The DOI matches its Crossref record; 33 of the 35 references it cites were found in a registry or an index.
Prevalence of irritable bowel syndrome among university students
Abstract
Objective Relationships between presence of irritable bowel syndrome (IBS) and generalized anxiety disorder (GAD), chronic worry, neuroticism, anxiety sensitivity and anxiety about visceral sensations were examined among university students.Methods College student participants were administered self-report diagnostic measures of IBS and GAD, the Penn State Worry Questionnaire (PSWQ), the Neuroticism subscale of the Eysenck Personality Questionnaire, the Anxiety Sensitivity Index (ASI) and five additional items designed to measure visceral anxiety.Results The prevalence of IBS and its associated characteristics among students were similar to previous community survey studies, with the exception of lower symptom severity in the university sample. IBS was associated with a higher frequency of GAD and greater worry, neuroticism, anxiety sensitivity and visceral anxiety. Logistic regression analyses further showed that the measure of anxiety specific to visceral sensations was the strongest predictor of IBS diagnostic status.Conclusions While various aspects of anxiety appear related to IBS, specific anxiety about visceral sensations appears to be the most significant factor. Implications of the associations between anxiety-related variables, particularly anxiety about visceral sensations, are discussed.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Several studies have confirmed the impact of symptom-related fear and avoidance behaviors on symptom severity and quality of life in IBS [24,27-30].”
Citations
Cites
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
Development and validation of the Penn State Worry Questionnaire
Meyer, T. J., Miller, M. L., Metzger, R. L., & Borkovec, T. D. (1990) · Behaviour Research and Therapy · doi:10.1016/0005-7967(90)90135-6 · Cited by 5,099
Anxiety, sensitivity, anxiety frequency, and the prediction of fearfulness
Reiss, S., Peterson, R. A., Gursky, D. M., & McNally, R. J. (1986) · Behaviour Research and Therapy · doi:10.1016/0005-7967(86)90143-9 · Cited by 3,169
Functional bowel disorders and functional abdominal pain
Thompson, W. G., Longstreth, G. F., Drossman, D. A., Heaton, K. W., Irvine, E. J., & Müller-Lissner, S. A. (1999) · Gut · doi:10.1136/gut.45.2008.ii43 · Cited by 2,440
Drossman, D. A., Li, Z., Andruzzi, E., Temple, R. D., Talley, N. J., Grant Thompson, W., Whitehead, W. E., Janssens, J., Funch-Jensen, P., Corazziari, E., et al. (1993) · Digestive Diseases and Sciences · doi:10.1007/bf01303162 · Cited by 2,198
Clinical Handbook of Psychological Disorders: A Step-by-Step Treatment Manual
Barlow, D. H. (2001) · Cited by 782
Zinbarg, R. E., Barlow, D. H., & Brown, T. A. (1997) · Psychological Assessment · doi:10.1037/1040-3590.9.3.277 · Cited by 568
Newman, M. G., Zuellig, A. R., Kachin, K. E., Constantino, M. J., Przeworski, A., Erickson, T., & Cashman-McGrath, L. (2002) · Behavior Therapy · doi:10.1016/s0005-7894(02)80026-0 · Cited by 553
The Penn State Worry Questionnaire: Psychometric properties and associated characteristics.
Plaza, S. M., & Borkovec, T. D. (1994) · Cited by 523
Worrying: Perspectives on theory, assessment and treatment.
Davey, G. C. L., & Tallis, F. (1994) · Wiley eBooks · Cited by 451
Research works printed but not linked: 2
- Thompson, 1989, Irritable bowel syndrome: guidelines for the diagnosis, Gastroenterol Int, 2, 92
- Lydiard, 2001, Irritable bowel syndrome, anxiety, and depression: what are the links?, J Clin Psychiatry, 62, 38
Cited by
Sorted by citations
Items 101–171 of 171
Funaba, M., Kawanishi, H., Fujii, Y., Higami, K., Tomita, Y., Maruo, K., Sugawara, N., Oe, Y., 倉五月, Horikoshi, M., et al. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.673939 · Cited by 15
Calidad De Vida, Ansiedad y Depresión en Pacientes con Diagnóstico de Síndrome de Colon Irritable
Vinaccia, S., Fernández, H., Amador, O., Tamayo, R. E., Vásquez, A., Contreras, F., Tobón, S., & Sandín, B. (2005) · Terapia psicológica · Cited by 11
Lalouni, M., Olén, O., Bjureberg, J., Bonnert, M., Chalder, T., Hedman‐Lagerlöf, E., Rème, S. E., Serlachius, E., & Ljótsson, B. (2022) · Acta Paediatrica · doi:10.1111/apa.16403 · Cited by 9
Central Cholecystokinin Activity in Irritable Bowel Syndrome, Panic Disorder, and Healthy Controls
Koszycki, D., Torres, S., Swain, J. E., & Bradwejn, J. (2005) · Psychosomatic Medicine · doi:10.1097/01.psy.0000160465.79007.65 · Cited by 10
“Furthermore, PD and IBS patients have similar personality structures characterized by high neuroticism and harm avoidance and a cognitive style characterized by hypervigilance and hypersensitivity to internal stimuli (7,8).”
