The DOI matches its Crossref record; 159 of the 173 references it cites were found in a registry or an index.
Autonomic balance revisited: Panic anxiety and heart rate variability
Abstract
The analysis of heart rate variability (HRV) is becoming widely used in clinical research to provide a window into autonomic control of HR. This technique has been valuable in elucidating the autonomic underpinnings of panic disorder (PD), a condition that is marked by reports of heart palpitations. A body of research has emerged that implicates a relative reduction in HRV and cardiac vagal tone in PD, as indicated by various HRV measures. These data are consistent with the cardiac symptoms of panic attacks, as well as with developmental evidence that links high vagal tone with enhanced attention, effective emotion regulation, and organismic responsivity. Implications of these findings for nosology and pathophysiology are discussed. Reports of reduced HRV in PD contrast with portrayals of excess autonomic lability in anxiety. This contradiction is addressed in the context of traditional homeostatic models versus a systems perspective that views physiologic variability as essential to overall stability.
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“the vagus nerve innervates a number of end organs that are involved in emotion and communication (i.e., larynx, facial muscles, Porges, 1995), and the vagal input to the heart can be quickly withdrawn to allow rapid mobilization of the body to meet a variety of environmental and metabolic demands; these include physical exercise, coping with negative emotion (e.g., Beauchaine, 2001; Friedman & Tha”
From Psychological flexibility as a fundamental aspect of health (2010) · cites this paper as Friedman & Thayer, 1998
In the citing paper
“Processes that may contribute to this over-responsivity include increased threat perception, increased and misinterpreted perception of bodily sensations [34], or decreased inhibition of the fear response.”
From Functional autonomic nervous system profile in children with autism spectrum disorder (2014) · cites this paper as [34]
In the citing paper
“Highlighting the role of the physiological dimension, chronically elevated HR has been reported in anxiety disorders [32-34].”
From Functional autonomic nervous system profile in children with autism spectrum disorder (2014) · cites this paper as [34]
In the citing paper
“At this level, hyperarousal may be associated with over-responsivity of networks involved in perception, processing, and responding to emotional stimuli [34].”
From Functional autonomic nervous system profile in children with autism spectrum disorder (2014) · cites this paper as [34]
In the citing paper
“Reduced HRV is a clinically relevant feature of stress-related disorders including anxiety, depression, and epilepsy (Carney et al., 1995b; Friedman and Thayer, 1998; Brown and Gerbarg, 2005; Mativo et al., 2010).”
From Hypothesis: Pulmonary Afferent Activity Patterns During Slow, Deep Breathing Contribute to the Neural Induction of Physiological Relaxation (2019) · cites this paper as Friedman and Thayer, 1998
Citations
Cites
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
James, W. (1891) · Personality Culture Society · doi:10.1037/11059-000 · Cited by 25,876
The Standard Edition of the Complete Psychological Works of Sigmund Freud
Freud, S. (1953) · Cited by 17,730
Diagnostic and Statistical Manual of Mental Disorders
&NA; (1988) · Alzheimer Disease & Associated Disorders · doi:10.1097/00002093-198802020-00022 · Cited by 12,603
Cognitive, social, and physiological determinants of emotional state.
Schachter, S., & Singer, J. (1962) · Psychological Review · doi:10.1037/h0046234 · Cited by 6,223
Cardiovascular neural regulation explored in the frequency domain.
Malliani, A., Pagani, M., Lombardi, F., & Cerutti, S. (1991) · Circulation · doi:10.1161/01.cir.84.2.482 · Cited by 3,569
Prigogine, I., Stengers, I., & Pagels, H. R. (1984) · Cited by 2,468
Order out of chaos : man's new dialogue with nature.
Prigogine, I., & Stengers, I. (1984) · Cited by 2,391
Bodily Changes in Pain, Hunger, Fear, and Rage.
Washburn, M. F., & Cannon, W. B. (1917) · The Journal of Philosophy Psychology and Scientific Methods · doi:10.2307/2013624 · Cited by 1,912
Personality and Individual Differences
Eysenck, H. J., & Eysenck, M. W. (1985) · doi:10.1007/978-1-4613-2413-3 · Cited by 1,893
Research works printed but not linked: 7
- Miyawaki, 1991, Autonomic nervous system tests in psychiatry: implications and potential uses of heart rate variability, Integr Psychiatry, 7, 21
- Margraf, 1990, Ambulatory psychophysiological monitoring of panic attacks, J Psychophysiol, 4, 321
- Bronis, 1983, Heart rate variability and autonomous system: some possible relations, Automedica, 4, 223
- Friedman BH, Thayer JT. Anxiety and autonomic flexibility: a cardiovascular approach. Biol Psychol (in press).
