Cited by 314Receptor Mechanisms and SignalingNeuroscience and Neuropharmacology ResearchNeurotransmitter Receptor Influence on Behavior

The DOI matches its Crossref record.

Heterogeneity of presynaptic muscarinic receptors regulating neurotransmitter release in the rat brain

Raiteri, M, Leardi, R, Marchi, M·1984·The Journal of Pharmacology and Experimental Therapeutics

DOI 10.1016/s0022-3565(25)21528-2

Open this paper in CoChat — free account

Abstract

The existence of multiple muscarinic receptors in the brain was investigated by using neurotransmitter release as a functional parameter and by comparing the effects of agonists and antagonists on three systems of release regulation mediated by presynaptic muscarinic receptors. The receptors selected as models for our experiments were: 1) the muscarinic autoreceptors mediating inhibition of acetylcholine release in the cortex; 2) the muscarinic autoreceptors present in the nerve endings of the hippocampus; and 3) the muscarinic presynaptic receptors mediating potentiation of striatal dopamine release (heteroreceptors). The experiments were performed by using rat brain synaptosomes in superfusion. Acetylcholine, oxotremorine and carbachol inhibited the release of [3H]acetylcholine evoked by 15 mM KCI in cortex and hippocampus and potentiated the K+-evoked [3H]dopamine release in the striatum. The concentration-response curves were similar in the three systems, the rank of potency being: acetylcholine greater than oxotremorine greater than carbachol. The effects of acetylcholine were counteracted by several muscarinic antagonists with different rank of potencies and different potency ratios. In particular, the rank of potencies for the drugs tested was: atropine greater than secoverine greater than stercuronium greater than pirenzepine at the autoreceptors, both in cortex and hippocampus; but it was: atropine greater than pirenzepine = secoverine greater than stercuronium, at the heteroreceptors in the striatum. Pirenzepine was 100 times more potent on heteroreceptors than on autoreceptors. Our results suggest the possibility of a differential activation or blockade of central muscarinic receptors by selective drugs.