BackgroundStevens, E. S., Jendrusina, A. A., Sarapas, C., & Behar, E. (2014) · The Wiley Handbook of Anxiety Disorders · doi:10.1002/9781118775349.ch21 · Cited by 9
Baysoy, G., Baysoy, N. G., Kesicioğlu, A., Akın, D., Dündar, T., & Uyan, A. P. (2014) · The Turkish Journal of Pediatrics · doi:10.24953/turkjpediatr.2014.1431 · Cited by 9
Okami, Y., Nin, G., Harada, K., Wada, S., Tsuji, T., Okuyama, Y., Takakuwa, S., Kanazawa, M., Fukudo, S., & Higashi, A. (2013) · Open Journal of Gastroenterology · doi:10.4236/ojgas.2013.31009 · Cited by 8
“Therefore, it can be inferred that anxiety is a predictor of IBS diagnosis, and that psychological factors play an important role in the development of IBS [32-35].”
BackgroundIrritable bowel syndrome: associated features and the efficacy of psychosocial treatments
Olatunji, B. O., Tolin, D. F., & Lohr, J. M. (2004) · Applied and Preventive Psychology · doi:10.1016/j.appsy.2004.09.003 · Cited by 8
Grös, D. F., Antony, M. M., McCabe, R. E., & Lydiard, R. B. (2011) · Depression and Anxiety · doi:10.1002/da.20863 · Cited by 10
“The brief version of the BSQ was used to assess the Rome II criteria and general GI symptomatology.[16,32] The first four questions of the BSQ were used to assess the symptoms that were consistent with a diagnosis of IBS.”
MethodLamm, T. T., von Schrottenberg, V., Rauch, A., Bach, B., Pedersen, H. F., Rask, M. T., Ørnbøl, E., Wellnitz, K. B., & Frostholm, L. (2024) · Clinical Psychology Review · doi:10.1016/j.cpr.2024.102529 · Cited by 10
Treatment of school refusal in an adolescent with comorbid anxiety and chronic medical illness
Rohrig, S. N., & Puliafico, A. C. (2018) · Evidence-Based Practice in Child and Adolescent Mental Health · doi:10.1080/23794925.2018.1447855 · Cited by 7
Wright, C. D., Nelson, C. I., Brumbaugh, J. T., & McNeil, D. W. (2020) · International Journal of Behavioral Medicine · doi:10.1007/s12529-020-09912-6 · Cited by 8
Tamannaifar, M. R., & Akhavan-Hejazi, Z. S. (2013) · Fiyz̤. · Cited by 6
The Role of Psychosocial Factors in Functional Gastrointestinal Disorders
Lackner, J. M. (2014) · Frontiers of gastrointestinal research · doi:10.1159/000356785 · Cited by 7
Daniel Cisternas, C., Taft, T., Carlson, D. A., Glasinovic, E., Monrroy, H., Rey, P., Hani, A. C., Ardila‐Hani, A., Leguizamó, A. M., Bilder, C. R., et al. (2021) · Neurogastroenterology & Motility · doi:10.1111/nmo.14102 · Cited by 6
Schubach, A., Quigley, B. M., Lackner, J. M., & Gudleski, G. D. (2024) · Journal of Clinical Gastroenterology · doi:10.1097/mcg.0000000000001974 · Cited by 5
“25 In a meta-analysis of 27 studies comprising a comparison of 2293 patients with IBS to 4951 health controls, depression, and anxiety levels were signi fi cantly higher in patients with IBS than in controls by at least three-quarters of an SD. 26 Similar results were found in a meta-analysis of 10…”
Brain Processing of Gastrointestinal Sensory Signaling
Farmer, A. D., Ruffle, J. K., & Aziz, Q. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-809954-4.00016-5 · Cited by 6
Beath, A., Mcdonald, K., Osborn, T. C., & Jones, M. P. (2018) · Mindfulness · doi:10.1007/s12671-018-1019-8 · Cited by 5
Distress criterion influences prevalence rates of functional gastrointestinal disorders
Markert, C., Suarez-Hitz, K., Ehlert, U., & Nater, U. M. (2014) · BMC Gastroenterology · doi:10.1186/s12876-014-0215-9 · Cited by 5
“However, various studies have demonstrated that FGID are also prevalent in younger individuals [24,38-40].”