- Marks, 1982, Are there anticompulsive or antiphobic drugs?, Psychopharmacol Bull, 18, 70
- Coryell, 1986, Mortality among patients with anxiety disorders, Am J Psychiatry, 39, 508
- Friedman, 1993, Heart rate variability in generalized anxiety disorder, Psychophysiology, 30, S28
Cited by
Sorted by citations
Items 401–500 of 615
Yang, X., Spangler, D. P., Thayer, J. F., & Friedman, B. H. (2021) · Psychophysiology · doi:10.1111/psyp.13833 · Cited by 10
Self-citationBiofeedback and Anxiety Disorders: A Critical Review of EMG, EEG, and HRV Feedback
Tabachnick, L. (2015) · Cited by 10
Biobehavioral assessment of the anxiety disorders: Current progress and future directions
Abbott, D., Shirali, Y., Haws, J. K., & Lack, C. W. (2017) · World Journal of Psychiatry · doi:10.5498/wjp.v7.i3.133 · Cited by 12
Wekenborg, M., Hill, L. K., Miller, R. E., Tobias Stalder, A., Thayer, J. F., Penz, M. S., & Kirschbaum, C. (2018) · Stress · doi:10.1080/10253890.2018.1479393 · Cited by 10
“…also showed that resting-state HRV mirrored this effect, replicating previous findings that low levels of vagally mediated HRV are associated with a rigid appraisal of environmental demands (Friedman & Thayer, 1998; Melzig, Weike, Hamm, & Thayer, 2009; Ruiz-Padial, Sollers, Vila, & Thayer, 2003).”
ResultSelf-citationCan Illness Perceptions Predict Lower Heart Rate Variability following Acute Myocardial Infarction?
Princip, M., Scholz, M., Meister‐Langraf, R. E., Barth, J., Schnyder, U., Znoj, H., Schmid, J., Thayer, J. F., & von Känel, R. (2016) · Frontiers in Psychology · doi:10.3389/fpsyg.2016.01801 · Cited by 10
“…1, Rebecca E. Meister-Langraf 1, 2, 4, Jürgen Barth 5, Ulrich Schnyder 6, Hansjörg Znoj 7, Jean-Paul Schmid 8, Julian F. Thayer 9 and Roland von Känel 1, 2, 10 1Department of Neurology, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland, 2 Psychosomatic Research…”
BackgroundSelf-citationConstant, E., Leuchtmann, L., Christophe, V., Bodenmann, G., Gabrielli, F., Ott, L., & Nandrino, J. (2020) · Scandinavian Journal of Psychology · doi:10.1111/sjop.12641 · Cited by 9
Gordon, I., Horesh, D., Milstein, N., Tomashin, A., Mayo, O., & Korisky, A. (2021) · Psychophysiology · doi:10.1111/psyp.13910 · Cited by 10
“The | 3 of 10GORDON et al. neurovisceral integration model (Friedman & Thayer, 1998; Thayer & Lane, 2000) considers resting RSA as a marker for neural feedback mechanisms needed for the integration between the ANS and the central nervous system, termed as “autonomic nervous system integration.””
BackgroundChronic fatigue in adolescence—autonomic dysregulation and mental health: an exploratory study
Gjone, H., & Wyller, V. B. (2009) · Acta Paediatrica · doi:10.1111/j.1651-2227.2009.01323.x · Cited by 9
“indicate reduced vagal and increased sympathetic activity in patients with panic disorder (15).”
BackgroundDiminished Vagal and/or Increased Sympathetic Activity in Post-Traumatic Stress Disorder
Agorastos, A., Kellner, M., Baker, D. G., & Stiedl, O. (2015) · Comprehensive Guide to Post-Traumatic Stress Disorder · doi:10.1007/978-3-319-08613-2_30-1 · Cited by 9
Rossignol, M., Philippot, P., & Vögele, C. (2016) · Santé mentale au Québec · doi:10.7202/1036971ar · Cited by 9
“Ces résultats sont consistants avec le modèle d’un manque de flexibilité autonomique dans les troubles anxieux (Friedman, 2007 ; Friedman & Thayer, 1998a, 1998b ; Thayer & Friedman, 1997).”
BackgroundMethods for Studying the Psychophysiology of Emotion.