Integrity signals

Registry

Crossref · 10.1016/s0022-3565(25)21528-2

Cites

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Sorted by citations

Items 201–300 of 314

Acetylcholine Measurement of Cerebrospinal Fluid by In Vivo Microdialysis in Freely Moving Rats
Togashi, H., Matsumoto, M., Yoshioka, M., et al. (1994) · The Japanese Journal of Pharmacology · doi:10.1254/jjp.66.67 · Cited by 16
Nicotinic autoreceptor function in rat brain during maturation and aging: possible differential sensitivity to organophosphorus anticholinesterases
Wu, Y., Harp, P. R., Yan, X.-R., & Pope, C. (2002) · Chemico-Biological Interactions · doi:10.1016/s0009-2797(02)00121-7 · Cited by 15
Competitive interaction of pirenzepine with rat brain muscarinic acetylcholine receptors
El‐Fakahany, E. E., Cioffi, C. L., Abdellatif, M., et al. (1986) · European Journal of Pharmacology · doi:10.1016/0014-2999(86)90577-7 · Cited by 16
Dopamina: síntesis, liberación y receptores en el Sistema Nervioso Central.
Departamento de Fisiología, B. Y. N., Bahena-Trujillo, R., Flores, G., et al. (2000) · REVISTA BIOMÉDICA · doi:10.32776/revbiomed.v11i1.218 · Cited by 15
“glutamato, acetilcolina y serotonina (43,46,47).”
Muscarine-binding sites localized to cortical dopamine terminals
Liskowsky, D. R., & Potter, L. T. (1985) · Neuroscience Letters · doi:10.1016/0304-3940(85)90169-7 · Cited by 15
Facilitation of amphetamine-induced rotation by muscarinic antagonists is correlated with M2 receptor affinity
Hagan, J. J., Tonnaer, J. A. D. M., Rijk, H., et al. (1987) · Brain Research · doi:10.1016/s0006-8993(87)80021-5 · Cited by 15
The neurobiological effects of colchicine: Modulation by nerve growth factor
Barone, S., Bonner, M. J., Tandon, P., McGinty, J. F., & Tilson, H. A. (1992) · Brain Research Bulletin · doi:10.1016/0361-9230(92)90188-4 · Cited by 15
Presynaptic muscarinic cholinergic receptors in the dorsal hippocampus regulate behavioral inhibition of preweanling rats
Takahashi, L. K., & Goh, C.-S. (1996) · Brain Research · doi:10.1016/0006-8993(96)00684-1 · Cited by 14
Antidiuretic Effects of Alpha- and Beta-Adrenoceptor Agonists Microinjected into the Hypothalamic Paraventricular Nucleus in a Water-Loaded and Ethanol-Anesthetized Rat
Tsushima, H., Mori, M., & MATSUDA, T. (1986) · The Japanese Journal of Pharmacology · doi:10.1254/jjp.40.319 · Cited by 15
Specific Phospholipid Modulation by Muscarinic Signaling in a Rat Lesion Model of Alzheimer’s Disease
Llorente‐Ovejero, A., Martínez‐Gardeazabal, J., Moreno‐Rodríguez, M., Lombardero, L., Román, E. G. D. S., Manuel, I., Giralt, M. T., & Rodríguez‐Puertas, R. (2021) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.1c00169 · Cited by 13
Psychiatry and Neuroscience Update
Perez‐Lloret, S., Peralta, M. C., & Barrantes, F. J. (2015) · Springer eBooks · doi:10.1007/978-3-319-17103-6 · Cited by 16
Quinpirole attenuates striatal c-fos induction by 5-HT, opioid and muscarinic receptor agonists
Cook, D. F., & Wirtshafter, D. (1998) · European Journal of Pharmacology · doi:10.1016/s0014-2999(98)00184-8 · Cited by 14
Decreased (3H) quinuclidinyl benzilate binding to lymphocytes in Gilles de la Tourette syndrome
Rabey, J. M., Lewis, A., Graff, E., et al. (1992) · Biological Psychiatry · doi:10.1016/0006-3223(92)90115-g · Cited by 14
Intermittent morphine treatment causes a protracted increase in cholinergic striatal neurotransmission measured ex vivo
Schoffelmeer, A. N. M., Nestby, P., Tjon, G. H. K., Wardeh, G., Vries, T. J. D., Vanderschuren, L. J. M. J., & Mulder, A. H. (1995) · European Journal of Pharmacology · doi:10.1016/0014-2999(95)00588-7 · Cited by 14
Decreased striatal release of acetylcholine following withdrawal from long-term treatment with haloperidol: Modulation by cholinergic, dopamine-D1 and -D2 mechanisms
Friedman, E., Wang, H. Y., & Butkerait, P. (1990) · Neuropharmacology · doi:10.1016/0028-3908(90)90065-y · Cited by 14
Modulation by muscarine and opioid receptors of acetylcholine release in slices from striato-striatal grafts in the rat
Wichmann, T., & Starke, K. (1990) · Brain Research · doi:10.1016/0006-8993(90)91380-y · Cited by 14
