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AGGREGATION AS A FACTOR INFLUENCING THE TOXICITY OF SYMPATHOMIMETIC AMINES IN MICE
Abstract
1. Aggregation influences the toxicity of sympathomimetic amines in mice. 2. As the area per mouse increases, the toxicity decreases for mice confined in a group. 3. If the area per mouse is kept. constant at approximately 50 sq. cm., the presence of [9] other mice markedly increases the toxicity of these drugs. 4. Environmental temperature greatly influences the degree of mutual excitation and thus modifies the effect of aggregation on toxicity.
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Metadata
- Authors
- CHANCE, M. R. A.
- Venue
- The Journal of Pharmacology and Experimental Therapeutics
- Publisher
- Elsevier BV
- Published
- 1946-07
- Volume
- 87
- Issue
- 3
- Pages
- 214-219
- ISSN
- 0022-3565 (ISSN-L)
- OpenAlex
- W2285050182
- Cited by
- 191
- References
- 0
- FWCI
- 2.70
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: AGGREGATION AS A FACTOR INFLUENCING THE TOXICITY OF SYMPATHOMIMETIC AMINES IN MICE. https://app.cochat.ai/papers/10.1016/s0022-3565(25)05986-5
- The paper
- CHANCE, M. R. A. (1946). AGGREGATION AS A FACTOR INFLUENCING THE TOXICITY OF SYMPATHOMIMETIC AMINES IN MICE. The Journal of Pharmacology and Experimental Therapeutics. https://doi.org/10.1016/s0022-3565(25)05986-5
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