Santerre, C., & Allen, J. J. B. (2007) · American Psychological Association eBooks · doi:10.1037/11562-003 · Cited by 10
Gustafson, K. M., & Popescu, E. A. (2016) · Springer eBooks · doi:10.1007/978-3-319-22023-9_23 · Cited by 9
Shioiri, T., Kojima, M., Hosoki, T., Kitamura, H., Tanaka, A., Bando, T., & Someya, T. (2004) · Journal of Affective Disorders · doi:10.1016/j.jad.2004.03.008 · Cited by 10
“, 1996), was reduced by a low vagal tone (Friedman and Thayer, 1998).”
BackgroundResultGulewitsch, M. D., Jusyte, A., Mazurak, N., Weimer, K., & Schönenberg, M. (2017) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2017.05.008 · Cited by 10
Ultra Low-Power Drowsiness Detection System with BioWolf
Kartsch, V., Benatti, S., Guermandi, M., Montagna, F., & Luca Benini, C. (2019) · International IEEE/EMBS Conference on Neural Engineering · doi:10.1109/ner.2019.8717070 · Cited by 8
“However, inter-subject variability suggests that physiological analysis by itself is not sufficient to provide a strong enough generalization the drowsiness detection algorithms [7], and many proposed solutions rely on supervised and user-dependent approaches [8].”
BackgroundXing, W., Lu, W. D., & Wang, Z. (2019) · Stress and Health · doi:10.1002/smi.2885 · Cited by 8
Reed, A. C., Lee, J., Green, M. F., Hamilton, H., Miller, G. A., Subotnik, K. L., Ventura, J., Nuechterlein, K. H., & Yee, C. M. (2020) · Schizophrenia Research · doi:10.1016/j.schres.2019.12.040 · Cited by 8
Nelson, K. L., Lu, S., Oken, T., Lehrer, P. M., & Feldman, J. M. (2020) · Applied Psychophysiology and Biofeedback · doi:10.1007/s10484-020-09454-3 · Cited by 10
Neuroticism, Extraversion and Stress: Physiological Correlates
Brouwer, A.-M., van Schaik, M., van Erp, J. B. F., & Korteling, H. (2013) · International Conference on Affective Computing and Intelligent Interaction and workshops · doi:10.1109/acii.2013.77 · Cited by 8
“Consistent with this, anxious, depressed and stressed individuals have been reported to have low heart rate variability [10] [42] [3] [17] [11].”
BackgroundThe SNAPSHOT study protocol: SNAcking, Physical activity, Self-regulation, and Heart rate Over Time
McMinn, D., & Allan, J. (2014) · BMC Public Health · doi:10.1186/1471-2458-14-1006 · Cited by 8
“Tonic heart rate variability (HRV) may be a physiological indicator of the current level of cognitive, emotional, and behaviour regulation [54,55].”
BackgroundColes, J., Vögele, C., Hilbert, A., & Tuschen‐Caffier, B. (2005) · Zeitschrift für Klinische Psychologie und Psychotherapie · doi:10.1026/1616-3443.34.2.95 · Cited by 8
Sluiter, J. K., Guijt, A. M., & Frings‐Dresen, M. H. W. (2008) · International Archives of Occupational and Environmental Health · doi:10.1007/s00420-008-0391-4 · Cited by 7
Sympathetic reactivity in agoraphobic patients with and without personality disorders
Ekeberg, Ø., Hedley, L. M., Einvik, G., Rostrup, M., & Hoffart, A. (2003) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(02)00439-7 · Cited by 8
“The reduction in heart rate variability and cardiac vagal tone in panic disorder [29] can be reversed by use of the serotonin reuptake inhibitor paroxetine [30].”
