venue
- The Journal of Pediatrics
- Publisher
- Elsevier BV
- Published
- 1980-02
- Volume
- 96
- Issue
- 2
- Pages
- 257-259
- ISSN
- 0022-3476 (ISSN-L)
- OpenAlex
- W2003513415
- Cited by
- 150
- References
- 12
- Citations by year
- 2026: 2 · 2024: 4 · 2023: 6 · 2022: 4 · 2021: 1 · 2020: 6 · 2019: 5 · 2018: 5 · 2017: 4 · 2016: 6 · 2015: 9 · 2014: 5 · 2013: 6 · 2012: 3
- FWCI
- 9.09
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Pediatrics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Pancreatic function and diabetes
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Metabolism and Genetic Disorders
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Keywords
- hyperinsulinism, fasting hypoglycemia, glucagon stimulation test, glycemic response, insulin secretion, beta-hydroxybutyrate, infants, hypoglycemia diagnosis
- MeSH terms
- Blood Glucose, Child, Child, Preschool, Female, Glucagon, Humans, Hyperinsulinism, Hypoglycemia, Infant, Infant, Newborn, Male
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