Personality and pain: Back to the four humours?
Tillisch, K. (2009) · Pain · doi:10.1016/j.pain.2009.04.019 · Cited by 5
“Neuroticism has often been associated with subjective reports of pain and bodily symptoms [3,9,11], though debate has existed as to whether this is primarily an effect of over-reporting.”
BackgroundLackner, J. M. (2024) · Pain · doi:10.1097/j.pain.0000000000003186 · Cited by 3
Abbott, D., & Lack, C. W. (2020) · Current Psychiatry Research and Reviews · doi:10.2174/2666082216666200220121648 · Cited by 3
Renna, M. E., O’Toole, M. S., Fresco, D. M., Heimberg, R. G., & Mennin, D. S. (2021) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2021.102403 · Cited by 4
Adamowicz, J. L., Sirotiak, Z., & Thomas, E. B. K. (2023) · Psychology Health & Medicine · doi:10.1080/13548506.2023.2216940 · Cited by 3
“…(Arnett, 2007), it has been documented that FSS can be present during young adulthood (Bakken et al., 2014; Chowdhury, 2012; Fischer et al., 2013; Hazlett-Stevens et al., 2003; Klastrup et al., 2022; Maxwell et al., 1997) and that minor increases in these complaints among adolescents have been…”
BackgroundResultInfluentialFraij, A., Shukry, A., Omira, A., Habbal, J., Ali, M. A., Jamal, N., Alawsi, S., & Talaat, I. M. (2024) · Cureus · doi:10.7759/cureus.71758 · Cited by 6
Alturkstani, A., Aljawi, M. S., Alhejaili, H. S., Almukarramah, M., Muhammad, A., & Arabia, S. (2013) · Cited by 3
Gastrointestinal mechanosensory function in health and disease
Page, A. J., & Li, H. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-812952-4.00013-1 · Cited by 3
Harris, K. M., Powell, M. L., Liwo, A., Vashi, B., Gray, R., Whitehead, A., Graham, C., Bibb, J. A., McLeod, C. M., Watts, S. A., et al. (2025) · AJPM Focus · doi:10.1016/j.focus.2025.100358 · Cited by 2
“33,34 However, the contribution of diet in combination with stress, depression, and anxiety to GI symptoms has not been extensively explored in college students.”
Hasan, A. B. M. N., Asaduzzaman, M., Mahfuj, M. N., Islam, R., Bhuyan, M. M. K., Basak, P., & Sharif, A. B. (2025) · PLOS Global Public Health · doi:10.1371/journal.pgph.0004670 · Cited by 4
“University students are particularly vulnerable due to unhealthy eating habits, excessive academic stress, and lifestyle choices such as smoking and alcohol consumption [3,8].”
Pharmacotherapy for gastric and intestinal cramping pain: current and emerging therapies
Mousavi, T., Sharifnia, M., Nikfar, S., & Abdollahi, M. R. (2023) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2023.2265830 · Cited by 2
“…mechanisms, including peripheral afferent neuron sensitization, DCLM, dorsal horn neuron sensitization, pain neurons hypersensitization affecting the spinal cord, as well as cognitive memories, causing misinterpretation of harmless sensation as a harmful condition like hypervigilance [20,21].”
BackgroundAlshehri, T. K., Alsharif, M. N. S., Asiri, L. A. A., Mukharrib, M. S., & Alzahrani, M. A. (2024) · Annals of African Medicine · doi:10.4103/aam.aam_14_19 · Cited by 3
“[21,22] On the other hand, university students in developing countries show a higher incidence rate of IBS, such as Pakistan (34%), Malaysia (15.8%), and Northern Nigeria (26.1%).”