BackgroundRadanliev, P. (2025) · Research in Dance Education · doi:10.1080/14647893.2025.2486256 · Cited by 7
Heart Rate Variability (HRV) of Male Subjects Related to Oral Reports of Affective Pictures
Rantanen, A. P., Siipo, A., Seppänen, T., Väyrynen, E., Lehtihalmes, M., & Laukka, S. J. (2013) · Procedia - Social and Behavioral Sciences · doi:10.1016/j.sbspro.2013.06.501 · Cited by 7
Effect of attention demand on upper trapezius muscle activity – A moderated mediation model
Wixted, F., & O'Sullivan, L. W. (2018) · International Journal of Industrial Ergonomics · doi:10.1016/j.ergon.2018.03.001 · Cited by 7
Delgadillo, D. R., Boparai, S., Pressman, S. D., Goldstein, A., Bureau, J., Schmiedel, S., Backer, M., Broekman, B. F. P., Tan, K. H., Chong, Y. S., et al. (2021) · Developmental Psychobiology · doi:10.1002/dev.22082 · Cited by 7
Synthesis of dinucleoside tetraphosphates in transfected cells by a firefly luciferase reporter gene
Murphy, G. A., & McLennan, A. G. (2004) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-003-3420-1 · Cited by 7
Olsson, E. M. G. (2010) · KTH Publication Database DiVA (KTH Royal Institute of Technology) · Cited by 7
Alessandri, G., Filosa, L., Eisenberg, N., & Ottaviani, C. (2023) · Psychosomatic Medicine · doi:10.1097/psy.0000000000001191 · Cited by 6
“In this regard, valuable proxies for emotion regulation ability (20), as well as for psychological flexibility (21), are resting or tonic vagally mediated heart rate (HR) variability (HRV) and respiratory sinus arrhythmia (RSA; i.”
BackgroundDai, F., Costa, E. D., Giordano, A., Heinzl, E. U. L., Giongo, P., Pagnozzi, G., Cannas, S., Minozzi, G., & Minero, M. (2022) · Research in Veterinary Science · doi:10.1016/j.rvsc.2022.01.017 · Cited by 6
Viti, A., Panconi, G., Guarducci, S., Garfagnini, S., Mondonico, M., Bravi, R., & Minciacchi, D. (2023) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20053934 · Cited by 6
Sanders, W., & Abaied, J. L. (2015) · Motivation and Emotion · doi:10.1007/s11031-015-9470-5 · Cited by 7
“iety (i.e., worry and panic; Brosschot et al. 2007; Friedman and Thayer 1998) and depression (Chang et al.”
BackgroundThe Connection between Skilled Counseling and Client's Heart Rate Variability
Kiema-Junes, H. K., Rantanen, A. P., Laukka, S. J., Siipo, A., & Soini, H. (2014) · Procedia - Social and Behavioral Sciences · doi:10.1016/j.sbspro.2014.12.452 · Cited by 6
O'Brien, K. M., Afzal, K., & Tronick, E. (2013) · Springer eBooks · doi:10.1007/978-1-4614-7141-7_13 · Cited by 8
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Tonnsen, B. L., & Roberts, J. E. (2016) · International review of research in developmental disabilities · doi:10.1016/bs.irrdd.2016.07.003 · Cited by 6
Condy, E. E., Factor, R. S., Swain, D. M., Strege, M. V., & Scarpa, A. (2019) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-019-04198-4 · Cited by 7
Rousseau, S., Kritzman, L., Frenkel, T. I., Levit‐Binnun, N., & Golland, Y. (2019) · Developmental Psychobiology · doi:10.1002/dev.21939 · Cited by 6
Real-Time Psychophysiological and Writing Correlates of Expressive Writing
Jacques, T., Alves, R. A., Fadaei, S., & Barbosa, F. (2020) · Experimental Psychology (formerly Zeitschrift für Experimentelle Psychologie) · doi:10.1027/1618-3169/a000495 · Cited by 6
Implications of Corporate Yoga: A Review
Bhandari, R. B., Churna, B., Acharya, B., Pandya, P., Singh, K., Vinod, K., & Ganesh, D. (2012) · InTech eBooks · doi:10.5772/36657 · Cited by 7
“Furthermore, they emphasized that slow breathing with prolonged expiration was shown to reduce psychological and physiological arousal, anxiety, panic disorder, depression, IBS, early Alzheimer’s disease and obesity (Friedman & Thayer 1998; Haug et al. 1994).”
