IN VIVO INHIBITION OF DOPAMINE β-HYDROXYLASE BY 1-PHENYL-3-(2-THIAZOLYL)-2-THIOUREA (U-14,624)
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PTU has been shown to interfere not only with tyrosinase but also with other enzymes, such as thyroid peroxidase and dopamine beta-hydroxylase.
“For example, PTU has been shown to interfere not only with tyrosinase (the enzyme that catalyses the production of melanin)1011, but also with other enzymes, such as thyroid peroxidase12 and dopamine beta-hydroxylase13.”
From A crystal-clear zebrafish for in vivo imaging (2016) · cites this paper as [13]
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Pijnenburg, A. J. J., Honig, W. M. M., & Van Rossum, J. M. (1975) · Psychopharmacologia · doi:10.1007/bf00421062 · Cited by 330 · see citing works
A crystal-clear zebrafish for in vivo imaging
Antinucci, P., & Hindges, R. (2016) · Scientific Reports · doi:10.1038/srep29490 · Cited by 165 · see citing works
- Authors
- JOHNSON, G. A., BOUKMA, S. J., & KIM, E. G.
- Venue
- The Journal of Pharmacology and Experimental Therapeutics
- Publisher
- Elsevier BV
- Published
- 1970-01
- Volume
- 171
- Issue
- 1
- Pages
- 80-87
- ISSN
- 0022-3565 (ISSN-L)
- OpenAlex
- W4407042814
- Cited by
- 48
- References
- 0
- Citations by year
- 2021: 1 · 2020: 1 · 2016: 1
- FWCI
- 1.16
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Pharmacology and Experimental Therapeutics (publishedVersion)
- PubMed (publishedVersion)
- PubMed
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Receptor Mechanisms and Signaling
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Keywords
- dopamine beta-hydroxylase, enzyme inhibition, in vivo inhibition, thiourea derivatives, catecholamine synthesis
- MeSH terms
- Adrenal Glands, Adrenalectomy, Animals, Brain, Brain Chemistry, Carbon Isotopes, Catecholamines, Disulfiram, Dopamine, Hydrolases, Male, Metaraminol, Monoamine Oxidase Inhibitors, Myocardium, Norepinephrine, Species Specificity, Thiazoles, Thiourea, Time Factors, Tritium, Tyrosine, Dopamine Antagonists, Mice, Rats
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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