Regulation of putative muscarinic cholinergic receptor subtypes in rat brain
Norman, A. B., Battaglia, G., & Creese, I. (1986) · Neurochemistry International · doi:10.1016/0197-0186(86)90071-9 · Cited by 14
GABA-gated chloride channel mutation (Rdl) induces cholinergic physiological compensation resulting in cross resistance in Drosophila melanogaster
Xie, N., Bickley, B. A., & Gross, A. D. (2024) · Pesticide Biochemistry and Physiology · doi:10.1016/j.pestbp.2024.105972 · Cited by 13
Involvement of Septal Muscarinic Receptors in Cholinergically Mediated Changes in Rat Rearing Activity
Monmaur, P. (1997) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(97)00282-7 · Cited by 13
Age-Related Alterations In Pre-Synaptic and Receptor-Mediated Cholinergic Functions In Rat Brain
Buyukuysal, R. L., Ulus, İ. H., & Kiran, B. K. (1998) · Neurochemical Research · doi:10.1023/a:1022403308819 · Cited by 13
“It is known since three decades that ACh release from cholinergic nerve endings can be modulated by muscarinic receptors (30-33).”
Background
Autoradiographic localization of functional muscarinic receptors in the rat superior cervical sympathetic ganglion reveals an extensive distribution over non-synaptic surfaces of neuronal somata, dendrites and nerve endings
Ramcharan, E. J., & Matthews, M. R. (1996) · Neuroscience · doi:10.1016/0306-4522(95)00478-5 · Cited by 13
Effects of serotonergic denervation on the density and plasticity of brain muscarinic receptors in the rat
Alonso, R., & Soubrié, P. (1991) · Synapse · doi:10.1002/syn.890080105 · Cited by 13
“Additionally, from lesion and release experiments, it has been suggested that M2 receptors are preferentially located on cholinergic terminals and control acetylcholine release (Raiteri et al., 1984; Mash et al., 1985; Lapchak et al., 1989; Vickroy and Cadman, 1989; Richards, 1990).”
Background
Effect of BM-5, a presynaptic antagonist-postsynaptic agonist, on cortical acetylcholine release
Casamenti, F., Cosi, C., & Pepeu, G. (1986) · European Journal of Pharmacology · doi:10.1016/0014-2999(86)90116-0 · Cited by 13
Presynaptic Muscarinic Receptors Reduce Synaptic Depression and Facilitate its Recovery at Hippocampal GABAergic Synapses
Gonzalez, J., Lignani, G., Maroto, M., Baldelli, P., & Hernández-Guijo, J. M. (2013) · Cerebral Cortex · doi:10.1093/cercor/bht032 · Cited by 12
Altered fronto-striatal functions in the Gdi1-null mouse model of X-linked Intellectual Disability
Morè, L., Künnecke, B., Yekhlef, L., et al. (2017) · Neuroscience · doi:10.1016/j.neuroscience.2016.12.043 · Cited by 12
Acetylcholine-dopamine balance in striatum: Is it still a target for antiparkinsonian therapy?
Calabresi, P., Stefani, A., Mercuri, N. B., et al. (1989) · Proceedings of the Fourth International Symposium on Polarization Phenomena in Nuclear Reactions · doi:10.1007/978-3-0348-9138-7_31 · Cited by 12
Effects of TRH and DN-1417 on high potassium-evoked acetylcholine release from rat basal forebrain slices determined directly by radioimmunoassay
Suzuki, T., Fujimoto, K., 大畑, 尚., et al. (1989) · General Pharmacology The Vascular System · doi:10.1016/0306-3623(89)90023-2 · Cited by 12
Antagonism by cholinomimetic drugs of the turning induced by intrastriatal pirenzepine in mice
Worms, P., & Bizière, K. (1987) · Psychopharmacology · doi:10.1007/bf00207240 · Cited by 12
“1985), an effect which is blocked by pirenzepine (Raiteri et al. 1984; Schoffelmeer et al. 1986).”
Background
Activation of muscarinic receptors on striatal synaptosomes increases the release of endogenous dopamine
Bonanno, G., Marchi, M., & Raiteri, M. (1985) · Neuropharmacology · doi:10.1016/0028-3908(85)90083-8 · Cited by 12
Self-citation
Chapter 21 Pharmacological muscarinic receptor subtypes
Ladinsky, H., Schiavi, G. B., Monferini, E., et al. (1990) · Progress in brain research · doi:10.1016/s0079-6123(08)60903-6 · Cited by 12
Decreased dopamine uptake into platelet storage granules in Gilles de la Tourette disease
Rabey, J. M., Oberman, Z., Graff, E., et al. (1995) · Biological Psychiatry · doi:10.1016/0006-3223(94)00234-t · Cited by 11
Presynaptic effects of methoctramine on release of acetylcholine