BackgroundSteinerová, K., Krause, A., Parker, S., & Seddon, Y. M. (2025) · Frontiers in Veterinary Science · doi:10.3389/fvets.2025.1518153 · Cited by 5
Cribbet, M. R., Thayer, J. F., Jarczok, M. N., & Fischer, J. E. (2024) · Psychosomatic Medicine · doi:10.1097/psy.0000000000001302 · Cited by 5
Self-citationLiou, H., Chao, Y.-F. C., Kuo, T. B. J., & Chen, H. I. (2008) · PubMed · Cited by 5
A Pilot Study of Cardiovascular Reactivity in Children With Autism Spectrum Disorder
Amoss, R. T., Leong, T. L., Evans, A. N., Ousley, O., Herrington, J. D., Lecavalier, L., Goodwin, M. S., Hofmann, S. G., & Scahill, L. D. (2020) · Seminars in Pediatric Neurology · doi:10.1016/j.spen.2020.100807 · Cited by 7
Assessment of a dive incident using heart rate variability
Zenske, A., Koch, A., Kähler, W., Oellrich, K., Pepper, C., Muth, T., & Schipke, J. D. (2020) · Diving and Hyperbaric Medicine Journal · doi:10.28920/dhm50.2.157-163 · Cited by 5
Diminished Vagal and/or Increased Sympathetic Activity in Post-Traumatic Stress Disorder
Agorastos, A., Kellner, M. B., Baker, D. G., & Stiedl, O. (2016) · Springer eBooks · doi:10.1007/978-3-319-08359-9_30 · Cited by 5
Effet de l’entraînement aérobie sur la variabilité de la fréquence cardiaque au repos
Gamelin, F.-X., Berthoin, S., & Bosquet, L. (2008) · Science & Sports · doi:10.1016/j.scispo.2008.10.004 · Cited by 5
Physiological and emotional stress reactions : the effects of temperament and exhaustion
Heponiemi, T. (2004) · Työväentutkimus Vuosikirja · Cited by 5
Predicting Calmness, Anxiety, and Depression using Wearable SensorsPreprint
Borthakur, R., Sharma, N. L., & Pattanaik, P. R. (2022) · Research Square · doi:10.21203/rs.3.rs-1273712/v1 · Cited by 5
Thayer, J. F., Hansen, A. L., & Johnsen, B. H. (2022) · Springer eBooks · doi:10.1007/978-0-387-85960-6_38 · Cited by 4
Self-citationMaharjan, A., Khwaounjoo, P., Peng, M., & Çakmak, Y. Ö. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.950282 · Cited by 4
He, H., Gao, H., Xie, X., Wang, Y., & Zhang, R. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.11.039 · Cited by 4
Preliminary evidence for altered brain-heart coherence during anxiogenic movies
Kirk, P. A., & Robinson, O. J. (2024) · Imaging Neuroscience · doi:10.1162/imag_a_00156 · Cited by 5
“…and activity across branches of the autonomic nervous system (often summarized as increased sympathetic activation and/or parasympathetic withdrawal), using proxies such as heart rate, heart rate variability, and skin conductance ( Friedman & Thayer, 1998; Hodges & Spielberger, 1966; Lader, 1967).”
MethodGarcía, J. P. F., & Villafaina, S. (2024) · Behavioral Sciences · doi:10.3390/bs14111044 · Cited by 4
“One such network is the anterior executive region, which is associated with processes of response, reorganization, and selection and serves as a source of psychophysiological control in attention and emotions [18].”
Vagal heart rate variability during rapid eye movement sleep reduces negative memory bias
Morehouse, A. B., Simon, K. C. N. S., Chen, P., & Mednick, S. C. (2025) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2025.1513655 · Cited by 4
“…how effectively an individual can activate the vagal nervous system to slow down the heart rate in response to increased sympathetic arousal from environmental stressors, or effectively transition from a heightened state to a more relaxed state (Friedman and Thayer, 1998; Thayer and Lane, 2000).”
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Nayak, S., Srivastava, U., Tibarewala, D. N., Thakur, G., Mohapatra, B., & Pal, K. (2017) · Advances in medical technologies and clinical practice book series · doi:10.4018/978-1-5225-0536-5.ch012 · Cited by 5
Measuring Stress, Anxiety, and Depression in PTSD Sufferers Using Micro-Movements from Video
Holt, R. A., Jones, S., & Washington, G. J. (2016) · IEEE International Conference on Healthcare Informatics (ICHI) · doi:10.1109/ichi.2016.88 · Cited by 4
“Feelings of sadness, anxiety, and depression may be identified in humans through decreased heart rate and/or heart rate variability (HRV) [2][3].”
BackgroundKeen, L., Tan, A. Y., & Abbate, A. (2020) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2020.06.013 · Cited by 4
“Moreover, sympathetic activation may be related to the novelty of the laboratory setting or to preparation for engagement in the task (Friedman and Thayer, 1998).”
