The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
The Neurobiological Approach to Premature Ejaculation
Abstract
PURPOSE: Data showing the neurobiological background of rapid ejaculation was reviewed. In addition, new hypotheses to integrate clinical symptomatology, psychopharmacotherapy and psychotherapy of rapid ejaculation with brain function are provided. MATERIALS AND METHODS: A computerized MEDLINE search, and manual bibliographic review of cross-references and neurobiological animal studies were performed. These reports were analyzed, summarized and compared with the studies performed by the author. RESULTS: The literature on premature ejaculation published between 1887 and 2001 was reviewed. It appeared that the various psychological hypotheses and psychotherapies have not adequately been investigated. In contrast, psychopharmacological treatment studies, animal research data and stopwatch assessments in men with rapid (premature) ejaculation indicate that lifelong rapid ejaculation is a neurobiological phenomenon related to central serotonergic neurotransmission and likely influenced by hereditary factors. CONCLUSIONS: Basic and clinical psychopharmacological studies suggest that premature ejaculation is a not a psychological disturbance but a neurobiological phenomenon.
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Cites
Plasma oxytocin increases in the human sexual response
CARMICHAEL, M. S., HUMBERT, R., DIXEN, J., PALMISANO, G., GREENLEAF, W., & DAVIDSON, J. M. (1987) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-64-1-27 · Cited by 554
Changes in oxytocin and vasopressin secretion during sexual activity in men
MURPHY, M. R., SECKL, J. R., BURTON, S., CHECKLEY, S. A., & LIGHTMAN, S. L. (1987) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-65-4-738 · Cited by 318
Coolen, L. M., Peters, H. J. P. W., & Veening, J. G. (1996) · Brain Research · doi:10.1016/0006-8993(96)00763-9 · Cited by 272
Cited by
Guidelines on male sexual dysfunction: erectile dysfunction and premature ejaculation
Hatzimouratidis, K., Amar, E., Eardley, I., Giuliano, F., Hatzichristou, D., Montorsi, F., Vardi, Y., & Wespes, E. (2010) · European Urology · doi:10.1016/j.eururo.2010.02.020 · Cited by 1,223
Disorders of Orgasm and Ejaculation in Men
Rowland, D., McMahon, C. G., Abdo, C., Chen, J., Jannini, E., Waldinger, M. D., & Ahn, T. Y. (2010) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2010.01782.x · Cited by 508
Self-citationMcMahon, C. G., Althof, S. E., Waldinger, M. D., Porst, H., Dean, J., Sharlip, I. D., Adaikan, P. G., Becher, E., Broderick, G. A., Buvat, J., et al. (2008) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2008.00901.x · Cited by 485
Self-citationA Multinational Population Survey of Intravaginal Ejaculation Latency Time
Waldinger, M. D., Quinn, P., Dilleen, M., Mundayat, R., Schweitzer, D. H., & Boolell, M. (2005) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2005.00070.x · Cited by 469
Self-citationAlthof, S. E., McMahon, C. G., Waldinger, M. D., Serefoglu, E. C., Shindel, A. W., Adaikan, P. G., Becher, E., Dean, J., Giuliano, F., Hellstrom, W. J. G., et al. (2014) · Sexual Medicine · doi:10.1002/sm2.28 · Cited by 444
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Metadata
- Authors
- WALDINGER, M. D.
- Venue
- Journal of Urology
- Published
- 2002-12
- Volume
- 168
- Issue
- 6
- Pages
- 2359-2367
- ISSN
- 0022-5347 (ISSN-L)
- 1527-3792
- OpenAlex
- W2038063468
- Cited by
- 505
- References
- 3
- FWCI
- 12.32
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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