Törőcsik, A., & Vizi, E. S. (1991) · Neuropharmacology · doi:10.1016/0028-3908(91)90157-7 · Cited by 11
Presynaptic muscarinic receptor activation enhances striatal dopamine release evoked by depolarization but not that induced by non-depolarizing stimuli
Marchi, M., Paudice, P., Bonanno, G., et al. (1985) · Neurochemistry International · doi:10.1016/0197-0186(85)90018-x · Cited by 11
Self-citation
Effect of buflomedil (4-(1-pyrrolidinyl)-1-(2,4,6-trimethoxy phenyl)-1-butanone hydrochloride) on the function of striatal dopaminergic neurons.
Hirohumi, K. O. D. A., Hashimoto, T., & Kuriyama, K. (1989) · The Japanese Journal of Pharmacology · doi:10.1254/jjp.49.215 · Cited by 11
Muscarinic receptor-mediated regulation of OM-853-enhanced dopamine release in striatum of rat
Hirohumi, K. O. D. A., Hashimoto, T., & Kuriyama, K. (1989) · European Journal of Pharmacology · doi:10.1016/0014-2999(89)90341-5 · Cited by 11
Effects of JO 1784, A selective sigma ligand, on the autoradiographic localization of M2 and M2 muscarinic receptor subtypes in trimethyltin treated rats
Earley, B. (1995) · Neurochemistry International · doi:10.1016/0197-0186(95)00004-r · Cited by 10
Regulation of Extracellular Dopamine: Release and Uptake
Sulzer, D., Cragg, S. J., & Rice, M. E. (2016) · Handbook of behavioral neuroscience · doi:10.1016/b978-0-12-802206-1.00019-2 · Cited by 10
Radiation-induced increases in sensitivity of cataleptic behavior to haloperidol: Possible involvement of prostaglandins
Joseph, J. A., Kandasamy, S. B., Hunt, W. A., et al. (1988) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(88)90166-9 · Cited by 10
Presynaptic muscarinic and α‐adrenoceptor‐mediated regulation of GABA release from my enteric neurones of the guinea‐pig small intestine
Hashimoto, S., Tanaka, C., & Taniyama, K. (1986) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1986.tb11183.x · Cited by 10
Dissociated cingulate cortical neurons: morphology and muscarinic acetylcholine receptor binding properties
Vogt, B., Townes‐Anderson, E., & Dl, B. (1987) · Journal of Neuroscience · doi:10.1523/jneurosci.07-04-00959.1987 · Cited by 9
Effects of muscarinic receptor agonists and antagonists on rat brain serotonergic activity
Bhattacharya, S. K., & Sen, A. P. (1992) · Journal of Neural Transmission · doi:10.1007/bf01250965 · Cited by 9
Involvement of M2 and non-M2 muscarinic receptors in hippocampal theta rhythm induced by carbachol infusion into the septum of the rat
Monmaur, P., Puma, C., & Sharif, A. (1994) · Brain Research · doi:10.1016/0006-8993(94)91385-4 · Cited by 9
Is the muscarinic receptor that mediates potentiation of dopamine release negatively coupled to the cyclic GMP system?
Marchi, M., Paudice, P., Gemignani, A., et al. (1987) · Journal of Neuroscience Research · doi:10.1002/jnr.490170208 · Cited by 9
Self-citation
Inhibition mediated by group III metabotropic glutamate receptors regulates habenula activity and defensive behaviors
Ostenrath, A. M., Faturos, N., Çobanoğlu, Y. I. Ç., Serneels, B., Jeong, I., Dayanc, E. D., Enz, A., Hinrichsen, F., Mutlu, A. K., Bardenhewer, R., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-62115-z · Cited by 8
“Besides GABA, neuromodulators such as dopamine 41 , serotonin 42 – 45 and acetylcholine 46,47 were also shown to mediate inhibition through their speci ﬁ c inhibitory receptors.”
Acetylcholine Neurotransmitter Receptor Densities in the Striatum of Hemiparkinsonian Rats Following Botulinum Neurotoxin-A Injection
Mann, T., Zilles, K., Klawitter, F., Cremer, M., Hawlitschka, A., Palomero‐Gallagher, N., Schmitt, O., & Wree, A. (2018) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2018.00065 · Cited by 8
Pharmacological properties of presynaptic muscarinic receptors in the sixth abdominal ganglion of the cockroach, Periplaneta americana L.
Corronc, H. L., & Hue, B. (1991) · Pesticide Science · doi:10.1002/ps.2780330209 · Cited by 8
Cholinergic modulation of dopamine release in corpus striatum and substantia nigra of the rat
Marchi, M., Volpe, G., Augliera, A., et al. (1992) · Neurochemistry International · doi:10.1016/0197-0186(92)90251-l · Cited by 8
Self-citation