BackgroundPhysiological Measures of Welfare
Capitanio, J. P., Vandeleest, J. J., & Hannibal, D. L. (2023) · Springer eBooks · doi:10.1007/978-3-030-82708-3_10 · Cited by 6
Idiodynamics Vis-à-vis Psychophysiology: An Idiodynamic Portrayal of Cardiovascular Reactivity
Friedman, B. H. (2003) · International Journal of Applied Psychoanalytic Studies · doi:10.1023/a:1026019614831 · Cited by 4
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BackgroundInfluentialSelf-citationThe influence of trait anxiety on the elevation of arterial pressure induced by l-NAME in rats
Garcez, F. B., Carvalho, F. U. R., Soares, A. P. D. S., Goes, T. C., dos Santos, M. R. V., & Teixeira-Silva, F. (2014) · Neuroscience Letters · doi:10.1016/j.neulet.2014.09.011 · Cited by 4
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Chen, Y., Oyama-Higa, M., & Pham, T. D. (2014) · Communications in computer and information science · doi:10.1007/978-3-642-54121-6_3 · Cited by 4
Utsey, S. O., Abrams, J. A., Hess, D. W., & McKinley, W. O. (2014) · Journal of Black Psychology · doi:10.1177/0095798414532186 · Cited by 4
Mapping the Neurophysiological Link Between Voice and Autonomic Function: A Scoping Review
Morales-Luque, C., Carrillo-Franco, L., López-González, M. V., González-García, M., & Dawid-Milner, M. S. (2025) · Biology · doi:10.3390/biology14101382 · Cited by 3
“This pattern is consistent with the view that cognitive–evaluative stres-Biology sors trigger a coordinated activation of the HPA axis and the ANS and with evidence that individual differences in autonomic flexibility shape variability in stress reactivity [46,47].”
The effect of COVID-19 infection on heart rate variability: A cross-sectional study
Huyut, M. A., Levent, F., Tütüncü, A., Özmen, G., Ormancı, D., & Vatansever, F. (2022) · International Journal of the Cardiovascular Academy · doi:10.4103/ijca.ijca_9_22 · Cited by 3
“[5‑8] Aging and psychiatric disorders can lead to reduced HRV, and gender variations have also been shown in HRV. [9,10] The severe acute respiratory syndrome coronavirus‑2 (SARS‑CoV‑2), which is the agent virus of coronavirus disease‑2019 (COVID‑19), has spread worldwide in the past 2 years…”
Chen, S., Pan, W., Gau, M., Hsu, T.-C., & Shen, S.-C. (2024) · Applied Psychophysiology and Biofeedback · doi:10.1007/s10484-024-09656-z · Cited by 5
Haemodynamic Patterns in Reflex Syncope: Insights from Head-Up Tilt Tests in Adults and Children
Laranjo, S. M., Fonseca, H., Félix, A. C., Gourine, A. V., Pinto, F. F., Oliveira, M., & Rocha, I. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14061874 · Cited by 3
“Future studies incorporating validated anxiety scales, heart rate variability (HRV) indices, and stress biomarkers could provide further insight into how psychological factors modulate cardiovascular responses in paediatric syncope [26–28].”
Panik Bozukluğu Hastalarında Uykuda Kalp Hızı Değişkenliği
Yetki̇n, S., Erdamar, A., Yokuşoğlu, M., Özgen, F., & Aydın, H. (2014) · Journal of Turkish Sleep Medicine · doi:10.4274/jtsm.05 · Cited by 3
Investigating Mindsets and Motivation through Eye Tracking and Other Physiological Measures
Zentall, S. R., & Junglen, A. (2017) · Advances in educational technologies and instructional design book series · doi:10.4018/978-1-5225-1005-5.ch003 · Cited by 2
Measuring the human psychophysiological conditions without contact
Scalise, L., Casacanditella, L., & Cosoli, G. (2017) · Journal of Physics Conference Series · doi:10.1088/1742-6596/882/1/012016 · Cited by 3
“The analysis of HRV allows to characterize the health and psychophysiological conditions of a subject, which cause changes in the balance between sympathetic and parasympathetic systems (18,19).”
BackgroundIdentifying Patterns in Complex Field Data
White, A. J., Kleinböhl, D., Lang�, T., Hamm, A. O., Gerlach, A. L., & Alpers, G. W. (2017) · Zeitschrift für Psychologie · doi:10.1027/2151-2604/a000310 · Cited by 3
“Moreover, compared to other symptoms, cardiovascular disturbances are central to panic (Cohen et al., 2000; Friedman & Thayer, 1998) and greatest during situational exposure (Alpers, Wilhelm, & Roth, 2005).”