InfluentialKoochaki-Ravandi, M., Monirpour, N., & Arj, A. (2015) · KAUMS Journal · Cited by 2
Ruffle, J. K., Frøkjær, J. B., & Farmer, A. D. (2017) · Springer eBooks · doi:10.1007/978-3-319-48046-6_13 · Cited by 2
IS THERE A RELATIONSHIP BETWEEN IRRITABLE BOWEL SYNDROME AND GENERALIZED ANXIETY DISORDER
Afridi, H. K., Ahmad, R., Sethi, M. R., & Irfan, M. (2017) · Journal of Postgraduate Medical Institute · Cited by 2
Ansiedad y Depresión en Pacientes con Trastornos Gastrointestinales Funcionales de Argentina
Ortega, I. S., Donatti, S., Cremades, C. F., & Garay, C. J. (2022) · Revista de PSICOLOGÍA DE LA SALUD · doi:10.21134/pssa.v10i1.814 · Cited by 4
What do repetitive thinking styles tell about hyperemesis gravidarum?
Yavuz, K. F., Ulusoy, S., Cebeci, E., & Şen, S. (2017) · Psychiatry and Clinical Psychopharmacology · doi:10.1080/24750573.2017.1407115 · Cited by 2
“specific to visceral sensations than their asymptomatic counterparts [50].”
BackgroundThe high prevalence and burden of irritable bowel syndrome among university students
Xiong, P., & Yang, W. (2023) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2023.05.011 · Cited by 1
Kamkar, A., Golzari, M., Farrokhi, N., Aghaee, S., & Fararouei, M. (2015) · DOAJ (DOAJ: Directory of Open Access Journals) · Cited by 1
Sieg, M., Mark, E. B., Drewes, A. M., & Vase, L. (2021) · Scandinavian Journal of Pain · doi:10.1515/sjpain-2021-0115 · Cited by 1
Spence, M. (2005) · ResearchSpace (University of Auckland) · Cited by 1
Functional problems : prevalence in secondary care and perceptions of doctors
Rajapakse, H. I. (2012) · Durham e-Theses (Durham University)
Shavikloo, M. I., Rahiminazhad, A., Sheikholeslami, H., Farahani, H., & Miroliaie, A. (2011) · GOVARESH
Controlled trial of hypnotherapy as a treatment for irritable bowel syndrome.
Phillips-Moore, J. (2009) · The Sydney eScholarship Repository (The University of Sydney)
Nelson, E. (2012) · Swinburne figshare (Swinburne University of Technology) · doi:10.25916/sut.26271883
Coen, S. J., Kano, M., Farmer, A. D., Kumari, V., Giampietro, V., Brammer, M. J., Williams, S., & Aziz, Q. (2011)
Gastro-intestinale klachten en stoornissen
van Tilburg, M. A. L., & Drossman, D. (2006) · Bohn Stafleu van Loghum eBooks · doi:10.1007/978-90-313-9254-4_11
Tomlinson, R. C. (2014) · The Atrium (University of Guelph)
Roy, N. M. (2020) · DigitalCommons (California Polytechnic State University)
Irritable bowel syndrome - a disorder of gut-brain interaction
Midenfjord, I. (2021) · Gothenburg University Publications Electronic Archive (Gothenburg University)
Alemany, S., Artigas, M. S., Cabana‐Domínguez, J., Fakhreddine, D., Llonga, N., Vilar‐Ribó, L., Rodríguez‐Urrutia, A., Palacio, J., González-Castro, A. M., Lobo, B., et al. (2023) · medRxiv · doi:10.1101/2023.01.30.23285080
Neto, I. J. F. C., Silva, A. D. L., Tajiri, R. C. D. M., Theis, C., Schelle, G., Pinto, R. A., Nishiyama, V. K. G., & Robles, L. (2023) · Journal of Coloproctology · doi:10.1055/s-0043-1764193
“24,41 Fond et al. 42 presented in their meta-analysis collecting 10 studies that people who suffered from CC presented considerable higher levels of anxiety than nonconstipated individuals (95%CI: 47 – 69%; p < 0.01).”
BackgroundInfluentialPsihološke odrednice sindroma suhog oka
Toth, M. (2023) · doi:10.17234/diss.2023.8795
Wu, H., Liu, Q., Liu, J., & Liu, M. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1420970 · Cited by 1
Learned Symptom-Specific Fear Toward a Visceral Sensation and Its Impact on Perceptual Habituation
Pattyn, L., Zaman, J., van de Pavert, I., Jelinčić, V., von Leupoldt, A., Oudenhove, L. V., & Diest, I. V. (2024) · Psychosomatic Medicine · doi:10.1097/psy.0000000000001345
“Symptom-specific fear is known to contribute to overall symptom burden to a greater extent than generic anxiety or negative affect (2 – 5).”