The selective m1 muscarinic antagonist MT-7 blocks pilocarpine-induced striatal Fos expression
Wirtshafter, D. (2006) · Brain Research · doi:10.1016/j.brainres.2006.02.022 · Cited by 8
Role of dopamine D1 receptors in the striatal and cortical fos expression induced by the muscarinic agonist pilocarpine
Wirtshafter, D. (2004) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2004.02.025 · Cited by 8
Effects of muscarinic receptor agonists and antagonists on dopamine-mediated behavioural paradigms
Bhattacharya, S. K., & Sen, A. P. (1991) · Journal of Neural Transmission · doi:10.1007/bf01244975 · Cited by 8
[3]PIRENZEPINE BINDING IN RAT CORPUS STRIATUM DECREASES AFTER HEMITRANSECTION OF THE NIGRO‐STRIATAL PATHWAY
Pittaluga, A., Versace, P., Marchi, M., et al. (1987) · Fundamental and Clinical Pharmacology · doi:10.1111/j.1472-8206.1987.tb00569.x · Cited by 8
Self-citation
Blockade of M1 muscarinic acetylcholine receptors modulates the methamphetamine-induced psychomotor stimulant effect
Lee, K.-W., Tian, Y., You, I., Kwon, S., Ha, R.-R., Lee, S., Kim, H.-C., & Jang, C. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.02.021 · Cited by 7
Enhancement of cerebral cortical acetylcholine release by intraperitoneal acetic acid and its suppression by analgesics in freely moving rats
Harada, H., Hosonuma, K., Fujii, T., et al. (2000) · Neuroscience Letters · doi:10.1016/s0304-3940(00)01013-2 · Cited by 7
Correlative Motor Behavioral and Striatal Dopaminergic Alterations Induced by 56Fe Radiation
Joseph, J. A., Hunt, W. A., Rabin, B. M., et al. (1988) · Springer eBooks · doi:10.1007/978-1-4613-1567-4_41 · Cited by 7
Muscarinic potentiation of excitatory amino acid‐evoked dopamine release in mesencephalic cells: Specificity for the NMDA response and role of intracellular messengers
Allaoua, H., Chaudieu, I., Alonso, R., et al. (1993) · Synapse · doi:10.1002/syn.890150105 · Cited by 7
Cholinergic Modulation of Gabaergic Efferent Striatal Neurons
Mavridis, M., Kayadjanian, N., & Besson, M. J. (1994) · Advances in behavioral biology · doi:10.1007/978-1-4613-0485-2_45 · Cited by 7
Effect of vinconate on the extracellular levels of dopamine and its metabolites in the rat striatum: microdialysis studies
Iino, T., Katsura, M., & Kuriyama, K. (1995) · European Journal of Pharmacology · doi:10.1016/0014-2999(95)00545-v · Cited by 6
mTOR Involvement in the Mechanisms of Memory
Giovannini, M. G., & Lana, D. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802733-2.00018-9 · Cited by 7
Subtype specificity of the muscarinic receptor-stimulated GTPase response in the rat cortex
Ghodsi-Hovsepian, S., Messer, W. S., & Hoss, W. P. (1990) · Neuroscience Letters · doi:10.1016/0304-3940(90)90803-h · Cited by 6
Regulation of Extracellular Dopamine
Sulzer, D., Zhang, H., Benoit‐Marand, M., & Gonon, F. (2010) · Handbook of behavioral neuroscience · doi:10.1016/b978-0-12-374767-9.00017-2 · Cited by 8
Subtypes of Muscarinic Cholinergic Receptors
Wolfe, B. B. (1989) · Humana Press eBooks · doi:10.1007/978-1-4612-4498-1_4 · Cited by 6
Subtypes of muscarinic receptors in vagal inhibitory pathway to the lower esophageal sphincter of the opossum
Gilbert, R. J., & Dodds, W. J. (1987) · Digestive Diseases and Sciences · doi:10.1007/bf01300200 · Cited by 6
Interaction of choline with muscarine receptor-stimulated phosphoinositide metabolism in the rat brain
Costa, L. G., Kaylor, G., & Murphy, S. D. (1986) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/bf00569398 · Cited by 5
Intrastriatal kainic acid elicits functional supersensitivity of muscarinic receptors regulating dopamine release
Versace, P., Bocchieri, P., Marchi, M., et al. (1987) · Neurochemistry International · doi:10.1016/0197-0186(87)90008-8 · Cited by 5
Self-citation
Muscarinic autoreceptors are differentially affected by selective muscarinic antagonists in rat hippocampus
Gulya, K., Budai, D., & Kása, P. (1989) · Neurochemistry International · doi:10.1016/0197-0186(89)90094-6 · Cited by 5
Effects of repeated administration of tetrahydroaminoacridine (THA) on muscarinic receptor subtypes in the rat brain
Alonso, R., Kan, J. P., Worms, P., et al. (1990) · Neurochemistry International · doi:10.1016/0197-0186(90)90028-r · Cited by 5