BackgroundRespiratory Sinus Arrhythmia During Sleep and Waking
Stoakley, E. M., Mathewson, K. J., Schmidt, L. A., & Côté, K. A. (2017) · Journal of Psychophysiology · doi:10.1027/0269-8803/a000200 · Cited by 5
Sharing Video Emotional Information in the Web
Oliveira, E., Chambel, T., & Ribeiro, N. M. (2013) · International Journal of Web Portals · doi:10.4018/ijwp.2013070102 · Cited by 3
“For example heart rate has been used to differentiate positive from negative emotions, suggesting that several emotions can be predicted and defined by the analysis of patterns of cardio (heart-rate) and respiratory activity (Friedman & Thayer, 1998; Rao & Vikram, 2001).”
BackgroundNeurovisceral integration in emotion and health
Thayer, J. F., & Ruiz‐Padial, E. (2002) · International Congress Series · doi:10.1016/s0531-5131(02)00648-9 · Cited by 3
Self-citationHeart rate variability for assessing stress in cows.
Antón, M. M., & Solcan, G. (2012) · Cited by 3
Sex and Gender Differences in Psychosocial Risk Factors for Ischemic Heart Disease
Mommersteeg, P. M. C., Widdershoven, J. W. M. G., & Kop, W. J. (2017) · Springer eBooks · doi:10.1007/978-3-319-54960-6_13 · Cited by 3
Evaluation of Heart Rate Variability in Drug Free Panic Disorder Patients
Durdu, G. S., Kayıkçıoğlu, M., Pırıldar, Ş., & Köse, T. (2017) · Nöro Psikiyatri Arşivi · doi:10.5152/npa.2017.19429 · Cited by 3
“In the majority of the studies regarding panic disorder, short-time provocation (Na lactate infusion, postural change, cold, various pharmacological drug infusions) or resting records were reviewed (15,16,17,18,19,20).”
BackgroundPsychosomatik der Herzinsuffizienz: Alles nur Depression?
Herrmann‐Lingen, C. (2011) · Herz · Cited by 3
Fish, M. T. (2011) · The Scholarship East Carolina University's Institutional Repository (East Carolina University) · Cited by 3
Benoit, K. E. (2013) · VTechWorks (Virginia Tech) · Cited by 3
Rose, K. A., Kizhakkeveettil, A., Kadar, G. E., & Losack, M. (2016) · Journal of Chiropractic Medicine · doi:10.1016/j.jcm.2016.09.004 · Cited by 2
Petrowski, K., Wendt, K., Wichmann, S., & Siepmann, M. (2017) · Journal of Depression And Therapy · doi:10.14302/issn.2476-1710.jdt-16-1332 · Cited by 1
“In clinical psychological research, decreased HRV parameters were associated with negative affectivity, especially with anxiety [22] and anger [23] and with mental disorders such as depression [24-32] and anxiety disorders [22,33].”
BackgroundYang, X., Gazzanigo, M. J., Fang, F., & House, S. (2025) · Physiological Reports · doi:10.14814/phy2.70466 · Cited by 3
Hu, D. D. (2011) · OhioLink ETD Center (Ohio Library and Information Network) · Cited by 2
PhysioDataBase: Free online repository for heart rate variability studies
Mendez-Candeias, B., Cuesta, P., Rodrı́guez-Liñares, L., Lado, M. J., & Mondelo, V. (2018) · Iberian Conference on Information Systems and Technologies (CISTI) · doi:10.23919/cisti.2018.8399419 · Cited by 2
“It has been successfully used for the last decades not only in the detection and diagnosis or cardiac diseases [4], [5], [6], but also in other research areas, such as sleep apnea [7], chronic obstructive pulmonary disease (COPD) [8], diabetes [9], panic disorder [10] or psychopathy [11].”
MethodVomit Comet Physiology: Autonomic Changes in Novice Flyers
Johnson, K. T., Taylor, S., Fedor, S., Jaques, N., Chen, W. '., & Picard, R. W. (2018) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc.2018.8512414 · Cited by 2
“, [2], [5]).”