Engel, F., Banzhaf, P., & Berens, S. (2024) · Trauma und Gewalt · doi:10.21706/tg-18-4-340
Störungen der Darm-Hirn-Achse (gut-brain axis)
Elsenbruch, S. (2024) · Springer eBooks · doi:10.1007/978-3-662-68436-8_4
Bakhshaie, J., Smit, T., Bradford, A. M., Lackner, J. M., & Zvolensky, M. J. (2025) · Journal of Health Psychology · doi:10.1177/13591053251333950
“For instance, higher levels of GI-specific anxiety are associated with greater IBS symptom severity and poorer quality of life among persons with IBS (Hazlett-Stevens et al., 2003; Lackner et al., 2014).”
Zvolensky, M. J., Smit, T., Wein, P. Y., Bakhshaie, J., Redmond, B. Y., Garey, L., Thai, J. M., & Lackner, J. M. (2025) · Journal of Behavioral Medicine · doi:10.1007/s10865-025-00576-9
“Higher levels of GI-specific anxi - ety are linked to more severe IBS symptoms, increased pain, poorer coping with interoceptive sensations, and reduced quality of life (Hazlett-Stevens et al., 2003; Labus et al., 2004, 2005, 2007; Ljótsson et al., 2013).”
Attentional Biases in Irritable Bowel Syndrome Patients
Tkalčić, M., Tončić, M., Pletikosić, S., Perić, R. T., & Hauser, G. (2025) · Journal of Clinical Gastroenterology · doi:10.1097/mcg.0000000000002200
Alshehri, W. M., Elhady, H. M., Alharbi, A. A., Alshehri, W. A., Albalawi, A., Alkhrissi, N. M., Almutairi, H. A., & Albalawi, A. (2025) · Cureus · doi:10.7759/cureus.88138
Exploring the Link Between Irritable Bowel Syndrome and Chronic Diseases: A Narrative Overview
Reddy, S., & Veluri, S. C. (2025) · Academic Medicine & Surgery · doi:10.62186/001c.143576
Überblick und Zusammenfassung Abschnitt 3
Lederman, E. (2007) · Elsevier eBooks · doi:10.1016/b978-343757940-0.10027-6
Alemany, S., Artigas, M. S., Domínguez, J. C., Fakhreddine, D., Llonga, N., Vilar‐Ribó, L., Rodríguez‐Urrutia, A., Palacio, J., González-Castro, A. M., Lobo, B., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26584023
Alemany, S., Artigas, M. S., Domínguez, J. C., Fakhreddine, D., Llonga, N., Vilar‐Ribó, L., Rodríguez‐Urrutia, A., Palacio, J., González-Castro, A. M., Lobo, B., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26584020
Alemany, S., Artigas, M. S., Domínguez, J. C., Fakhreddine, D., Llonga, N., Vilar‐Ribó, L., Rodríguez‐Urrutia, A., Palacio, J., González-Castro, A. M., Lobo, B., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26584017
Predictors of Change in Health Care Use After Marital and Family Therapy
Payne, S. H. (2006) · ScholarsArchive (Brigham Young University)
Metadata
- Authors
- Hazlett-Stevens, H., Craske, M. G., Mayer, E. A., Chang, L., & Naliboff, B. D.
- Affiliations
- University of California, Los Angeles (US)
- Venue
- Journal of Psychosomatic Research
- Publisher
- Elsevier BV
- Published
- 2003-12
- Volume
- 55
- Issue
- 6
- Pages
- 501-505
- ISSN
- 0022-3999 (ISSN-L)
- OpenAlex
- W2037171358
- Cited by
- 170
- References
- 35
- Citations by year
- 2025: 8 · 2024: 11 · 2023: 8 · 2022: 6 · 2021: 8 · 2020: 6 · 2019: 2 · 2018: 12 · 2017: 8 · 2016: 7 · 2015: 3 · 2014: 15 · 2013: 10 · 2012: 9
- FWCI
- 4.46
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Psychosomatic Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- irritable bowel syndrome, prevalence, university students, generalized anxiety disorder, chronic worry, neuroticism, anxiety sensitivity, symptom severity
- MeSH terms
- Adolescent, Adult, Anxiety Disorders, Arousal, Attitude to Health, California, Cross-Sectional Studies, Female, Humans, Male, Personality Inventory, Psychophysiologic Disorders, Students, Abdominal Pain, Irritable Bowel Syndrome
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review