Two Drug Binding Sites on Muscarinic Receptors
Birdsall, N. J. M., Hulme, E. C., Krömer, W., et al. (1986) · doi:10.1007/978-1-349-08639-9_9 · Cited by 5
Muscarinic receptor agonist-mediated modulation of neuronal activity in rat cerebral cortex
Lin, Y., & Phillis, J. W. (1991) · European Journal of Pharmacology · doi:10.1016/0014-2999(91)90663-b · Cited by 4
Effects of scopolamine treatment and lesion of the nucleus basalis upon various cholinergic markers in the rat brain cortex
Moret, C., Pastrie, I., & Briley, M. (1989) · Neurochemistry International · doi:10.1016/0197-0186(89)90141-1 · Cited by 4
Carbachol-phorbol ester interactions at muscarinic receptors modulating dopamine release from rabbit striatal slices
Cubeddu, L. X., Hoffmann, I., Talmaciu, R. K., et al. (1991) · Neuroscience Letters · doi:10.1016/0304-3940(91)90624-3 · Cited by 4
Effects of Acetylethylcholine Mustard on [3H]Quinuclidinyl Benzilate Binding and Acetylcholine Release in Rat Brain Synaptosomes
Meyer, E. M., Otero, D. H., Morgan, E., et al. (1987) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1987.tb04117.x · Cited by 4
“In the rat cerebral cortex, these receptors appear to be predominantly the M2 type, based on their pirenzepine insensitivity and on the efficacy of oxotremorine (Raiteri et al., 1984; Meyer and Otero, 1985).”
Background
Biochemical and behavioral characterization of a novel cholinergic agonist, SR 95639
Boast, C. A., Leventer, S. M., Sabb, A. L., et al. (1991) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(91)90181-z · Cited by 4
Neurochemical and Psychopharmacological Assessment of the M1-Selective Agonist AF102B (FKS-508)
Mizobe, F., Nakahara, N., Ogane, N., et al. (1990) · Advances in behavioral biology · doi:10.1007/978-1-4684-5847-3_71 · Cited by 4
Muscarinic Acetylcholine Receptors
Wess, J. (2007) · Wiley eBooks · doi:10.1002/9780470101001.hcn005 · Cited by 4
Atropine restores retinal glutamate / γ-aminobutyric acid levels in vitro in an experimental chick model of myopia
Lloyd, J. T., Collins, A., Phillips, J. R., et al. (2025) · Vision Research · doi:10.1016/j.visres.2025.108656 · Cited by 3
Muscarinic and Nicotinic Receptors in Alzheimer’s Disease: Rationale for Cholinergic Drug Treatment
Lapchak, P. A., Araujo, D. M., & Quirion, R. (1989) · Advances in behavioral biology · doi:10.1007/978-1-4684-5727-8_6 · Cited by 3
PREJUNCTIONAL ACTIONS OF TACRINE ON AUTONOMIC NEUROEFFECTOR TRANSMISSION IN RABBIT ISOLATED PULMONARY ARTERY AND RAT ISOLATED ATRIA
Fabiani, M. E., Kabo, P., & Story, D. (1992) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/j.1440-1681.1992.tb00516.x · Cited by 3
“With respect to our findings with rat atria, it has been established that acetylcholine released from cholinergic nerves in the hearts of a number of species may activate prejunctional muscarinic cholinoceptors and thereby inhibit transmitter release (Bourdois & Mitchell 1974; Szerb & Somogyi 1977; Marchi et al. 1981;…”
Result
Interaction of a Muscarinic Cholinergic Agonist on Acetylcholine and Dopamine Receptors in the Monkey Brain Studied with Positron Emission Tomography
Hartvig, P., Nordberg, A. K., Torstenson, R., et al. (2002) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000057697 · Cited by 3
Acetylcholine
Digala, L. P., Murala, S., & Bollu, P. C. (2022) · Springer eBooks · doi:10.1007/978-3-031-07897-2_11 · Cited by 3
Behavioral correlates of presynaptic events in the cholinergic neurotransmitter system
Russell, R. W. (1988) · Birkhäuser Basel eBooks · doi:10.1007/978-3-0348-9154-7_3 · Cited by 3
Discriminative stimulus properties of NIK-247 and tetrahydroaminoacridine, centrally active cholinesterase inhibitors, in rats
Yamamoto, T., Ohno, M., Sugimachi, K., et al. (1993) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(93)90004-d · Cited by 3
Muscarinic Autoreceptors of Torpedo Electric Organ Are of the M1 Subtype: Evidence by Radioligand Binding Using Selective Antagonists
Green, A. C., & Dowdall, M. J. (1992) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1992.tb09746.x · Cited by 3
Loss of muscarinic regulation of striatal dopamine function in senescence
