The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
A Prospective European Organization for Research and Treatment of Cancer Genitourinary Group Randomized Trial Comparing Transurethral Resection Followed by a Single Intravesical Instillation of Epirubicin or Water in Single Stage Ta, T1 Papillary Carcinoma of the Bladder
Abstract
A total of 431 eligible patients with solitary, primary or recurrent stages Ta and T1 transitional cell carcinoma of the bladder was included in a randomized multicenter trial to compare a single intravesical instillation of 80 mg. epirubicin with water given immediately after resection, with respect to the disease-free interval and recurrence rate. The interval to initial recurrence was significantly better in favor of the epirubicin group. After a mean followup of 2 years it became evident that the recurrence rate after a single epirubicin instillation was decreased by nearly half with the same trend being found in all subgroups examined. Toxicity was mainly restricted to bladder irritation in plus or minus 10% of the cases. Pathology review brought considerable changes in T category from stages T1 to Ta (53%). Changes in grade were less pronounced but nevertheless important.
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Cites
Zincke, H., Utz, D. C., Taylor, W. F., et al. (1983) · The Journal of Urology · doi:10.1016/s0022-5347(17)52205-3 · Cited by 130
Newling, D. W. W. (1990) · British Journal of Cancer · doi:10.1038/bjc.1990.112 · Cited by 34
Phase II clinical evaluation of 4'-epi-doxorubicin.
Hurteloup, P., Cappelaere, P., Armand, J., & Mathé, G. (1983) · PubMed · Cited by 33
Intravesical Chemoresection with 4'-Epi-Doxorubicin in Patients with Superficial Bladder Tumors
da Silva, F. C., Lj, D., BONO, A., Bollack, C., & Bouffioux, C. (1988) · European Urology · doi:10.1159/000472938 · Cited by 29
Phase I/II study of intravesical epirubicin in patients with carcinoma in situ of the bladder.
Kurth, K. H., Mross, K. B., ten Kate, F. J. W., Weissglas, G., Pj, C., Krueger, C. G., Blom, J., Jm, G., van Caubergh, R. D., & van Aubel, O. G. J. M. (1990) · PubMed · Cited by 5
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Cited by
SYLVESTER, R. J., van der MEIJDEN, A. P. M., & LAMM, D. L. (2002) · Journal of Urology · doi:10.1016/s0022-5347(05)64273-5 · Cited by 1,312
Self-citationEAU Guidelines on Non–Muscle-invasive Urothelial Carcinoma of the Bladder: Update 2013
Babjuk, M., Burger, M., Zigeuner, R., Shariat, S. F., van Rhijn, B. W. G., Compérat, E., Sylvester, R. J., Kaasinen, E., Böhle, A., Palou Redorta, J., et al. (2013) · European Urology · doi:10.1016/j.eururo.2013.06.003 · Cited by 1,174
Self-citationBÖHLE, A., JOCHAM, D., & BOCK, P. R. (2003) · Journal of Urology · doi:10.1016/s0022-5347(05)64043-8 · Cited by 616
Metadata
- Authors
- Oosterlinck, W., Kurth, K. H., Schröder, F., Bultinck, J., Hammond, B., Sylvester, R., & Embers of the European Organization for Research and Treatment of Cancer Genitourinary Group
- Venue
- Journal of Urology
- Published
- 1993-04
- Volume
- 149
- Issue
- 4
- Pages
- 749-752
- ISSN
- 0022-5347 (ISSN-L)
- 1527-3792
- OpenAlex
- W2417407414
- Cited by
- 361
- References
- 5
- FWCI
- 8.57
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: A Prospective European Organization for Research and Treatment of Cancer Genitourinary Group Randomized Trial Comparing Transurethral Resection Followed by a Single Intravesical Instillation of Epirubicin or Water in Single Stage Ta, T1 Papillary Carcinoma of the Bladder. https://app.cochat.ai/papers/10.1016/s0022-5347(17)36198-0
- The paper
- Oosterlinck, W., Kurth, K. H., Schröder, F., Bultinck, J., Hammond, B., Sylvester, R., & Embers of the European Organization for Research and Treatment of Cancer Genitourinary Group. (1993). A Prospective European Organization for Research and Treatment of Cancer Genitourinary Group Randomized Trial Comparing Transurethral Resection Followed by a Single Intravesical Instillation of Epirubicin or Water in Single Stage Ta, T1 Papillary Carcinoma of the Bladder. Journal of Urology. https://doi.org/10.1016/s0022-5347(17)36198-0
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