Psychosocial Stress Reduction (Prong-6)
DePace, N. L., & Colombo, J. (2019) · Springer eBooks · doi:10.1007/978-3-030-17016-5_8 · Cited by 2
Sampling Electrocardiography Confirmation for a Virtual Reality Pain Management Tool
Matsangidou, M., Mauger, A. R., Ang, C. S., & Pattichis, C. S. (2020) · Lecture notes in computer science · doi:10.1007/978-3-030-49698-2_27 · Cited by 2
INVESTIGATION OF HEART RATE VARIABILITY PARAMETERS AND ANXIETY STATUS OF ACTIVE INDIVIDUALS
KAPLAN, E. (2021) · European Journal of Physical Education and Sport Science · doi:10.46827/ejpe.v6i10.3578 · Cited by 2
Mind-Body Practices and the Neuro-psychology of Wellbeing
Gerbarg, P. L., Gootjes, L., & Brown, R. P. (2014) · Cross-cultural advancements in positive psychology · doi:10.1007/978-94-017-8950-9_12 · Cited by 2
Prolonged cardiac activation, stressful events and worry in daily life
Pieper, S. (2000) · Leiden Repository (Leiden University) · Cited by 2
Cardiovascular Benefits of Forgiveness in Women: A Psychophysiological Study
Patel, A. I. (2013) · The Knowledge Bank (The Ohio State University) · Cited by 2
Algorithms and procedures to analyze physiological signals in psychophysiological research
Etzel, J. A. (2006) · doi:10.31274/rtd-180813-10313 · Cited by 2
THE ROLE OF AUTONOMIC BALANCE IN EXPERIENCING EMOTIONS
Pollermann, B. Z., & Archinard, M. (2001) · WORLD SCIENTIFIC eBooks · doi:10.1142/9789812810687_0023 · Cited by 2
Anxiety and Fear-Related Disorders: Generalized Anxiety Disorder
Rosellini, A. J., & Brown, T. A. (2024) · Tasman’s Psychiatry · doi:10.1007/978-3-030-51366-5_74 · Cited by 1
Veerabhadrappa, S. T., Vyas, A. L., Anand, S., & Das, N. (2016) · International Conference on Electrical, Electronics, and Optimization Techniques · doi:10.1109/iceeot.2016.7755196 · Cited by 1
“Low HRV represents a low degree of neurovisceral integration in the organism and a decreased ability to organize resources to meet the demands required in an attentional task [3], [14].”
BackgroundChen, H., Yang, H., Men, C.-E., Shen, C.-H., & Chen, H. (2025) · Journal of Dental Sciences · doi:10.1016/j.jds.2025.02.003 · Cited by 3
“8,13,15,16 Previous studies have shown that the use of a weighted deep pressure blanket during molar extraction can provide benefits similar to deep pressure massage.”
Lee, K. A., Beranbaum, S., Khedari-DePierro, V., Yates, E. H., Yacevich, I., Shankar, A., Enosa, C. E., Son, T. H., Norman, G. J., & D'Andrea, W. M. (2025) · Chronic Stress · doi:10.1177/24705470251324783 · Cited by 1
“42,43,59,66 In the psychological realm, hf-HRV has been highlighted in studies of mental health and other constructs 41,68 – 70 ; however, thresholds using hf-HRV are less clearly established, as most studies are looking at its association with other constructs (eg, stress or emotion regulation)…”
Liu, Y. T., & Lee, S. Y. (2026) · Building and Environment · doi:10.1016/j.buildenv.2026.114791 · Cited by 2
Roach, A. R. (2010) · UKnowledge (University of Kentucky) · Cited by 1
Metadata
- Authors
- Friedman, B. H., & Thayer, J. F.
- Affiliations
- Washington University in St. Louis (US)
- University of Missouri (US)
- Corresponding author
- Friedman, Bruce H.
- Venue
- Journal of Psychosomatic Research
- Publisher
- Elsevier BV
- Published
- 1998-01
- Volume
- 44
- Issue
- 1
- Pages
- 133-151
- ISSN
- 0022-3999 (ISSN-L)
- OpenAlex
- W2167377065
- Cited by
- 616
- References
- 173
- Citations by year
- 2026: 6 · 2025: 14 · 2024: 15 · 2023: 16 · 2022: 18 · 2021: 20 · 2020: 25 · 2019: 27 · 2018: 22 · 2017: 36 · 2016: 43 · 2015: 28 · 2014: 33 · 2013: 25 · 2012: 29
- FWCI
- 2.04
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Psychosomatic Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- heart rate variability, panic disorder, sympathovagal balance, cardiac vagal tone, palpitations, anxiety, emotion regulation, homeostatic model, systems approach, disease classification, pathophysiology
- MeSH terms
- Anxiety Disorders, Arrhythmias, Cardiac, Autonomic Nervous System, Epinephrine, Heart Rate, Homeostasis, Humans, Models, Biological, Sympathetic Nervous System, Vagus Nerve, Comorbidity, Panic Disorder
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