Joseph, J. A., & Roth, G. S. (1992) · Neurochemistry International · doi:10.1016/0197-0186(92)90244-l · Cited by 3
Inhibition mediated by group III mGluRs regulates habenula activity and defensive behaviorsPreprint
Ostenrath, A. M., Faturos, N., Çobanoğlu, Y. I. Ç., Serneels, B., Jeong, I., Enz, A., Hinrichsen, F., Mutlu, A. K., Bardenhewer, R., Jetti, S. K., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.09.11.612421 · Cited by 3
“Besides GABA, neuromodulators such as dopamine ( 41 ), serotonin ( 42-45 ) and acetylcholine ( 46, 47 ) were also shown to mediate inhibition through their specific inhibitory receptors.”
Background
Release in vitro as a model to study neurotransmitter receptors
Raiteri, M. (1987) · Pharmacological Research Communications · doi:10.1016/0031-6989(87)90042-7 · Cited by 2
Self-citation
Presynaptic Receptors Modulating Transmitter Release: Physiological and Pharmacological Aspects
Raiteri, M., Marchi, M., Maura, G., Bonanno, G., Pittaluga, A., Paudice, P., Gemignani, A., Pende, M., & Drago, C. (1992) · Pharmacochemistry library · doi:10.1016/b978-0-444-88931-7.50011-6 · Cited by 2
Self-citation
Muscarinic receptor-mediated inhibition of dopaminergic excitatory input to caudate neurons from the substantia nigra.
Nabatame, H., Sasa, M., Takaori, S., et al. (1988) · The Japanese Journal of Pharmacology · doi:10.1254/jjp.46.387 · Cited by 2
AF102B: Preclinical Experience
Iga, Y., Ogane, N., Saito, Y., et al. (1991) · Birkhäuser Boston eBooks · doi:10.1007/978-1-4899-6738-1_39 · Cited by 2
Regulation of Dopamine Release by Muscarinic Receptors
Raiteri, M., Marchi, M., Pittaluga, A., et al. (1988) · Palgrave Macmillan UK eBooks · doi:10.1007/978-1-349-10047-7_25 · Cited by 1
Self-citation
Neuropsychiatric Symptoms Related to Cholinergic Deficits in Parkinson’s Disease
Perez‐Lloret, S., Peralta, M. C., & Barrantes, F. J. (2017) · Springer eBooks · doi:10.1007/978-3-319-53126-7_27 · Cited by 1
“function partly as inhibitory autoreceptors on cholinergic terminals [23].”
Background
Presynaptic Cholinergic Mechanisms in Human Cerebral Cortex of Adult and Aged Patients
Marchi, M., Besana, E., Codignola, A., et al. (1991) · Birkhäuser Boston eBooks · doi:10.1007/978-1-4899-6738-1_11 · Cited by 1
Self-citation
Muscarinic Receptors: Molecular Biology and Neuropsychopharmacology
Richelson, E. (1992) · Advances in behavioral biology · doi:10.1007/978-1-4615-3432-7_1 · Cited by 1
Subtypes of muscarinic receptors in cultured explants of the hippocampus of the rat
Waser, P. G. (1987) · Neuropharmacology · doi:10.1016/0028-3908(87)90082-7 · Cited by 1
Muscarinic receptors on cultured cells of rat hippocampus: cholinergic regulation and presence of subtypes
Rimvall, K., Keller, F., & Waser, P. G. (1989) · European Journal of Pharmacology · doi:10.1016/0014-2999(89)90647-x · Cited by 1
Factors influencing the calculation of results from studies of the release of tritiated neurotransmitters from superfused slices of guinea pig striata
Dawson, R. M. (1989) · Journal of Pharmacological Methods · doi:10.1016/0160-5402(89)90036-3 · Cited by 1
Effect of vinconate, an indolonaphthyridine derivative, on metabolism and function of cerebral cholinergic neurons in rat
Iino, T., Katsura, M., & KURIYAMA, K. (1993) · Neurochemistry International · doi:10.1016/0197-0186(93)90123-m · Cited by 1
Picric acid-evoked release of [14C]acetylcholine from the isolated synaptosome of rat cerebral cortex
Lin, C. J., & Cheng, J. (1986) · Neuroscience Letters · doi:10.1016/0304-3940(86)90504-5 · Cited by 1
Muscarinic Receptor-Mediated Inhibition of Dopaminergic Excitatory Input to Caudate Neurons from the Substantia Nigra
Nabatame, H., Sasa, M., Takaori, S., et al. (1988) · The Japanese Journal of Pharmacology · doi:10.1016/s0021-5198(19)43292-7 · Cited by 1
Cholinergic Mechanisms in Schizophrenia
Raedler, T. J., & Freedman, R. (2009) · Springer eBooks · doi:10.1007/978-0-387-30410-6_2 · Cited by 1
Modulation of acetylcholine release in rat striatal slices by muscarinic receptors which do not desensitize
PRADODECARVALHO, L. (1989) · Neurochemistry International · doi:10.1016/0197-0186(89)90070-3

Authors: Raiteri, M., Leardi, R., & Marchi, M.
ORCID: Leardi, R
Marchi, M
Venue: The Journal of Pharmacology and Experimental Therapeutics
Publisher: Elsevier BV
Published: 1984-01
Volume: 228
Issue: 1
Pages: 209-214
ISSN: 0022-3565 (ISSN-L)
DOI: 10.1016/s0022-3565(25)21528-2
OpenAlex: W1927364971
Cited by: 314
References: 0
Citations by year: 2025: 3 · 2024: 2 · 2022: 1 · 2021: 2 · 2018: 2 · 2017: 5 · 2016: 5 · 2015: 4 · 2013: 4 · 2012: 4
FWCI: 8.35
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Journal of Pharmacology and Experimental Therapeutics (publishedVersion)
PubMed (publishedVersion)
PubMed
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Receptor Mechanisms and Signaling
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Keywords: presynaptic muscarinic receptors, muscarinic autoreceptors, neurotransmitter release, acetylcholine release, dopamine release, striatum, hippocampus, cerebral cortex, oxotremorine, carbachol, pirenzepine, atropine, antimuscarinic agents, receptor heterogeneity
MeSH terms: Acetylcholine, Animals, Brain, Cerebral Cortex, Corpus Striatum, Dopamine, Hippocampus, Male, Parasympatholytics, Parasympathomimetics, Rats, Inbred Strains, Receptors, Muscarinic, Synaptosomes, Time Factors, Neurotransmitter Agents, Rats, In Vitro Techniques

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Heterogeneity of presynaptic muscarinic receptors regulating neurotransmitter release in the rat brain

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cited by

Related

Metadata

Record

About these checks